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LmCen-/- based vaccine is protective against canine visceral leishmaniasis following three natural exposures in Tunisia.

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Title: LmCen-/- based vaccine is protective against canine visceral leishmaniasis following three natural exposures in Tunisia.
Authors: Boussoffara T; Laboratory of Transmission, Control, and Immunobiology of Infections. Pasteur Institute of Tunis. University of Tunis El Manar, Tunis, Tunisia., Labidi I; Unit of Vector Ecology, Pasteur Institute of Tunis, Tunis, Tunisia., Trimèche M; Laboratory of Transmission, Control, and Immunobiology of Infections. Pasteur Institute of Tunis. University of Tunis El Manar, Tunis, Tunisia., Chelbi I; Laboratory of Transmission, Control, and Immunobiology of Infections. Pasteur Institute of Tunis. University of Tunis El Manar, Tunis, Tunisia.; Unit of Vector Ecology, Pasteur Institute of Tunis, Tunis, Tunisia., Dachraoui K; Laboratory of Transmission, Control, and Immunobiology of Infections. Pasteur Institute of Tunis. University of Tunis El Manar, Tunis, Tunisia.; Unit of Vector Ecology, Pasteur Institute of Tunis, Tunis, Tunisia., Msallem N; Unit of Vector Ecology, Pasteur Institute of Tunis, Tunis, Tunisia., Abdo Saghir Abbas M; Laboratory of Transmission, Control, and Immunobiology of Infections. Pasteur Institute of Tunis. University of Tunis El Manar, Tunis, Tunisia.; Unit of Vector Ecology, Pasteur Institute of Tunis, Tunis, Tunisia., Cherni S; Laboratory of Transmission, Control, and Immunobiology of Infections. Pasteur Institute of Tunis. University of Tunis El Manar, Tunis, Tunisia.; Unit of Vector Ecology, Pasteur Institute of Tunis, Tunis, Tunisia., Singh KP; Gennova Biopharmaceuticals Limited, Hinjewadi Phase II, Pune, Maharashtra, India., Kaviraj S; Gennova Biopharmaceuticals Limited, Hinjewadi Phase II, Pune, Maharashtra, India., Dey R; Division of Emerging and Transfusion Transmitted Diseases, Office of Blood Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, USA., Varikuti S; The Ohio State University, Columbus, Ohio, USA., Gannavaram S; Division of Emerging and Transfusion Transmitted Diseases, Office of Blood Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, USA., da S Pereira L; Division of Emerging and Transfusion Transmitted Diseases, Office of Blood Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, USA., Zhang WW; Department of Microbiology and Immunology, McGill University, Montreal, QC, Canada., Lypaczewski P; Department of Microbiology and Immunology, McGill University, Montreal, QC, Canada., Hamano S; Department of Parasitology, Institute of Tropical Medicine (NEKKEN), The Joint Usage/Research Center on Tropical Disease, Nagasaki University, Nagasaki, Japan., Kato H; Division of Medical Zoology, Department of Infection and Immunity, Jichi Medical University, Tochigi, Japan., Singh S; Gennova Biopharmaceuticals Limited, Hinjewadi Phase II, Pune, Maharashtra, India., Louzir H; Laboratory of Transmission, Control, and Immunobiology of Infections. Pasteur Institute of Tunis. University of Tunis El Manar, Tunis, Tunisia., Nakhasi HL; Division of Emerging and Transfusion Transmitted Diseases, Office of Blood Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, USA., Satoskar AR; The Ohio State University, Columbus, Ohio, USA., Matlashewski G; Department of Microbiology and Immunology, McGill University, Montreal, QC, Canada., Zhioua E; Laboratory of Transmission, Control, and Immunobiology of Infections. Pasteur Institute of Tunis. University of Tunis El Manar, Tunis, Tunisia. elyes.zhioua@gmail.com.; Unit of Vector Ecology, Pasteur Institute of Tunis, Tunis, Tunisia. elyes.zhioua@gmail.com.
Source: NPJ vaccines [NPJ Vaccines] 2025 Feb 14; Vol. 10 (1), pp. 31. Date of Electronic Publication: 2025 Feb 14.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature in partnership with the Sealy Center for Vaccine Development Country of Publication: England NLM ID: 101699863 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-0105 (Electronic) Linking ISSN: 20590105 NLM ISO Abbreviation: NPJ Vaccines Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: LmCen<superscript>-/-</superscript> based vaccine is protective against canine visceral leishmaniasis following three natural exposures in Tunisia.
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  Data: <searchLink fieldCode="AU" term="%22Boussoffara+T%22">Boussoffara T</searchLink>; Laboratory of Transmission, Control, and Immunobiology of Infections. Pasteur Institute of Tunis. University of Tunis El Manar, Tunis, Tunisia.<br /><searchLink fieldCode="AU" term="%22Labidi+I%22">Labidi I</searchLink>; Unit of Vector Ecology, Pasteur Institute of Tunis, Tunis, Tunisia.<br /><searchLink fieldCode="AU" term="%22Trimèche+M%22">Trimèche M</searchLink>; Laboratory of Transmission, Control, and Immunobiology of Infections. Pasteur Institute of Tunis. University of Tunis El Manar, Tunis, Tunisia.<br /><searchLink fieldCode="AU" term="%22Chelbi+I%22">Chelbi I</searchLink>; Laboratory of Transmission, Control, and Immunobiology of Infections. Pasteur Institute of Tunis. University of Tunis El Manar, Tunis, Tunisia.; Unit of Vector Ecology, Pasteur Institute of Tunis, Tunis, Tunisia.<br /><searchLink fieldCode="AU" term="%22Dachraoui+K%22">Dachraoui K</searchLink>; Laboratory of Transmission, Control, and Immunobiology of Infections. Pasteur Institute of Tunis. University of Tunis El Manar, Tunis, Tunisia.; Unit of Vector Ecology, Pasteur Institute of Tunis, Tunis, Tunisia.<br /><searchLink fieldCode="AU" term="%22Msallem+N%22">Msallem N</searchLink>; Unit of Vector Ecology, Pasteur Institute of Tunis, Tunis, Tunisia.<br /><searchLink fieldCode="AU" term="%22Abdo+Saghir+Abbas+M%22">Abdo Saghir Abbas M</searchLink>; Laboratory of Transmission, Control, and Immunobiology of Infections. Pasteur Institute of Tunis. University of Tunis El Manar, Tunis, Tunisia.; Unit of Vector Ecology, Pasteur Institute of Tunis, Tunis, Tunisia.<br /><searchLink fieldCode="AU" term="%22Cherni+S%22">Cherni S</searchLink>; Laboratory of Transmission, Control, and Immunobiology of Infections. Pasteur Institute of Tunis. University of Tunis El Manar, Tunis, Tunisia.; Unit of Vector Ecology, Pasteur Institute of Tunis, Tunis, Tunisia.<br /><searchLink fieldCode="AU" term="%22Singh+KP%22">Singh KP</searchLink>; Gennova Biopharmaceuticals Limited, Hinjewadi Phase II, Pune, Maharashtra, India.<br /><searchLink fieldCode="AU" term="%22Kaviraj+S%22">Kaviraj S</searchLink>; Gennova Biopharmaceuticals Limited, Hinjewadi Phase II, Pune, Maharashtra, India.<br /><searchLink fieldCode="AU" term="%22Dey+R%22">Dey R</searchLink>; Division of Emerging and Transfusion Transmitted Diseases, Office of Blood Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, USA.<br /><searchLink fieldCode="AU" term="%22Varikuti+S%22">Varikuti S</searchLink>; The Ohio State University, Columbus, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Gannavaram+S%22">Gannavaram S</searchLink>; Division of Emerging and Transfusion Transmitted Diseases, Office of Blood Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, USA.<br /><searchLink fieldCode="AU" term="%22da+S+Pereira+L%22">da S Pereira L</searchLink>; Division of Emerging and Transfusion Transmitted Diseases, Office of Blood Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+WW%22">Zhang WW</searchLink>; Department of Microbiology and Immunology, McGill University, Montreal, QC, Canada.<br /><searchLink fieldCode="AU" term="%22Lypaczewski+P%22">Lypaczewski P</searchLink>; Department of Microbiology and Immunology, McGill University, Montreal, QC, Canada.<br /><searchLink fieldCode="AU" term="%22Hamano+S%22">Hamano S</searchLink>; Department of Parasitology, Institute of Tropical Medicine (NEKKEN), The Joint Usage/Research Center on Tropical Disease, Nagasaki University, Nagasaki, Japan.<br /><searchLink fieldCode="AU" term="%22Kato+H%22">Kato H</searchLink>; Division of Medical Zoology, Department of Infection and Immunity, Jichi Medical University, Tochigi, Japan.<br /><searchLink fieldCode="AU" term="%22Singh+S%22">Singh S</searchLink>; Gennova Biopharmaceuticals Limited, Hinjewadi Phase II, Pune, Maharashtra, India.<br /><searchLink fieldCode="AU" term="%22Louzir+H%22">Louzir H</searchLink>; Laboratory of Transmission, Control, and Immunobiology of Infections. Pasteur Institute of Tunis. University of Tunis El Manar, Tunis, Tunisia.<br /><searchLink fieldCode="AU" term="%22Nakhasi+HL%22">Nakhasi HL</searchLink>; Division of Emerging and Transfusion Transmitted Diseases, Office of Blood Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, USA.<br /><searchLink fieldCode="AU" term="%22Satoskar+AR%22">Satoskar AR</searchLink>; The Ohio State University, Columbus, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Matlashewski+G%22">Matlashewski G</searchLink>; Department of Microbiology and Immunology, McGill University, Montreal, QC, Canada.<br /><searchLink fieldCode="AU" term="%22Zhioua+E%22">Zhioua E</searchLink>; Laboratory of Transmission, Control, and Immunobiology of Infections. Pasteur Institute of Tunis. University of Tunis El Manar, Tunis, Tunisia. elyes.zhioua@gmail.com.; Unit of Vector Ecology, Pasteur Institute of Tunis, Tunis, Tunisia. elyes.zhioua@gmail.com.
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  Data: <searchLink fieldCode="JN" term="%22101699863%22">NPJ vaccines</searchLink> [NPJ Vaccines] 2025 Feb 14; Vol. 10 (1), pp. 31. <i>Date of Electronic Publication: </i>2025 Feb 14.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Nature+in+partnership+with+the+Sealy+Center+for+Vaccine+Development%22">Springer Nature in partnership with the Sealy Center for Vaccine Development </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101699863 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2059-0105 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220590105%22">20590105 </searchLink><i>NLM ISO Abbreviation: </i>NPJ Vaccines <i>Subsets: </i>PubMed not MEDLINE
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