Differential associations of somatic and cognitive-affective symptoms of depression with inflammation and insulin resistance: cross-sectional and longitudinal results from the Emotional Distress Sub-Study of the GRADE study.

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Title: Differential associations of somatic and cognitive-affective symptoms of depression with inflammation and insulin resistance: cross-sectional and longitudinal results from the Emotional Distress Sub-Study of the GRADE study.
Authors: Ehrmann D; Research Institute Diabetes Academy Mergentheim (FIDAM), Bad Mergentheim, Germany. ehrmann@fidam.de.; Department of Clinical Psychology and Psychotherapy, University of Bamberg, Bamberg, Germany. ehrmann@fidam.de., Krause-Steinrauf H; The Biostatistics Center, Department of Biostatistics and Bioinformatics, Milken Institute School of Public Health, The George Washington University, Rockville, MD, USA., Uschner D; The Biostatistics Center, Department of Biostatistics and Bioinformatics, Milken Institute School of Public Health, The George Washington University, Rockville, MD, USA., Wen H; The Biostatistics Center, Department of Biostatistics and Bioinformatics, Milken Institute School of Public Health, The George Washington University, Rockville, MD, USA., Hoogendoorn CJ; Ferkauf Graduate School of Psychology, Yeshiva University, Bronx, NY, USA.; Department of Medicine (Endocrinology), Albert Einstein College of Medicine, Bronx, NY, USA., Crespo-Ramos G; Department of Medicine (Endocrinology), Albert Einstein College of Medicine, Bronx, NY, USA., Presley C; Department of Medicine (General Internal and Preventive Medicine), University of Alabama at Birmingham, Birmingham, AL, USA., Arends VL; Advanced Research and Diagnostic Laboratory, Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, USA., Cohen RM; Division of Endocrinology, Diabetes & Metabolism, Department of Medicine, University of Cincinnati College of Medicine & Endocrine Section, Cincinnati VA Medical Center, Cincinnati, OH, USA., Garvey WT; University of Alabama at Birmingham, Birmingham, AL, USA., Martens T; International Diabetes Center, HealthPartners Institute, Minneapolis, MN, USA., Willis HJ; International Diabetes Center, HealthPartners Institute, Minneapolis, MN, USA., Cherrington A; Department of Medicine (General Internal and Preventive Medicine), University of Alabama at Birmingham, Birmingham, AL, USA., Gonzalez JS; Ferkauf Graduate School of Psychology, Yeshiva University, Bronx, NY, USA.; Department of Medicine (Endocrinology), Albert Einstein College of Medicine, Bronx, NY, USA.; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA.; New York-Regional Center for Diabetes Translation Research, Albert Einstein College of Medicine, Bronx, NY, USA.
Corporate Authors: GRADE Research Group
Source: Diabetologia [Diabetologia] 2025 Jul; Vol. 68 (7), pp. 1403-1415. Date of Electronic Publication: 2025 Feb 14.
Publication Type: Clinical Trial, Phase III; Journal Article; Multicenter Study; Randomized Controlled Trial
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0006777 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0428 (Electronic) Linking ISSN: 0012186X NLM ISO Abbreviation: Diabetologia Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1432-0428
DOI:10.1007/s00125-025-06369-8