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Whole genome sequencing of hepatitis B virus using tiled amplicon (HEPTILE) and probe based enrichment on Illumina and Nanopore platforms.

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Title: Whole genome sequencing of hepatitis B virus using tiled amplicon (HEPTILE) and probe based enrichment on Illumina and Nanopore platforms.
Authors: Lumley SF; Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Department of Infectious Diseases and Microbiology, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford, UK., Kent C; Institute of Microbiology and Infection, University of Birmingham, Birmingham, UK., Jennings D; Nuffield Department of Medicine, University of Oxford, Oxford, UK., Chai H; Nuffield Department of Medicine, University of Oxford, Oxford, UK., Airey G; Nuffield Department of Medicine, University of Oxford, Oxford, UK., Waddilove E; The Francis Crick Institute, London, UK., Delphin M; The Francis Crick Institute, London, UK., Trebes A; Nuffield Department of Medicine, Centre for Human Genomics, University of Oxford, Oxford, UK.; Genewiz UK Ltd, Azenta Life Sciences, Stratton Court, Abingdon, UK., McNaughton AL; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Mohammed KS; The Francis Crick Institute, London, UK., Wilkinson SAJ; Institute of Microbiology and Infection, University of Birmingham, Birmingham, UK., Wu Y; Nuffield Department of Medicine, Centre for Human Genomics, University of Oxford, Oxford, UK., MacIntyre-Cockett G; Nuffield Department of Medicine, Centre for Human Genomics, University of Oxford, Oxford, UK., Kimono B; MRC/UVRI & LSHTM Uganda Research Unit, Entebbe, Uganda., Mbonye KM; MRC/UVRI & LSHTM Uganda Research Unit, Entebbe, Uganda., Ojambo K; MRC/UVRI & LSHTM Uganda Research Unit, Entebbe, Uganda., Maponga TG; Division of Medical Virology, Stellenbosch University Faculty of Medicine and Health Sciences and National Health Laboratory Service Tygerberg Business Unit, Cape Town, South Africa., Tan CCS; The Francis Crick Institute, London, UK., de Lara C; Nuffield Department of Medicine, University of Oxford, Oxford, UK., Martin J; Department of Infectious Diseases and Microbiology, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford, UK., Campbell J; The Francis Crick Institute, London, UK., Van Schalkwyk M; Division of Infectious Diseases, Department of Medicine, Stellenbosch University and Tygerberg Hospital, Cape Town, South Africa., Goedhals D; University of the Free State, Bloemfontein, South Africa.; PathCare, Pretoria, South Africa., Newton R; MRC/UVRI & LSHTM Uganda Research Unit, Entebbe, Uganda.; Department of Health Sciences, University of York, York, UK., Barnes E; Nuffield Department of Medicine, University of Oxford, Oxford, UK., Loman NJ; Institute of Microbiology and Infection, University of Birmingham, Birmingham, UK., Piazza P; Nuffield Department of Medicine, Centre for Human Genomics, University of Oxford, Oxford, UK., Quick J; Institute of Microbiology and Infection, University of Birmingham, Birmingham, UK., Ansari MA; Nuffield Department of Medicine, University of Oxford, Oxford, UK. azim.ansari@ndm.ox.ac.uk., Matthews PC; The Francis Crick Institute, London, UK. philippa.matthews@crick.ac.uk.; Division of Infection and Immunity, University College London, London, UK. philippa.matthews@crick.ac.uk.; Department of Infection, University College London Hospitals, London, UK. philippa.matthews@crick.ac.uk.
Source: Scientific reports [Sci Rep] 2025 Feb 17; Vol. 15 (1), pp. 5795. Date of Electronic Publication: 2025 Feb 17.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
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  Data: Whole genome sequencing of hepatitis B virus using tiled amplicon (HEPTILE) and probe based enrichment on Illumina and Nanopore platforms.
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  Data: <searchLink fieldCode="AU" term="%22Lumley+SF%22">Lumley SF</searchLink>; Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Department of Infectious Diseases and Microbiology, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Kent+C%22">Kent C</searchLink>; Institute of Microbiology and Infection, University of Birmingham, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Jennings+D%22">Jennings D</searchLink>; Nuffield Department of Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Chai+H%22">Chai H</searchLink>; Nuffield Department of Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Airey+G%22">Airey G</searchLink>; Nuffield Department of Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Waddilove+E%22">Waddilove E</searchLink>; The Francis Crick Institute, London, UK.<br /><searchLink fieldCode="AU" term="%22Delphin+M%22">Delphin M</searchLink>; The Francis Crick Institute, London, UK.<br /><searchLink fieldCode="AU" term="%22Trebes+A%22">Trebes A</searchLink>; Nuffield Department of Medicine, Centre for Human Genomics, University of Oxford, Oxford, UK.; Genewiz UK Ltd, Azenta Life Sciences, Stratton Court, Abingdon, UK.<br /><searchLink fieldCode="AU" term="%22McNaughton+AL%22">McNaughton AL</searchLink>; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Mohammed+KS%22">Mohammed KS</searchLink>; The Francis Crick Institute, London, UK.<br /><searchLink fieldCode="AU" term="%22Wilkinson+SAJ%22">Wilkinson SAJ</searchLink>; Institute of Microbiology and Infection, University of Birmingham, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Wu+Y%22">Wu Y</searchLink>; Nuffield Department of Medicine, Centre for Human Genomics, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22MacIntyre-Cockett+G%22">MacIntyre-Cockett G</searchLink>; Nuffield Department of Medicine, Centre for Human Genomics, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Kimono+B%22">Kimono B</searchLink>; MRC/UVRI & LSHTM Uganda Research Unit, Entebbe, Uganda.<br /><searchLink fieldCode="AU" term="%22Mbonye+KM%22">Mbonye KM</searchLink>; MRC/UVRI & LSHTM Uganda Research Unit, Entebbe, Uganda.<br /><searchLink fieldCode="AU" term="%22Ojambo+K%22">Ojambo K</searchLink>; MRC/UVRI & LSHTM Uganda Research Unit, Entebbe, Uganda.<br /><searchLink fieldCode="AU" term="%22Maponga+TG%22">Maponga TG</searchLink>; Division of Medical Virology, Stellenbosch University Faculty of Medicine and Health Sciences and National Health Laboratory Service Tygerberg Business Unit, Cape Town, South Africa.<br /><searchLink fieldCode="AU" term="%22Tan+CCS%22">Tan CCS</searchLink>; The Francis Crick Institute, London, UK.<br /><searchLink fieldCode="AU" term="%22de+Lara+C%22">de Lara C</searchLink>; Nuffield Department of Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Martin+J%22">Martin J</searchLink>; Department of Infectious Diseases and Microbiology, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Campbell+J%22">Campbell J</searchLink>; The Francis Crick Institute, London, UK.<br /><searchLink fieldCode="AU" term="%22Van+Schalkwyk+M%22">Van Schalkwyk M</searchLink>; Division of Infectious Diseases, Department of Medicine, Stellenbosch University and Tygerberg Hospital, Cape Town, South Africa.<br /><searchLink fieldCode="AU" term="%22Goedhals+D%22">Goedhals D</searchLink>; University of the Free State, Bloemfontein, South Africa.; PathCare, Pretoria, South Africa.<br /><searchLink fieldCode="AU" term="%22Newton+R%22">Newton R</searchLink>; MRC/UVRI & LSHTM Uganda Research Unit, Entebbe, Uganda.; Department of Health Sciences, University of York, York, UK.<br /><searchLink fieldCode="AU" term="%22Barnes+E%22">Barnes E</searchLink>; Nuffield Department of Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Loman+NJ%22">Loman NJ</searchLink>; Institute of Microbiology and Infection, University of Birmingham, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Piazza+P%22">Piazza P</searchLink>; Nuffield Department of Medicine, Centre for Human Genomics, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Quick+J%22">Quick J</searchLink>; Institute of Microbiology and Infection, University of Birmingham, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Ansari+MA%22">Ansari MA</searchLink>; Nuffield Department of Medicine, University of Oxford, Oxford, UK. azim.ansari@ndm.ox.ac.uk.<br /><searchLink fieldCode="AU" term="%22Matthews+PC%22">Matthews PC</searchLink>; The Francis Crick Institute, London, UK. philippa.matthews@crick.ac.uk.; Division of Infection and Immunity, University College London, London, UK. philippa.matthews@crick.ac.uk.; Department of Infection, University College London Hospitals, London, UK. philippa.matthews@crick.ac.uk.
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