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Effect of sotagliflozin on major adverse cardiovascular events: a prespecified secondary analysis of the SCORED randomised trial.

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Title: Effect of sotagliflozin on major adverse cardiovascular events: a prespecified secondary analysis of the SCORED randomised trial.
Authors: Aggarwal R; Brigham and Women's Hospital Heart and Vascular Center, Harvard Medical School, Boston, MA, USA., Bhatt DL; Mount Sinai Fuster Heart Hospital, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address: dlbhattmd@post.harvard.edu., Szarek M; Mount Sinai Fuster Heart Hospital, Icahn School of Medicine at Mount Sinai, New York, NY, USA; CPC Clinical Research and University of Colorado Anschutz Medical Campus, Aurora, CO, USA; State University of New York Downstate School of Public Health, Brooklyn, NY, USA., Cannon CP; Brigham and Women's Hospital Heart and Vascular Center, Harvard Medical School, Boston, MA, USA., Leiter LA; Li Ka Shing Knowledge Institute, St Michael's Hospital, University of Toronto, Toronto, ON, Canada., Inzucchi SE; Yale School of Medicine, New Haven, CT, USA., Lopes RD; Duke University School of Medicine, Durham, NC, USA., McGuire DK; University of Texas Southwestern Medical Center and Parkland Health, Dallas, Texas, USA., Lewis JB; Vanderbilt University Medical Center, Nashville, Tennessee, USA., Riddle MC; Oregon Health and Science University, Portland, OR, USA., Davies MJ; Lexicon Pharmaceuticals, The Woodlands, TX, USA., Banks P; Lexicon Pharmaceuticals, The Woodlands, TX, USA., Carroll AK; Lexicon Pharmaceuticals, The Woodlands, TX, USA., Scirica BM; TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Ray KK; Department of Primary Care and Public Health, Imperial College London, London, UK., Kosiborod MN; Saint Luke's Mid America Heart Institute, University of Missouri-Kansas City, Kansas City, MO, USA., Cherney DZI; University Health Network, Toronto General Hospital Research Institute, University of Toronto, Toronto, ON, Canada., Udell JA; Women's College Hospital and Peter Munk Cardiac Centre, Toronto General Hospital, University of Toronto, ON, Canada., Verma S; Li Ka Shing Knowledge Institute, St Michael's Hospital, University of Toronto, Toronto, ON, Canada., Mason RP; Brigham and Women's Hospital Heart and Vascular Center, Harvard Medical School, Boston, MA, USA; Elucida Research, Beverly, MA, USA., Pitt B; University of Michigan, Ann Arbor, MI, USA., Steg PG; Université Paris-Cité, INSERM U1148 and AP-HP Hôpital Bichat, Paris, France; French Alliance for Cardiovascular Trials, Paris, France.
Source: The lancet. Diabetes & endocrinology [Lancet Diabetes Endocrinol] 2025 Apr; Vol. 13 (4), pp. 321-332. Date of Electronic Publication: 2025 Feb 14.
Publication Type: Clinical Trial, Phase III; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
Journal Info: Publisher: The Lancet, Diabetes & Endocrinology Country of Publication: England NLM ID: 101618821 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-8595 (Electronic) Linking ISSN: 22138587 NLM ISO Abbreviation: Lancet Diabetes Endocrinol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Effect of sotagliflozin on major adverse cardiovascular events: a prespecified secondary analysis of the SCORED randomised trial.
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  Data: <searchLink fieldCode="AU" term="%22Aggarwal+R%22">Aggarwal R</searchLink>; Brigham and Women's Hospital Heart and Vascular Center, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Bhatt+DL%22">Bhatt DL</searchLink>; Mount Sinai Fuster Heart Hospital, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address: dlbhattmd@post.harvard.edu.<br /><searchLink fieldCode="AU" term="%22Szarek+M%22">Szarek M</searchLink>; Mount Sinai Fuster Heart Hospital, Icahn School of Medicine at Mount Sinai, New York, NY, USA; CPC Clinical Research and University of Colorado Anschutz Medical Campus, Aurora, CO, USA; State University of New York Downstate School of Public Health, Brooklyn, NY, USA.<br /><searchLink fieldCode="AU" term="%22Cannon+CP%22">Cannon CP</searchLink>; Brigham and Women's Hospital Heart and Vascular Center, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Leiter+LA%22">Leiter LA</searchLink>; Li Ka Shing Knowledge Institute, St Michael's Hospital, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Inzucchi+SE%22">Inzucchi SE</searchLink>; Yale School of Medicine, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Lopes+RD%22">Lopes RD</searchLink>; Duke University School of Medicine, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22McGuire+DK%22">McGuire DK</searchLink>; University of Texas Southwestern Medical Center and Parkland Health, Dallas, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Lewis+JB%22">Lewis JB</searchLink>; Vanderbilt University Medical Center, Nashville, Tennessee, USA.<br /><searchLink fieldCode="AU" term="%22Riddle+MC%22">Riddle MC</searchLink>; Oregon Health and Science University, Portland, OR, USA.<br /><searchLink fieldCode="AU" term="%22Davies+MJ%22">Davies MJ</searchLink>; Lexicon Pharmaceuticals, The Woodlands, TX, USA.<br /><searchLink fieldCode="AU" term="%22Banks+P%22">Banks P</searchLink>; Lexicon Pharmaceuticals, The Woodlands, TX, USA.<br /><searchLink fieldCode="AU" term="%22Carroll+AK%22">Carroll AK</searchLink>; Lexicon Pharmaceuticals, The Woodlands, TX, USA.<br /><searchLink fieldCode="AU" term="%22Scirica+BM%22">Scirica BM</searchLink>; TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Ray+KK%22">Ray KK</searchLink>; Department of Primary Care and Public Health, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Kosiborod+MN%22">Kosiborod MN</searchLink>; Saint Luke's Mid America Heart Institute, University of Missouri-Kansas City, Kansas City, MO, USA.<br /><searchLink fieldCode="AU" term="%22Cherney+DZI%22">Cherney DZI</searchLink>; University Health Network, Toronto General Hospital Research Institute, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Udell+JA%22">Udell JA</searchLink>; Women's College Hospital and Peter Munk Cardiac Centre, Toronto General Hospital, University of Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Verma+S%22">Verma S</searchLink>; Li Ka Shing Knowledge Institute, St Michael's Hospital, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Mason+RP%22">Mason RP</searchLink>; Brigham and Women's Hospital Heart and Vascular Center, Harvard Medical School, Boston, MA, USA; Elucida Research, Beverly, MA, USA.<br /><searchLink fieldCode="AU" term="%22Pitt+B%22">Pitt B</searchLink>; University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Steg+PG%22">Steg PG</searchLink>; Université Paris-Cité, INSERM U1148 and AP-HP Hôpital Bichat, Paris, France; French Alliance for Cardiovascular Trials, Paris, France.
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  Data: <searchLink fieldCode="JN" term="%22101618821%22">The lancet. Diabetes & endocrinology</searchLink> [Lancet Diabetes Endocrinol] 2025 Apr; Vol. 13 (4), pp. 321-332. <i>Date of Electronic Publication: </i>2025 Feb 14.
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  Data: Clinical Trial, Phase III; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22The+Lancet%2C+Diabetes+%26+Endocrinology%22">The Lancet, Diabetes & Endocrinology </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101618821 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2213-8595 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2222138587%22">22138587 </searchLink><i>NLM ISO Abbreviation: </i>Lancet Diabetes Endocrinol <i>Subsets: </i>MEDLINE
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