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Treatment De-escalation in Relapsing-Remitting Multiple Sclerosis: An Observational Study.

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Title: Treatment De-escalation in Relapsing-Remitting Multiple Sclerosis: An Observational Study.
Authors: Müller J; CORe, Department of Medicine, University of Melbourne, Melbourne, VIC, 3000, Australia.; Neuroimmunology Centre, Department of Neurology, Royal Melbourne Hospital, Melbourne, Australia.; Neurologic Clinic and Policlinic, MS Center and Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel and University of Basel, Basel, Switzerland., Sharmin S; CORe, Department of Medicine, University of Melbourne, Melbourne, VIC, 3000, Australia.; Neuroimmunology Centre, Department of Neurology, Royal Melbourne Hospital, Melbourne, Australia., Lorscheider J; Neurologic Clinic and Policlinic, MS Center and Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel and University of Basel, Basel, Switzerland., Horakova D; Department of Neurology and Center of Clinical Neuroscience, First Faculty of Medicine, Charles University in Prague and General University Hospital, Prague, Czech Republic., Kubala Havrdova E; Department of Neurology and Center of Clinical Neuroscience, First Faculty of Medicine, Charles University in Prague and General University Hospital, Prague, Czech Republic., Eichau S; Department of Neurology, Hospital Universitario Virgen Macarena, Sevilla, Spain., Patti F; Department of Medical and Surgical Sciences and Advanced Technologies, GF Ingrassia, Catania, Italy., Grammond P; CISSS Chaudière-Appalache, Levis, Canada., Buzzard K; Department of Neurosciences, Box Hill Hospital, Melbourne, Australia., Skibina O; Department of Neurology, Box Hill Hospital, Melbourne, Australia., Prat A; CHUM MS Center, Universite de Montreal, Montreal, Canada., Girard M; CHUM MS Center, Universite de Montreal, Montreal, Canada., Grand'Maison F; Neuro Rive-Sud, Longueuil, QC, Canada., Alroughani R; Division of Neurology, Department of Medicine, Amiri Hospital, Sharq, Kuwait., Lechner-Scott J; Hunter Medical Research Institute, University Newcastle, Newcastle, Australia., Spitaleri D; Azienda Ospedaliera di Rilievo Nazionale San Giuseppe Moscati Avellino, Avellino, Italy., Barnett M; Brain and Mind Centre, Sydney, Australia., Cartechini E; Neurology Unit, P O Unico Macerata, ast Macerata, Macerata, Italy., Sa MJ; Department of Neurology, Centro Hospitalar Universitario de Sao Joao, and Faculty of Health Sciences, University Fernando Pessoa, Porto, Portugal., Gerlach O; Academic MS Center Zuyd, Department of Neurology, Zuyderland Medical Center, Sittard-Geleen, The Netherlands.; School for Mental Health and Neuroscience, Department of Neurology, Maastricht University Medical Center, Maastricht, The Netherlands., van der Walt A; Department of Neurology, The Alfred Hospital, Melbourne, Australia., Butzkueven H; Department of Neurology, The Alfred Hospital, Melbourne, Australia., Prevost J; CSSS Saint-Jérôme, Saint-Jerome, QC, Canada., Castillo-Triviño T; Hospital Universitario Donostia, San Sebastián, Spain., Yamout B; Neurology Institute, Harley Street Medical Center, Abu Dhabi, UAE., Khoury SJ; Nehme and Therese Tohme Multiple Sclerosis Center, American University of Beirut Medical Center, Beirut, Lebanon., Yaldizli Ö; Neurologic Clinic and Policlinic, MS Center and Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel and University of Basel, Basel, Switzerland., Derfuss T; Neurologic Clinic and Policlinic, MS Center and Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel and University of Basel, Basel, Switzerland., Granziera C; Neurologic Clinic and Policlinic, MS Center and Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel and University of Basel, Basel, Switzerland., Kuhle J; Neurologic Clinic and Policlinic, MS Center and Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel and University of Basel, Basel, Switzerland., Kappos L; Neurologic Clinic and Policlinic, MS Center and Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel and University of Basel, Basel, Switzerland., Roos I; CORe, Department of Medicine, University of Melbourne, Melbourne, VIC, 3000, Australia.; Neuroimmunology Centre, Department of Neurology, Royal Melbourne Hospital, Melbourne, Australia., Kalincik T; CORe, Department of Medicine, University of Melbourne, Melbourne, VIC, 3000, Australia. tomas.kalincik@unimelb.edu.au.; Neuroimmunology Centre, Department of Neurology, Royal Melbourne Hospital, Melbourne, Australia. tomas.kalincik@unimelb.edu.au.
Corporate Authors: MSBase Study Group
Source: CNS drugs [CNS Drugs] 2025 Apr; Vol. 39 (4), pp. 403-416. Date of Electronic Publication: 2025 Feb 14.
Publication Type: Journal Article; Observational Study; Multicenter Study
Journal Info: Publisher: Adis, Springer International Country of Publication: New Zealand NLM ID: 9431220 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-1934 (Electronic) Linking ISSN: 11727047 NLM ISO Abbreviation: CNS Drugs Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Treatment De-escalation in Relapsing-Remitting Multiple Sclerosis: An Observational Study.
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  Data: <searchLink fieldCode="AU" term="%22Müller+J%22">Müller J</searchLink>; CORe, Department of Medicine, University of Melbourne, Melbourne, VIC, 3000, Australia.; Neuroimmunology Centre, Department of Neurology, Royal Melbourne Hospital, Melbourne, Australia.; Neurologic Clinic and Policlinic, MS Center and Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel and University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Sharmin+S%22">Sharmin S</searchLink>; CORe, Department of Medicine, University of Melbourne, Melbourne, VIC, 3000, Australia.; Neuroimmunology Centre, Department of Neurology, Royal Melbourne Hospital, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Lorscheider+J%22">Lorscheider J</searchLink>; Neurologic Clinic and Policlinic, MS Center and Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel and University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Horakova+D%22">Horakova D</searchLink>; Department of Neurology and Center of Clinical Neuroscience, First Faculty of Medicine, Charles University in Prague and General University Hospital, Prague, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Kubala+Havrdova+E%22">Kubala Havrdova E</searchLink>; Department of Neurology and Center of Clinical Neuroscience, First Faculty of Medicine, Charles University in Prague and General University Hospital, Prague, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Eichau+S%22">Eichau S</searchLink>; Department of Neurology, Hospital Universitario Virgen Macarena, Sevilla, Spain.<br /><searchLink fieldCode="AU" term="%22Patti+F%22">Patti F</searchLink>; Department of Medical and Surgical Sciences and Advanced Technologies, GF Ingrassia, Catania, Italy.<br /><searchLink fieldCode="AU" term="%22Grammond+P%22">Grammond P</searchLink>; CISSS Chaudière-Appalache, Levis, Canada.<br /><searchLink fieldCode="AU" term="%22Buzzard+K%22">Buzzard K</searchLink>; Department of Neurosciences, Box Hill Hospital, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Skibina+O%22">Skibina O</searchLink>; 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Neurologic Clinic and Policlinic, MS Center and Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel and University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Kuhle+J%22">Kuhle J</searchLink>; Neurologic Clinic and Policlinic, MS Center and Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel and University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Kappos+L%22">Kappos L</searchLink>; Neurologic Clinic and Policlinic, MS Center and Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel and University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Roos+I%22">Roos I</searchLink>; CORe, Department of Medicine, University of Melbourne, Melbourne, VIC, 3000, Australia.; Neuroimmunology Centre, Department of Neurology, Royal Melbourne Hospital, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Kalincik+T%22">Kalincik T</searchLink>; CORe, Department of Medicine, University of Melbourne, Melbourne, VIC, 3000, Australia. tomas.kalincik@unimelb.edu.au.; Neuroimmunology Centre, Department of Neurology, Royal Melbourne Hospital, Melbourne, Australia. tomas.kalincik@unimelb.edu.au.
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