Phase 2b, open-label, single-arm, multicenter pilot study of the efficacy, safety, and tolerability of dostarlimab in women with early-stage mismatch repair-deficient endometrioid endometrial adenocarcinoma.
Saved in:
| Title: | Phase 2b, open-label, single-arm, multicenter pilot study of the efficacy, safety, and tolerability of dostarlimab in women with early-stage mismatch repair-deficient endometrioid endometrial adenocarcinoma. |
|---|---|
| Authors: | Obermair A; Royal Brisbane and Women's Hospital Campus, UQ Centre for Clinical Research, The University of Queensland, Queensland Centre for Gynaecological Cancer (QCGC) Research, Herston, QLD, Australia. Electronic address: a.obermair@uq.edu.au., Gebski V; The University of Sydney, Faculty of Medicine and Health, NHMRC Clinical Trials Centre, Camperdown, NSW, Australia., Goh J; Cancer Care Services, Royal Brisbane and Women's Hospital, Herston, QLD, Australia., Kuchel A; Cancer Care Services, Royal Brisbane and Women's Hospital, Herston, QLD, Australia; University of Queensland, The School of Medicine, Herston, QLD, Australia., Brand A; Westmead Hospital, The Crown Princess Mary Cancer Centre, Westmead, NSW, Australia; Westmead Centre for Gynaecological Oncology, The University of Sydney, Camperdown, NSW, Australia., Mak B; The University of Sydney, Faculty of Medicine and Health, NHMRC Clinical Trials Centre, Camperdown, NSW, Australia; Westmead Hospital, The Crown Princess Mary Cancer Centre, Westmead, NSW, Australia., McNally O; Oncology and Dysplasia Service, The Royal Women's Hospital, Parkville, VIC, Australia; Department of Obstetrics and Gynaecology, The University of Melbourne, Parkville, VIC, Australia; Department of Medical Oncology, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia., Baxter E; Royal Brisbane and Women's Hospital Campus, UQ Centre for Clinical Research, The University of Queensland, Queensland Centre for Gynaecological Cancer (QCGC) Research, Herston, QLD, Australia., Jobling T; Monash University, Department of Obstetrics and Gynaecology, Clayton, VIC, Australia; Monash Health, Women's and Newborn Program, Clayton, VIC, Australia., Mileshkin L; Department of Medical Oncology, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia. |
| Source: | International journal of gynecological cancer : official journal of the International Gynecological Cancer Society [Int J Gynecol Cancer] 2025 Apr; Vol. 35 (4), pp. 101644. Date of Electronic Publication: 2025 Jan 16. |
| Publication Type: | Clinical Trial Protocol; Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: BMJ Country of Publication: United States NLM ID: 9111626 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-1438 (Electronic) Linking ISSN: 1048891X NLM ISO Abbreviation: Int J Gynecol Cancer Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
|---|---|
| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 39955187 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
| IllustrationInfo | |
| Items | – Name: Title Label: Title Group: Ti Data: Phase 2b, open-label, single-arm, multicenter pilot study of the efficacy, safety, and tolerability of dostarlimab in women with early-stage mismatch repair-deficient endometrioid endometrial adenocarcinoma. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Obermair+A%22">Obermair A</searchLink>; Royal Brisbane and Women's Hospital Campus, UQ Centre for Clinical Research, The University of Queensland, Queensland Centre for Gynaecological Cancer (QCGC) Research, Herston, QLD, Australia. Electronic address: a.obermair@uq.edu.au.<br /><searchLink fieldCode="AU" term="%22Gebski+V%22">Gebski V</searchLink>; The University of Sydney, Faculty of Medicine and Health, NHMRC Clinical Trials Centre, Camperdown, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Goh+J%22">Goh J</searchLink>; Cancer Care Services, Royal Brisbane and Women's Hospital, Herston, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Kuchel+A%22">Kuchel A</searchLink>; Cancer Care Services, Royal Brisbane and Women's Hospital, Herston, QLD, Australia; University of Queensland, The School of Medicine, Herston, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Brand+A%22">Brand A</searchLink>; Westmead Hospital, The Crown Princess Mary Cancer Centre, Westmead, NSW, Australia; Westmead Centre for Gynaecological Oncology, The University of Sydney, Camperdown, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Mak+B%22">Mak B</searchLink>; The University of Sydney, Faculty of Medicine and Health, NHMRC Clinical Trials Centre, Camperdown, NSW, Australia; Westmead Hospital, The Crown Princess Mary Cancer Centre, Westmead, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22McNally+O%22">McNally O</searchLink>; Oncology and Dysplasia Service, The Royal Women's Hospital, Parkville, VIC, Australia; Department of Obstetrics and Gynaecology, The University of Melbourne, Parkville, VIC, Australia; Department of Medical Oncology, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Baxter+E%22">Baxter E</searchLink>; Royal Brisbane and Women's Hospital Campus, UQ Centre for Clinical Research, The University of Queensland, Queensland Centre for Gynaecological Cancer (QCGC) Research, Herston, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Jobling+T%22">Jobling T</searchLink>; Monash University, Department of Obstetrics and Gynaecology, Clayton, VIC, Australia; Monash Health, Women's and Newborn Program, Clayton, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Mileshkin+L%22">Mileshkin L</searchLink>; Department of Medical Oncology, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%229111626%22">International journal of gynecological cancer : official journal of the International Gynecological Cancer Society</searchLink> [Int J Gynecol Cancer] 2025 Apr; Vol. 35 (4), pp. 101644. <i>Date of Electronic Publication: </i>2025 Jan 16. – Name: TypePub Label: Publication Type Group: TypPub Data: Clinical Trial Protocol; Journal Article; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BMJ%22">BMJ </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9111626 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1525-1438 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%221048891X%22">1048891X </searchLink><i>NLM ISO Abbreviation: </i>Int J Gynecol Cancer <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=39955187 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.ijgc.2025.101644 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 101644 Titles: – TitleFull: Phase 2b, open-label, single-arm, multicenter pilot study of the efficacy, safety, and tolerability of dostarlimab in women with early-stage mismatch repair-deficient endometrioid endometrial adenocarcinoma. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Obermair A – PersonEntity: Name: NameFull: Gebski V – PersonEntity: Name: NameFull: Goh J – PersonEntity: Name: NameFull: Kuchel A – PersonEntity: Name: NameFull: Brand A – PersonEntity: Name: NameFull: Mak B – PersonEntity: Name: NameFull: McNally O – PersonEntity: Name: NameFull: Baxter E – PersonEntity: Name: NameFull: Jobling T – PersonEntity: Name: NameFull: Mileshkin L IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 04 Text: 2025 Apr Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 1525-1438 Numbering: – Type: volume Value: 35 – Type: issue Value: 4 Titles: – TitleFull: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society Type: main |
| ResultId | 1 |
