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The Germline and Somatic Origins of Prostate Cancer Heterogeneity.

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Title: The Germline and Somatic Origins of Prostate Cancer Heterogeneity.
Authors: Yamaguchi TN; Ontario Institute for Cancer Research, Toronto, Canada.; Department of Human Genetics, University of California, Los Angeles, Los Angeles, California.; Jonsson Comprehensive Cancer Centre, University of California, Los Angeles, Los Angeles, California.; Institute for Precision Health, University of California, Los Angeles, Los Angeles, California., Houlahan KE; Ontario Institute for Cancer Research, Toronto, Canada.; Department of Human Genetics, University of California, Los Angeles, Los Angeles, California.; Jonsson Comprehensive Cancer Centre, University of California, Los Angeles, Los Angeles, California.; Institute for Precision Health, University of California, Los Angeles, Los Angeles, California.; Department of Medical Biophysics, University of Toronto, Toronto, Canada.; Vector Institute, Toronto, Canada.; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, California., Zhu H; Ontario Institute for Cancer Research, Toronto, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, Canada.; Vector Institute, Toronto, Canada.; Princess Margaret Cancer Centre, University Health Network, Toronto, Canada., Kurganovs N; Ontario Institute for Cancer Research, Toronto, Canada.; Princess Margaret Cancer Centre, University Health Network, Toronto, Canada.; Australian Prostate Cancer Research Centre Epworth, Richmond, Australia.; Department of Surgery, The University of Melbourne, Parkville, Australia., Livingstone J; Ontario Institute for Cancer Research, Toronto, Canada.; Department of Human Genetics, University of California, Los Angeles, Los Angeles, California.; Jonsson Comprehensive Cancer Centre, University of California, Los Angeles, Los Angeles, California.; Institute for Precision Health, University of California, Los Angeles, Los Angeles, California., Fox NS; Ontario Institute for Cancer Research, Toronto, Canada.; Department of Human Genetics, University of California, Los Angeles, Los Angeles, California.; Jonsson Comprehensive Cancer Centre, University of California, Los Angeles, Los Angeles, California.; Institute for Precision Health, University of California, Los Angeles, Los Angeles, California.; Department of Medical Biophysics, University of Toronto, Toronto, Canada., Yuan J; Department of Pathology, UT Southwestern Medical Center, Dallas, Texas., Sietsma Penington J; Bioinformatics Division, Walter and Eliza Hall Institute, Parkville, Australia., Jung CH; Melbourne Bioinformatics, The University of Melbourne, Melbourne, Australia., Schwarz T; Bioinformatics Interdepartmental Program, University of California, Los Angeles, Los Angeles, California.; Department of Pathology and Laboratory Medicine, University of California, Los Angeles, Los Angeles, California., Jaratlerdsiri W; Laboratory for Human Comparative and Prostate Cancer Genomics, Genomics and Epigenetics Division, Garvan Institute of Medical Research, Darlinghurst, Australia., van Riet J; Department of Medical Oncology, Erasmus University, Rotterdam, the Netherlands., Georgeson P; Melbourne Bioinformatics, The University of Melbourne, Melbourne, Australia., Mangiola S; Australian Prostate Cancer Research Centre Epworth, Richmond, Australia.; Department of Surgery, The University of Melbourne, Parkville, Australia.; Bioinformatics Division, Walter and Eliza Hall Institute, Parkville, Australia., Taraszka K; Department of Computer Science, University of California, Los Angeles, Los Angeles, California., Lesurf R; Ontario Institute for Cancer Research, Toronto, Canada., Jiang J; Laboratory for Human Comparative and Prostate Cancer Genomics, Genomics and Epigenetics Theme, Garvan Institute of Medical Research, Darlinghurst, Australia., Chow K; Australian Prostate Cancer Research Centre Epworth, Richmond, Australia.; Department of Surgery, The University of Melbourne, Parkville, Australia.; Division of Urology, Royal Melbourne Hospital, Parkville, Australia., Heisler LE; Ontario Institute for Cancer Research, Toronto, Canada., Shiah YJ; Ontario Institute for Cancer Research, Toronto, Canada., Ramanand SG; Department of Pathology, UT Southwestern Medical Center, Dallas, Texas., Clarkson MJ; Australian Prostate Cancer Research Centre Epworth, Richmond, Australia.; Department of Surgery, The University of Melbourne, Parkville, Australia., Nguyen A; Australian Prostate Cancer Research Centre Epworth, Richmond, Australia.; Department of Surgery, The University of Melbourne, Parkville, Australia., Espiritu SMG; Ontario Institute for Cancer Research, Toronto, Canada., Stuchbery R; Australian Prostate Cancer Research Centre Epworth, Richmond, Australia.; Department of Surgery, The University of Melbourne, Parkville, Australia., Jovelin R; Ontario Institute for Cancer Research, Toronto, Canada., Huang V; Ontario Institute for Cancer Research, Toronto, Canada., Bell C; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., O'Connor E; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., McCoy PJ; Australian Prostate Cancer Research Centre Epworth, Richmond, Australia.; Department of Surgery, The University of Melbourne, Parkville, Australia., Lalansingh CM; Ontario Institute for Cancer Research, Toronto, Canada., Cmero M; Australian Prostate Cancer Research Centre Epworth, Richmond, Australia.; Department of Surgery, The University of Melbourne, Parkville, Australia.; Bioinformatics Division, Walter and Eliza Hall Institute, Parkville, Australia., Salcedo A; Ontario Institute for Cancer Research, Toronto, Canada.; Department of Human Genetics, University of California, Los Angeles, Los Angeles, California.; Jonsson Comprehensive Cancer Centre, University of California, Los Angeles, Los Angeles, California.; Institute for Precision Health, University of California, Los Angeles, Los Angeles, California.; Department of Medical Biophysics, University of Toronto, Toronto, Canada., Chan EKF; St Vincent's Clinical School, University of New South Wales, Randwick, Australia.; Department of Urology, St. Vincent's Hospital Sydney, Darlinghurst, Australia., Liu LY; Ontario Institute for Cancer Research, Toronto, Canada.; Department of Human Genetics, University of California, Los Angeles, Los Angeles, California.; Jonsson Comprehensive Cancer Centre, University of California, Los Angeles, Los Angeles, California.; Institute for Precision Health, University of California, Los Angeles, Los Angeles, California.; Department of Medical Biophysics, University of Toronto, Toronto, Canada.; Vector Institute, Toronto, Canada., Stricker PD; Department of Urology, St. Vincent's Hospital Sydney, Darlinghurst, Australia., Bhandari V; Ontario Institute for Cancer Research, Toronto, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, Canada., Bornman RMS; School of Health Systems and Public Health, University of Pretoria, Pretoria, South Africa., Sendorek DHS; Ontario Institute for Cancer Research, Toronto, Canada., Lonie A; Melbourne Bioinformatics, The University of Melbourne, Melbourne, Australia., Prokopec SD; Ontario Institute for Cancer Research, Toronto, Canada., Fraser M; Ontario Institute for Cancer Research, Toronto, Canada.; Princess Margaret Cancer Centre, University Health Network, Toronto, Canada., Peters JS; Australian Prostate Cancer Research Centre Epworth, Richmond, Australia.; Department of Surgery, The University of Melbourne, Parkville, Australia., Foucal A; Ontario Institute for Cancer Research, Toronto, Canada., Mutambirwa SBA; Department of Urology, Sefako Makgatho Health Science University, Medunsa, South Africa., Mcintosh L; Bioinformatics Division, Walter and Eliza Hall Institute, Parkville, Australia., Orain M; Research Centre of CHU de Québec-Université Laval, Québec City, Canada., Wakefield M; Bioinformatics Division, Walter and Eliza Hall Institute, Parkville, Australia., Picard V; Division of Urology and Research Centre of CHU de Québec-Université Laval, Québec City, Canada., Park DJ; Melbourne Bioinformatics, The University of Melbourne, Melbourne, Australia., Hovington H; Division of Urology and Research Centre of CHU de Québec-Université Laval, Québec City, Canada., Kerger M; Australian Prostate Cancer Research Centre Epworth, Richmond, Australia., Bergeron A; Division of Urology and Research Centre of CHU de Québec-Université Laval, Québec City, Canada., Sabelnykova V; Ontario Institute for Cancer Research, Toronto, Canada., Seo JH; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Pomerantz MM; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Zaitlen N; Department of Neurology, University of California, Los Angeles, Los Angeles, California.; Department of Computational Medicine, University of California, Los Angeles, Los Angeles, California., Waszak SM; Centre for Molecular Medicine Norway (NCMM), Nordic EMBL Partnership, University of Oslo and Oslo University Hospital, Oslo, Norway.; Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland., Gusev A; Division of Population Sciences, Dana-Farber Cancer Institute, Boston, Massachusetts.; Division of Genetics, Brigham Women's Hospital and Harvard Medical School, Boston, Massachusetts.; The Eli and Edythe L. Broad Institute, Cambridge, Massachusetts., Lacombe L; Division of Urology and Research Centre of CHU de Québec-Université Laval, Québec City, Canada., Fradet Y; Division of Urology and Research Centre of CHU de Québec-Université Laval, Québec City, Canada., Ryan A; TissuPath Specialist Pathology Services, Mount Waverley, Australia., Kishan AU; Jonsson Comprehensive Cancer Centre, University of California, Los Angeles, Los Angeles, California.; Department of Radiation Oncology, University of California, Los Angeles, Los Angeles, California., Lolkema MP; Department of Computer Science, University of California, Los Angeles, Los Angeles, California.; Center for Personalized Cancer Treatment, Rotterdam, the Netherlands., Weischenfeldt J; Biotech Research & Innovation Centre (BRIC), University of Copenhagen, Copenhagen, Denmark.; Finsen Laboratory, Rigshospitalet, Copenhagen, Denmark.; Department of Urology, Charité-Universitätsmedizin Berlin, Berlin, Germany., Têtu B; Research Centre of CHU de Québec-Université Laval, Québec City, Canada., Costello AJ; Australian Prostate Cancer Research Centre Epworth, Richmond, Australia.; Department of Surgery, The University of Melbourne, Parkville, Australia.; Division of Urology, Royal Melbourne Hospital, Parkville, Australia., Hayes VM; St Vincent's Clinical School, University of New South Wales, Randwick, Australia.; Department of Urology, St. Vincent's Hospital Sydney, Darlinghurst, Australia.; School of Health Systems and Public Health, University of Pretoria, Pretoria, South Africa.; Central Clinical School, University of Sydney, Camperdown, Australia.; Department of Medical Sciences, University of Limpopo, Mankweng, South Africa., Hung RJ; Prosserman Centre for Population Health Research, Lunenfeld-Tanenbaum Research Institute, Toronto, Canada.; Epidemiology Division, Dalla Lana School of Public Health, University of Toronto, Toronto, Canada., He HH; Department of Medical Biophysics, University of Toronto, Toronto, Canada.; Princess Margaret Cancer Centre, University Health Network, Toronto, Canada., McPherson JD; Ontario Institute for Cancer Research, Toronto, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, Canada., Pasaniuc B; Jonsson Comprehensive Cancer Centre, University of California, Los Angeles, Los Angeles, California.; Institute for Precision Health, University of California, Los Angeles, Los Angeles, California.; Department of Pathology and Laboratory Medicine, University of California, Los Angeles, Los Angeles, California.; Department of Computational Medicine, University of California, Los Angeles, Los Angeles, California., van der Kwast T; Princess Margaret Cancer Centre, University Health Network, Toronto, Canada., Papenfuss AT; Melbourne Bioinformatics, The University of Melbourne, Melbourne, Australia.; Department of Medical Biology, University of Melbourne, Parkville, Australia.; Department of Mathematics and Statistics, University of Melbourne, Parkville, Australia.; Peter MacCallum Cancer Centre, Victorian Comprehensive Cancer Centre, Melbourne, Australia.; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Australia., Freedman ML; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Division of Population Sciences, Dana-Farber Cancer Institute, Boston, Massachusetts.; Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, Massachusetts., Pope BJ; Department of Surgery, The University of Melbourne, Parkville, Australia.; Melbourne Bioinformatics, The University of Melbourne, Melbourne, Australia.; Department of Clinical Pathology, The University of Melbourne, Parkville, Australia.; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, Australia.; Department of Medicine, Monash University, Clayton, Australia., Bristow RG; Department of Medical Biophysics, University of Toronto, Toronto, Canada.; Princess Margaret Cancer Centre, University Health Network, Toronto, Canada.; Manchester Cancer Research Centre, Manchester, United Kingdom., Mani RS; Department of Pathology, UT Southwestern Medical Center, Dallas, Texas.; Department of Urology, UT Southwestern Medical Center, Dallas, Texas., Corcoran NM; Australian Prostate Cancer Research Centre Epworth, Richmond, Australia.; Department of Surgery, The University of Melbourne, Parkville, Australia.; Division of Urology, Royal Melbourne Hospital, Parkville, Australia.; Department of Urology, Peninsula Health, Frankston, Australia.; The Victorian Comprehensive Cancer Centre, Parkville, Australia., Reimand J; Ontario Institute for Cancer Research, Toronto, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, Canada., Hovens CM; Australian Prostate Cancer Research Centre Epworth, Richmond, Australia.; Department of Surgery, The University of Melbourne, Parkville, Australia., Boutros PC; Department of Human Genetics, University of California, Los Angeles, Los Angeles, California.; Jonsson Comprehensive Cancer Centre, University of California, Los Angeles, Los Angeles, California.; Institute for Precision Health, University of California, Los Angeles, Los Angeles, California.; Department of Medical Biophysics, University of Toronto, Toronto, Canada.; Vector Institute, Toronto, Canada.; Department of Urology, University of California, Los Angeles, Los Angeles, California.
Source: Cancer discovery [Cancer Discov] 2025 May 02; Vol. 15 (5), pp. 988-1017.
Publication Type: Journal Article
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101561693 Publication Model: Print Cited Medium: Internet ISSN: 2159-8290 (Electronic) Linking ISSN: 21598274 NLM ISO Abbreviation: Cancer Discov Subsets: MEDLINE
Database: MEDLINE Ultimate
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Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 39945744
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
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Items – Name: Title
  Label: Title
  Group: Ti
  Data: The Germline and Somatic Origins of Prostate Cancer Heterogeneity.
– Name: Author
  Label: Authors
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  Data: <searchLink fieldCode="AU" term="%22Yamaguchi+TN%22">Yamaguchi TN</searchLink>; Ontario Institute for Cancer Research, Toronto, Canada.; Department of Human Genetics, University of California, Los Angeles, Los Angeles, California.; Jonsson Comprehensive Cancer Centre, University of California, Los Angeles, Los Angeles, California.; Institute for Precision Health, University of California, Los Angeles, Los Angeles, California.<br /><searchLink fieldCode="AU" term="%22Houlahan+KE%22">Houlahan KE</searchLink>; Ontario Institute for Cancer Research, Toronto, Canada.; Department of Human Genetics, University of California, Los Angeles, Los Angeles, California.; Jonsson Comprehensive Cancer Centre, University of California, Los Angeles, Los Angeles, California.; Institute for Precision Health, University of California, Los Angeles, Los Angeles, California.; Department of Medical Biophysics, University of Toronto, Toronto, Canada.; Vector Institute, Toronto, Canada.; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, California.<br /><searchLink fieldCode="AU" term="%22Zhu+H%22">Zhu H</searchLink>; Ontario Institute for Cancer Research, Toronto, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, Canada.; Vector Institute, Toronto, Canada.; Princess Margaret Cancer Centre, University Health Network, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Kurganovs+N%22">Kurganovs N</searchLink>; Ontario Institute for Cancer Research, Toronto, Canada.; Princess Margaret Cancer Centre, University Health Network, Toronto, Canada.; Australian Prostate Cancer Research Centre Epworth, Richmond, Australia.; Department of Surgery, The University of Melbourne, Parkville, Australia.<br /><searchLink fieldCode="AU" term="%22Livingstone+J%22">Livingstone J</searchLink>; Ontario Institute for Cancer Research, Toronto, Canada.; Department of Human Genetics, University of California, Los Angeles, Los Angeles, California.; Jonsson Comprehensive Cancer Centre, University of California, Los Angeles, Los Angeles, California.; Institute for Precision Health, University of California, Los Angeles, Los Angeles, California.<br /><searchLink fieldCode="AU" term="%22Fox+NS%22">Fox NS</searchLink>; Ontario Institute for Cancer Research, Toronto, Canada.; Department of Human Genetics, University of California, Los Angeles, Los Angeles, California.; Jonsson Comprehensive Cancer Centre, University of California, Los Angeles, Los Angeles, California.; Institute for Precision Health, University of California, Los Angeles, Los Angeles, California.; Department of Medical Biophysics, University of Toronto, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Yuan+J%22">Yuan J</searchLink>; Department of Pathology, UT Southwestern Medical Center, Dallas, Texas.<br /><searchLink fieldCode="AU" term="%22Sietsma+Penington+J%22">Sietsma Penington J</searchLink>; Bioinformatics Division, Walter and Eliza Hall Institute, Parkville, Australia.<br /><searchLink fieldCode="AU" term="%22Jung+CH%22">Jung CH</searchLink>; Melbourne Bioinformatics, The University of Melbourne, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Schwarz+T%22">Schwarz T</searchLink>; Bioinformatics Interdepartmental Program, University of California, Los Angeles, Los Angeles, California.; Department of Pathology and Laboratory Medicine, University of California, Los Angeles, Los Angeles, California.<br /><searchLink fieldCode="AU" term="%22Jaratlerdsiri+W%22">Jaratlerdsiri W</searchLink>; Laboratory for Human Comparative and Prostate Cancer Genomics, Genomics and Epigenetics Division, Garvan Institute of Medical Research, Darlinghurst, Australia.<br /><searchLink fieldCode="AU" term="%22van+Riet+J%22">van Riet J</searchLink>; Department of Medical Oncology, Erasmus University, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Georgeson+P%22">Georgeson P</searchLink>; Melbourne Bioinformatics, The University of Melbourne, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Mangiola+S%22">Mangiola S</searchLink>; Australian Prostate Cancer Research Centre Epworth, Richmond, Australia.; Department of Surgery, The University of Melbourne, Parkville, Australia.; Bioinformatics Division, Walter and Eliza Hall Institute, Parkville, Australia.<br /><searchLink fieldCode="AU" term="%22Taraszka+K%22">Taraszka K</searchLink>; Department of Computer Science, University of California, Los Angeles, Los Angeles, California.<br /><searchLink fieldCode="AU" term="%22Lesurf+R%22">Lesurf R</searchLink>; Ontario Institute for Cancer Research, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Jiang+J%22">Jiang J</searchLink>; Laboratory for Human Comparative and Prostate Cancer Genomics, Genomics and Epigenetics Theme, Garvan Institute of Medical Research, Darlinghurst, Australia.<br /><searchLink fieldCode="AU" term="%22Chow+K%22">Chow K</searchLink>; Australian Prostate Cancer Research Centre Epworth, Richmond, Australia.; Department of Surgery, The University of Melbourne, Parkville, Australia.; Division of Urology, Royal Melbourne Hospital, Parkville, Australia.<br /><searchLink fieldCode="AU" term="%22Heisler+LE%22">Heisler LE</searchLink>; Ontario Institute for Cancer Research, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Shiah+YJ%22">Shiah YJ</searchLink>; Ontario Institute for Cancer Research, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Ramanand+SG%22">Ramanand SG</searchLink>; Department of Pathology, UT Southwestern Medical Center, Dallas, Texas.<br /><searchLink fieldCode="AU" term="%22Clarkson+MJ%22">Clarkson MJ</searchLink>; Australian Prostate Cancer Research Centre Epworth, Richmond, Australia.; Department of Surgery, The University of Melbourne, Parkville, Australia.<br /><searchLink fieldCode="AU" term="%22Nguyen+A%22">Nguyen A</searchLink>; Australian Prostate Cancer Research Centre Epworth, Richmond, Australia.; Department of Surgery, The University of Melbourne, Parkville, Australia.<br /><searchLink fieldCode="AU" term="%22Espiritu+SMG%22">Espiritu SMG</searchLink>; Ontario Institute for Cancer Research, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Stuchbery+R%22">Stuchbery R</searchLink>; Australian Prostate Cancer Research Centre Epworth, Richmond, Australia.; Department of Surgery, The University of Melbourne, Parkville, Australia.<br /><searchLink fieldCode="AU" term="%22Jovelin+R%22">Jovelin R</searchLink>; Ontario Institute for Cancer Research, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Huang+V%22">Huang V</searchLink>; Ontario Institute for Cancer Research, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Bell+C%22">Bell C</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22O'Connor+E%22">O'Connor E</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22McCoy+PJ%22">McCoy PJ</searchLink>; Australian Prostate Cancer Research Centre Epworth, Richmond, Australia.; Department of Surgery, The University of Melbourne, Parkville, Australia.<br /><searchLink fieldCode="AU" term="%22Lalansingh+CM%22">Lalansingh CM</searchLink>; Ontario Institute for Cancer Research, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Cmero+M%22">Cmero M</searchLink>; Australian Prostate Cancer Research Centre Epworth, Richmond, Australia.; Department of Surgery, The University of Melbourne, Parkville, Australia.; Bioinformatics Division, Walter and Eliza Hall Institute, Parkville, Australia.<br /><searchLink fieldCode="AU" term="%22Salcedo+A%22">Salcedo A</searchLink>; Ontario Institute for Cancer Research, Toronto, Canada.; Department of Human Genetics, University of California, Los Angeles, Los Angeles, California.; Jonsson Comprehensive Cancer Centre, University of California, Los Angeles, Los Angeles, California.; Institute for Precision Health, University of California, Los Angeles, Los Angeles, California.; Department of Medical Biophysics, University of Toronto, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Chan+EKF%22">Chan EKF</searchLink>; St Vincent's Clinical School, University of New South Wales, Randwick, Australia.; Department of Urology, St. Vincent's Hospital Sydney, Darlinghurst, Australia.<br /><searchLink fieldCode="AU" term="%22Liu+LY%22">Liu LY</searchLink>; Ontario Institute for Cancer Research, Toronto, Canada.; Department of Human Genetics, University of California, Los Angeles, Los Angeles, California.; Jonsson Comprehensive Cancer Centre, University of California, Los Angeles, Los Angeles, California.; Institute for Precision Health, University of California, Los Angeles, Los Angeles, California.; Department of Medical Biophysics, University of Toronto, Toronto, Canada.; Vector Institute, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Stricker+PD%22">Stricker PD</searchLink>; Department of Urology, St. Vincent's Hospital Sydney, Darlinghurst, Australia.<br /><searchLink fieldCode="AU" term="%22Bhandari+V%22">Bhandari V</searchLink>; Ontario Institute for Cancer Research, Toronto, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Bornman+RMS%22">Bornman RMS</searchLink>; School of Health Systems and Public Health, University of Pretoria, Pretoria, South Africa.<br /><searchLink fieldCode="AU" term="%22Sendorek+DHS%22">Sendorek DHS</searchLink>; Ontario Institute for Cancer Research, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Lonie+A%22">Lonie A</searchLink>; Melbourne Bioinformatics, The University of Melbourne, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Prokopec+SD%22">Prokopec SD</searchLink>; Ontario Institute for Cancer Research, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Fraser+M%22">Fraser M</searchLink>; Ontario Institute for Cancer Research, Toronto, Canada.; Princess Margaret Cancer Centre, University Health Network, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Peters+JS%22">Peters JS</searchLink>; Australian Prostate Cancer Research Centre Epworth, Richmond, Australia.; Department of Surgery, The University of Melbourne, Parkville, Australia.<br /><searchLink fieldCode="AU" term="%22Foucal+A%22">Foucal A</searchLink>; Ontario Institute for Cancer Research, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Mutambirwa+SBA%22">Mutambirwa SBA</searchLink>; Department of Urology, Sefako Makgatho Health Science University, Medunsa, South Africa.<br /><searchLink fieldCode="AU" term="%22Mcintosh+L%22">Mcintosh L</searchLink>; Bioinformatics Division, Walter and Eliza Hall Institute, Parkville, Australia.<br /><searchLink fieldCode="AU" term="%22Orain+M%22">Orain M</searchLink>; Research Centre of CHU de Québec-Université Laval, Québec City, Canada.<br /><searchLink fieldCode="AU" term="%22Wakefield+M%22">Wakefield M</searchLink>; Bioinformatics Division, Walter and Eliza Hall Institute, Parkville, Australia.<br /><searchLink fieldCode="AU" term="%22Picard+V%22">Picard V</searchLink>; Division of Urology and Research Centre of CHU de Québec-Université Laval, Québec City, Canada.<br /><searchLink fieldCode="AU" term="%22Park+DJ%22">Park DJ</searchLink>; Melbourne Bioinformatics, The University of Melbourne, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Hovington+H%22">Hovington H</searchLink>; Division of Urology and Research Centre of CHU de Québec-Université Laval, Québec City, Canada.<br /><searchLink fieldCode="AU" term="%22Kerger+M%22">Kerger M</searchLink>; Australian Prostate Cancer Research Centre Epworth, Richmond, Australia.<br /><searchLink fieldCode="AU" term="%22Bergeron+A%22">Bergeron A</searchLink>; Division of Urology and Research Centre of CHU de Québec-Université Laval, Québec City, Canada.<br /><searchLink fieldCode="AU" term="%22Sabelnykova+V%22">Sabelnykova V</searchLink>; Ontario Institute for Cancer Research, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Seo+JH%22">Seo JH</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Pomerantz+MM%22">Pomerantz MM</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Zaitlen+N%22">Zaitlen N</searchLink>; Department of Neurology, University of California, Los Angeles, Los Angeles, California.; Department of Computational Medicine, University of California, Los Angeles, Los Angeles, California.<br /><searchLink fieldCode="AU" term="%22Waszak+SM%22">Waszak SM</searchLink>; Centre for Molecular Medicine Norway (NCMM), Nordic EMBL Partnership, University of Oslo and Oslo University Hospital, Oslo, Norway.; Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Gusev+A%22">Gusev A</searchLink>; Division of Population Sciences, Dana-Farber Cancer Institute, Boston, Massachusetts.; Division of Genetics, Brigham Women's Hospital and Harvard Medical School, Boston, Massachusetts.; The Eli and Edythe L. Broad Institute, Cambridge, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Lacombe+L%22">Lacombe L</searchLink>; Division of Urology and Research Centre of CHU de Québec-Université Laval, Québec City, Canada.<br /><searchLink fieldCode="AU" term="%22Fradet+Y%22">Fradet Y</searchLink>; Division of Urology and Research Centre of CHU de Québec-Université Laval, Québec City, Canada.<br /><searchLink fieldCode="AU" term="%22Ryan+A%22">Ryan A</searchLink>; TissuPath Specialist Pathology Services, Mount Waverley, Australia.<br /><searchLink fieldCode="AU" term="%22Kishan+AU%22">Kishan AU</searchLink>; Jonsson Comprehensive Cancer Centre, University of California, Los Angeles, Los Angeles, California.; Department of Radiation Oncology, University of California, Los Angeles, Los Angeles, California.<br /><searchLink fieldCode="AU" term="%22Lolkema+MP%22">Lolkema MP</searchLink>; Department of Computer Science, University of California, Los Angeles, Los Angeles, California.; Center for Personalized Cancer Treatment, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Weischenfeldt+J%22">Weischenfeldt J</searchLink>; Biotech Research & Innovation Centre (BRIC), University of Copenhagen, Copenhagen, Denmark.; Finsen Laboratory, Rigshospitalet, Copenhagen, Denmark.; Department of Urology, Charité-Universitätsmedizin Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Têtu+B%22">Têtu B</searchLink>; Research Centre of CHU de Québec-Université Laval, Québec City, Canada.<br /><searchLink fieldCode="AU" term="%22Costello+AJ%22">Costello AJ</searchLink>; Australian Prostate Cancer Research Centre Epworth, Richmond, Australia.; Department of Surgery, The University of Melbourne, Parkville, Australia.; Division of Urology, Royal Melbourne Hospital, Parkville, Australia.<br /><searchLink fieldCode="AU" term="%22Hayes+VM%22">Hayes VM</searchLink>; St Vincent's Clinical School, University of New South Wales, Randwick, Australia.; Department of Urology, St. Vincent's Hospital Sydney, Darlinghurst, Australia.; School of Health Systems and Public Health, University of Pretoria, Pretoria, South Africa.; Central Clinical School, University of Sydney, Camperdown, Australia.; Department of Medical Sciences, University of Limpopo, Mankweng, South Africa.<br /><searchLink fieldCode="AU" term="%22Hung+RJ%22">Hung RJ</searchLink>; Prosserman Centre for Population Health Research, Lunenfeld-Tanenbaum Research Institute, Toronto, Canada.; Epidemiology Division, Dalla Lana School of Public Health, University of Toronto, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22He+HH%22">He HH</searchLink>; Department of Medical Biophysics, University of Toronto, Toronto, Canada.; Princess Margaret Cancer Centre, University Health Network, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22McPherson+JD%22">McPherson JD</searchLink>; Ontario Institute for Cancer Research, Toronto, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Pasaniuc+B%22">Pasaniuc B</searchLink>; Jonsson Comprehensive Cancer Centre, University of California, Los Angeles, Los Angeles, California.; Institute for Precision Health, University of California, Los Angeles, Los Angeles, California.; Department of Pathology and Laboratory Medicine, University of California, Los Angeles, Los Angeles, California.; Department of Computational Medicine, University of California, Los Angeles, Los Angeles, California.<br /><searchLink fieldCode="AU" term="%22van+der+Kwast+T%22">van der Kwast T</searchLink>; Princess Margaret Cancer Centre, University Health Network, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Papenfuss+AT%22">Papenfuss AT</searchLink>; Melbourne Bioinformatics, The University of Melbourne, Melbourne, Australia.; Department of Medical Biology, University of Melbourne, Parkville, Australia.; Department of Mathematics and Statistics, University of Melbourne, Parkville, Australia.; Peter MacCallum Cancer Centre, Victorian Comprehensive Cancer Centre, Melbourne, Australia.; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Australia.<br /><searchLink fieldCode="AU" term="%22Freedman+ML%22">Freedman ML</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Division of Population Sciences, Dana-Farber Cancer Institute, Boston, Massachusetts.; Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Pope+BJ%22">Pope BJ</searchLink>; Department of Surgery, The University of Melbourne, Parkville, Australia.; Melbourne Bioinformatics, The University of Melbourne, Melbourne, Australia.; Department of Clinical Pathology, The University of Melbourne, Parkville, Australia.; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, Australia.; Department of Medicine, Monash University, Clayton, Australia.<br /><searchLink fieldCode="AU" term="%22Bristow+RG%22">Bristow RG</searchLink>; Department of Medical Biophysics, University of Toronto, Toronto, Canada.; Princess Margaret Cancer Centre, University Health Network, Toronto, Canada.; Manchester Cancer Research Centre, Manchester, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Mani+RS%22">Mani RS</searchLink>; Department of Pathology, UT Southwestern Medical Center, Dallas, Texas.; Department of Urology, UT Southwestern Medical Center, Dallas, Texas.<br /><searchLink fieldCode="AU" term="%22Corcoran+NM%22">Corcoran NM</searchLink>; Australian Prostate Cancer Research Centre Epworth, Richmond, Australia.; Department of Surgery, The University of Melbourne, Parkville, Australia.; Division of Urology, Royal Melbourne Hospital, Parkville, Australia.; Department of Urology, Peninsula Health, Frankston, Australia.; The Victorian Comprehensive Cancer Centre, Parkville, Australia.<br /><searchLink fieldCode="AU" term="%22Reimand+J%22">Reimand J</searchLink>; Ontario Institute for Cancer Research, Toronto, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Hovens+CM%22">Hovens CM</searchLink>; Australian Prostate Cancer Research Centre Epworth, Richmond, Australia.; Department of Surgery, The University of Melbourne, Parkville, Australia.<br /><searchLink fieldCode="AU" term="%22Boutros+PC%22">Boutros PC</searchLink>; Department of Human Genetics, University of California, Los Angeles, Los Angeles, California.; Jonsson Comprehensive Cancer Centre, University of California, Los Angeles, Los Angeles, California.; Institute for Precision Health, University of California, Los Angeles, Los Angeles, California.; Department of Medical Biophysics, University of Toronto, Toronto, Canada.; Vector Institute, Toronto, Canada.; Department of Urology, University of California, Los Angeles, Los Angeles, California.
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  Data: <searchLink fieldCode="JN" term="%22101561693%22">Cancer discovery</searchLink> [Cancer Discov] 2025 May 02; Vol. 15 (5), pp. 988-1017.
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              Text: 2025 May 02
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