Deep Learning-Based Signal Amplification of T1-Weighted Single-Dose Images Improves Metastasis Detection in Brain MRI.

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Title: Deep Learning-Based Signal Amplification of T1-Weighted Single-Dose Images Improves Metastasis Detection in Brain MRI.
Authors: Haase R; From the Department of Diagnostic and Interventional Neuroradiology, University Hospital Bonn, Bonn, Germany (R.H., E.K., Z.B., S.Z., A.-H.S., F.C.S., S.P., A.M.S., D.P., A.R., K.D.); Institute of Applied Mathematics, Rheinische Friedrich-Wilhelms-Universität Bonn, Bonn, Germany (T.P., A.E.); Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (D.P.); Division of Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany (D.P., H.-P.S.); Department of Diagnostic and Interventional Radiology With Nuclear Medicine, Thoraxklinik at University Hospital Heidelberg, Heidelberg, Germany (M.F.-D., K.S., G.H., C.P.H.); Department of Neuroradiology, Heidelberg University Hospital, Heidelberg, Germany (M.F.-D.); Department of Diagnostic and Interventional Radiology, University Hospital Heidelberg, Heidelberg, Germany (V.W., C.P.H.); Institute for Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, Essen, Germany (M.H., J.H., C.D.); Translational Lung Research Center Heidelberg (TLRC), Member of the German Center of Lung Research (DZL), Heidelberg, Germany (C.P.H.); Praxisnetz, Radiology and Nuclear Medicine, Bonn, Germany (M.V.); Department of Diagnostic and Interventional Radiology, University Hospital Bonn, Bonn, Germany (J.A.L.); German Center for Neurodegenerative Diseases (DZNE), Helmholtz Association of German Research Centers, Bonn, Germany (A.R., K.D.); and Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA (K.D.)., Pinetz T, Kobler E, Bendella Z, Zülow S, Schievelkamp AH, Schmeel FC, Panahabadi S, Stylianou AM, Paech D, Foltyn-Dumitru M, Wagner V, Schlamp K, Heussel G, Holtkamp M, Heussel CP, Vahlensieck M, Luetkens JA, Schlemmer HP, Haubold J, Radbruch A, Effland A, Deuschl C, Deike K
Source: Investigative radiology [Invest Radiol] 2025 Aug 01; Vol. 60 (8), pp. 543-551. Date of Electronic Publication: 2025 Feb 18.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0045377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1536-0210 (Electronic) Linking ISSN: 00209996 NLM ISO Abbreviation: Invest Radiol Subsets: MEDLINE
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  Data: Deep Learning-Based Signal Amplification of T1-Weighted Single-Dose Images Improves Metastasis Detection in Brain MRI.
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  Data: <searchLink fieldCode="AU" term="%22Haase+R%22">Haase R</searchLink>; From the Department of Diagnostic and Interventional Neuroradiology, University Hospital Bonn, Bonn, Germany (R.H., E.K., Z.B., S.Z., A.-H.S., F.C.S., S.P., A.M.S., D.P., A.R., K.D.); Institute of Applied Mathematics, Rheinische Friedrich-Wilhelms-Universität Bonn, Bonn, Germany (T.P., A.E.); Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (D.P.); Division of Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany (D.P., H.-P.S.); Department of Diagnostic and Interventional Radiology With Nuclear Medicine, Thoraxklinik at University Hospital Heidelberg, Heidelberg, Germany (M.F.-D., K.S., G.H., C.P.H.); Department of Neuroradiology, Heidelberg University Hospital, Heidelberg, Germany (M.F.-D.); Department of Diagnostic and Interventional Radiology, University Hospital Heidelberg, Heidelberg, Germany (V.W., C.P.H.); Institute for Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, Essen, Germany (M.H., J.H., C.D.); Translational Lung Research Center Heidelberg (TLRC), Member of the German Center of Lung Research (DZL), Heidelberg, Germany (C.P.H.); Praxisnetz, Radiology and Nuclear Medicine, Bonn, Germany (M.V.); Department of Diagnostic and Interventional Radiology, University Hospital Bonn, Bonn, Germany (J.A.L.); German Center for Neurodegenerative Diseases (DZNE), Helmholtz Association of German Research Centers, Bonn, Germany (A.R., K.D.); and Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA (K.D.).<br /><searchLink fieldCode="AU" term="%22Pinetz+T%22">Pinetz T</searchLink><br /><searchLink fieldCode="AU" term="%22Kobler+E%22">Kobler E</searchLink><br /><searchLink fieldCode="AU" term="%22Bendella+Z%22">Bendella Z</searchLink><br /><searchLink fieldCode="AU" term="%22Zülow+S%22">Zülow S</searchLink><br /><searchLink fieldCode="AU" term="%22Schievelkamp+AH%22">Schievelkamp AH</searchLink><br /><searchLink fieldCode="AU" term="%22Schmeel+FC%22">Schmeel FC</searchLink><br /><searchLink fieldCode="AU" term="%22Panahabadi+S%22">Panahabadi S</searchLink><br /><searchLink fieldCode="AU" term="%22Stylianou+AM%22">Stylianou AM</searchLink><br /><searchLink fieldCode="AU" term="%22Paech+D%22">Paech D</searchLink><br /><searchLink fieldCode="AU" term="%22Foltyn-Dumitru+M%22">Foltyn-Dumitru M</searchLink><br /><searchLink fieldCode="AU" term="%22Wagner+V%22">Wagner V</searchLink><br /><searchLink fieldCode="AU" term="%22Schlamp+K%22">Schlamp K</searchLink><br /><searchLink fieldCode="AU" term="%22Heussel+G%22">Heussel G</searchLink><br /><searchLink fieldCode="AU" term="%22Holtkamp+M%22">Holtkamp M</searchLink><br /><searchLink fieldCode="AU" term="%22Heussel+CP%22">Heussel CP</searchLink><br /><searchLink fieldCode="AU" term="%22Vahlensieck+M%22">Vahlensieck M</searchLink><br /><searchLink fieldCode="AU" term="%22Luetkens+JA%22">Luetkens JA</searchLink><br /><searchLink fieldCode="AU" term="%22Schlemmer+HP%22">Schlemmer HP</searchLink><br /><searchLink fieldCode="AU" term="%22Haubold+J%22">Haubold J</searchLink><br /><searchLink fieldCode="AU" term="%22Radbruch+A%22">Radbruch A</searchLink><br /><searchLink fieldCode="AU" term="%22Effland+A%22">Effland A</searchLink><br /><searchLink fieldCode="AU" term="%22Deuschl+C%22">Deuschl C</searchLink><br /><searchLink fieldCode="AU" term="%22Deike+K%22">Deike K</searchLink>
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  Data: <searchLink fieldCode="JN" term="%220045377%22">Investigative radiology</searchLink> [Invest Radiol] 2025 Aug 01; Vol. 60 (8), pp. 543-551. <i>Date of Electronic Publication: </i>2025 Feb 18.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Lippincott+Williams+%26+Wilkins%22">Lippincott Williams & Wilkins </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0045377 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1536-0210 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200209996%22">00209996 </searchLink><i>NLM ISO Abbreviation: </i>Invest Radiol <i>Subsets: </i>MEDLINE
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        Value: 10.1097/RLI.0000000000001166
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