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Immunological responses and clinical outcomes in dogs with osteosarcoma receiving standard therapy and a Listeria vaccine expressing HER2.

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Title: Immunological responses and clinical outcomes in dogs with osteosarcoma receiving standard therapy and a Listeria vaccine expressing HER2.
Authors: Mason NJ; Department of Pathobiology, University of Pennsylvania, School of Veterinary Medicine, Philadelphia, PA 19104, USA. Electronic address: nmason@vet.upenn.edu., Selmic L; Department of Veterinary Clinical Sciences, The Ohio State University College of Veterinary Medicine, Columbus, OH 43210, USA., Ruple A; Department of Population Health Sciences, Virginia Tech, Blacksburg, VA 24061, USA., London CA; Department of Clinical Sciences, Cummings School of Veterinary Medicine at Tufts University, North Grafton, MA 01536, USA., Barber L; Department of Clinical Sciences, Cummings School of Veterinary Medicine at Tufts University, North Grafton, MA 01536, USA., Weishaar K; Flint Animal Cancer Center, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80525, USA., Perry JA; CASTR Alliance, 22524 SE 64(th) Place, Suite 2258, Issaquah, WA 98027, USA., Mahoney J; Department of Clinical Sciences & Advanced Medicine, University of Pennsylvania, School of Veterinary Medicine, Philadelphia, PA 19104, USA., Flesner B; Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA., Bryan JN; Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA., Willcox JL; Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California, Davis, Davis, CA 95616, USA., Burton JH; Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California, Davis, Davis, CA 95616, USA., Vail DM; Department of Medical Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI 53706, USA., Kisseberth WC; Department of Veterinary Clinical Sciences, The Ohio State University College of Veterinary Medicine, Columbus, OH 43210, USA., Balkman CE; Department of Clinical Science, Cornell University College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA., McCleary-Wheeler AL; Department of Clinical Science, Cornell University College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA., Curran KM; Department of Clinical Sciences, Carlson College of Veterinary Medicine, Oregon State University, Corvallis, OR 43210, USA., Leeper H; Department of Clinical Sciences, Carlson College of Veterinary Medicine, Oregon State University, Corvallis, OR 43210, USA., Woods JP; Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, ON NWG 2W1, Canada., Mutsaers AJ; Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, ON NWG 2W1, Canada., Higginbotham ML; Department of Clinical Sciences, College of Veterinary Medicine, Kansas State University, Manhattan, KS 66502, USA., Wouda RM; Oncology Service, Veterinary Specialist Services, Underwood, QLD 4119, Australia., Wilson-Robles H; Ethos Discovery, 10435 Sorrento Valley Road, San Diego, CA 92121, USA., Dervisis N; College of Veterinary Medicine and Purdue Institute for Cancer Research, Purdue University, West Lafayette, IN 47907, USA., Saba C; Department of Small Animal Medicine & Surgery, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA., MacDonald-Dickinson VS; Department of Small Animal Clinical Sciences, University of Saskatchewan, Saskatoon, SK SN7 5B4, Canada., Hess PR; Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606, USA., Cherukuri A; Comparative Oncology Program, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA., Rotolo A; Department of Pathobiology, University of Pennsylvania, School of Veterinary Medicine, Philadelphia, PA 19104, USA., Beck JA; Comparative Oncology Program, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA., Patkar S; Comparative Oncology Program, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA; Artificial Intelligence Resource, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA., Mazcko C; Comparative Oncology Program, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA., LeBlanc AK; Comparative Oncology Program, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA.
Source: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2025 Apr 02; Vol. 33 (4), pp. 1674-1686. Date of Electronic Publication: 2025 Feb 15.
Publication Type: Clinical Trial, Veterinary; Journal Article; Multicenter Study
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 100890581 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-0024 (Electronic) Linking ISSN: 15250016 NLM ISO Abbreviation: Mol Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
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  Data: Immunological responses and clinical outcomes in dogs with osteosarcoma receiving standard therapy and a Listeria vaccine expressing HER2.
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  Data: <searchLink fieldCode="AU" term="%22Mason+NJ%22">Mason NJ</searchLink>; Department of Pathobiology, University of Pennsylvania, School of Veterinary Medicine, Philadelphia, PA 19104, USA. Electronic address: nmason@vet.upenn.edu.<br /><searchLink fieldCode="AU" term="%22Selmic+L%22">Selmic L</searchLink>; Department of Veterinary Clinical Sciences, The Ohio State University College of Veterinary Medicine, Columbus, OH 43210, USA.<br /><searchLink fieldCode="AU" term="%22Ruple+A%22">Ruple A</searchLink>; Department of Population Health Sciences, Virginia Tech, Blacksburg, VA 24061, USA.<br /><searchLink fieldCode="AU" term="%22London+CA%22">London CA</searchLink>; Department of Clinical Sciences, Cummings School of Veterinary Medicine at Tufts University, North Grafton, MA 01536, USA.<br /><searchLink fieldCode="AU" term="%22Barber+L%22">Barber L</searchLink>; Department of Clinical Sciences, Cummings School of Veterinary Medicine at Tufts University, North Grafton, MA 01536, USA.<br /><searchLink fieldCode="AU" term="%22Weishaar+K%22">Weishaar K</searchLink>; Flint Animal Cancer Center, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80525, USA.<br /><searchLink fieldCode="AU" term="%22Perry+JA%22">Perry JA</searchLink>; CASTR Alliance, 22524 SE 64(th) Place, Suite 2258, Issaquah, WA 98027, USA.<br /><searchLink fieldCode="AU" term="%22Mahoney+J%22">Mahoney J</searchLink>; Department of Clinical Sciences & Advanced Medicine, University of Pennsylvania, School of Veterinary Medicine, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Flesner+B%22">Flesner B</searchLink>; Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA.<br /><searchLink fieldCode="AU" term="%22Bryan+JN%22">Bryan JN</searchLink>; Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA.<br /><searchLink fieldCode="AU" term="%22Willcox+JL%22">Willcox JL</searchLink>; Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California, Davis, Davis, CA 95616, USA.<br /><searchLink fieldCode="AU" term="%22Burton+JH%22">Burton JH</searchLink>; Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California, Davis, Davis, CA 95616, USA.<br /><searchLink fieldCode="AU" term="%22Vail+DM%22">Vail DM</searchLink>; Department of Medical Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI 53706, USA.<br /><searchLink fieldCode="AU" term="%22Kisseberth+WC%22">Kisseberth WC</searchLink>; Department of Veterinary Clinical Sciences, The Ohio State University College of Veterinary Medicine, Columbus, OH 43210, USA.<br /><searchLink fieldCode="AU" term="%22Balkman+CE%22">Balkman CE</searchLink>; Department of Clinical Science, Cornell University College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA.<br /><searchLink fieldCode="AU" term="%22McCleary-Wheeler+AL%22">McCleary-Wheeler AL</searchLink>; Department of Clinical Science, Cornell University College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA.<br /><searchLink fieldCode="AU" term="%22Curran+KM%22">Curran KM</searchLink>; Department of Clinical Sciences, Carlson College of Veterinary Medicine, Oregon State University, Corvallis, OR 43210, USA.<br /><searchLink fieldCode="AU" term="%22Leeper+H%22">Leeper H</searchLink>; Department of Clinical Sciences, Carlson College of Veterinary Medicine, Oregon State University, Corvallis, OR 43210, USA.<br /><searchLink fieldCode="AU" term="%22Woods+JP%22">Woods JP</searchLink>; Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, ON NWG 2W1, Canada.<br /><searchLink fieldCode="AU" term="%22Mutsaers+AJ%22">Mutsaers AJ</searchLink>; Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, ON NWG 2W1, Canada.<br /><searchLink fieldCode="AU" term="%22Higginbotham+ML%22">Higginbotham ML</searchLink>; Department of Clinical Sciences, College of Veterinary Medicine, Kansas State University, Manhattan, KS 66502, USA.<br /><searchLink fieldCode="AU" term="%22Wouda+RM%22">Wouda RM</searchLink>; Oncology Service, Veterinary Specialist Services, Underwood, QLD 4119, Australia.<br /><searchLink fieldCode="AU" term="%22Wilson-Robles+H%22">Wilson-Robles H</searchLink>; Ethos Discovery, 10435 Sorrento Valley Road, San Diego, CA 92121, USA.<br /><searchLink fieldCode="AU" term="%22Dervisis+N%22">Dervisis N</searchLink>; College of Veterinary Medicine and Purdue Institute for Cancer Research, Purdue University, West Lafayette, IN 47907, USA.<br /><searchLink fieldCode="AU" term="%22Saba+C%22">Saba C</searchLink>; Department of Small Animal Medicine & Surgery, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA.<br /><searchLink fieldCode="AU" term="%22MacDonald-Dickinson+VS%22">MacDonald-Dickinson VS</searchLink>; Department of Small Animal Clinical Sciences, University of Saskatchewan, Saskatoon, SK SN7 5B4, Canada.<br /><searchLink fieldCode="AU" term="%22Hess+PR%22">Hess PR</searchLink>; Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606, USA.<br /><searchLink fieldCode="AU" term="%22Cherukuri+A%22">Cherukuri A</searchLink>; Comparative Oncology Program, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA.<br /><searchLink fieldCode="AU" term="%22Rotolo+A%22">Rotolo A</searchLink>; Department of Pathobiology, University of Pennsylvania, School of Veterinary Medicine, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Beck+JA%22">Beck JA</searchLink>; Comparative Oncology Program, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA.<br /><searchLink fieldCode="AU" term="%22Patkar+S%22">Patkar S</searchLink>; Comparative Oncology Program, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA; Artificial Intelligence Resource, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA.<br /><searchLink fieldCode="AU" term="%22Mazcko+C%22">Mazcko C</searchLink>; Comparative Oncology Program, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA.<br /><searchLink fieldCode="AU" term="%22LeBlanc+AK%22">LeBlanc AK</searchLink>; Comparative Oncology Program, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA.
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  Data: <searchLink fieldCode="JN" term="%22100890581%22">Molecular therapy : the journal of the American Society of Gene Therapy</searchLink> [Mol Ther] 2025 Apr 02; Vol. 33 (4), pp. 1674-1686. <i>Date of Electronic Publication: </i>2025 Feb 15.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cell+Press%22">Cell Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>100890581 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1525-0024 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215250016%22">15250016 </searchLink><i>NLM ISO Abbreviation: </i>Mol Ther <i>Subsets: </i>MEDLINE
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