Tumor-immune partitioning and clustering algorithm for identifying tumor-immune cell spatial interaction signatures within the tumor microenvironment.
Saved in:
| Title: | Tumor-immune partitioning and clustering algorithm for identifying tumor-immune cell spatial interaction signatures within the tumor microenvironment. |
|---|---|
| Authors: | Lau MC; Bioinformatics Institute (BII), Agency for Science, Technology and Research (A* STAR), Singapore, Republic of Singapore.; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A* STAR), Singapore, Republic of Singapore.; Department of Pathology, Program in MPE Molecular Pathological Epidemiology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America., Borowsky J; Conjoint Gastroenterology Department, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia., Väyrynen JP; Department of Pathology, Program in MPE Molecular Pathological Epidemiology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts, United States of America.; Cancer and Translational Medicine Research Unit, Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland., Haruki K; Department of Pathology, Program in MPE Molecular Pathological Epidemiology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.; Department of Surgery, The Jikei University School of Medicine, Tokyo, Japan., Zhao M; Department of Pathology, Program in MPE Molecular Pathological Epidemiology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America., Dias Costa A; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts, United States of America., Gu S; Department of Pathology, Program in MPE Molecular Pathological Epidemiology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America., da Silva A; Department of Pathology, Program in MPE Molecular Pathological Epidemiology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America., Ugai T; Department of Pathology, Program in MPE Molecular Pathological Epidemiology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States of America., Arima K; Department of Pathology, Program in MPE Molecular Pathological Epidemiology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America., Nguyen MN; Bioinformatics Institute (BII), Agency for Science, Technology and Research (A* STAR), Singapore, Republic of Singapore., Takashima Y; Department of Pathology, Program in MPE Molecular Pathological Epidemiology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts, United States of America., Yeong J; Division of Pathology, Singapore General Hospital, Singapore, Republic of Singapore.; Integrative Biology for Theranostics, Institute of Molecular Cell Biology, Agency of Science, Technology and Research (A* STAR), Singapore, Republic of Singapore., Tai D; Division of Medical Oncology, National Cancer Centre Singapore, Singapore, Republic of Singapore.; Duke NUS Medical School, Singapore, Republic of Singapore., Hamada T; Department of Pathology, Program in MPE Molecular Pathological Epidemiology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America., Lennerz JK; BostonGene; Waltham, Boston, Massachusetts, United States of America., Fuchs CS; Genentech, South San Francisco, California, United States of America., Wu CJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America.; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.; Cancer Vaccine Center, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America., Meyerhardt JA; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts, United States of America., Ogino S; Department of Pathology, Program in MPE Molecular Pathological Epidemiology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States of America.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America.; Cancer Immunology and Cancer Epidemiology Programs, Dana-Farber Harvard Cancer Center, Boston, Massachusetts, United States of America., Nowak JA; Department of Pathology, Program in MPE Molecular Pathological Epidemiology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts, United States of America. |
| Source: | PLoS computational biology [PLoS Comput Biol] 2025 Feb 18; Vol. 21 (2), pp. e1012707. Date of Electronic Publication: 2025 Feb 18 (Print Publication: 2025). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238922 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7358 (Electronic) Linking ISSN: 1553734X NLM ISO Abbreviation: PLoS Comput Biol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
|---|---|
| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 39965007 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
| IllustrationInfo | |
| Items | – Name: Title Label: Title Group: Ti Data: Tumor-immune partitioning and clustering algorithm for identifying tumor-immune cell spatial interaction signatures within the tumor microenvironment. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Lau+MC%22">Lau MC</searchLink>; Bioinformatics Institute (BII), Agency for Science, Technology and Research (A* STAR), Singapore, Republic of Singapore.; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A* STAR), Singapore, Republic of Singapore.; Department of Pathology, Program in MPE Molecular Pathological Epidemiology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.<br /><searchLink fieldCode="AU" term="%22Borowsky+J%22">Borowsky J</searchLink>; Conjoint Gastroenterology Department, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22Väyrynen+JP%22">Väyrynen JP</searchLink>; Department of Pathology, Program in MPE Molecular Pathological Epidemiology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts, United States of America.; Cancer and Translational Medicine Research Unit, Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland.<br /><searchLink fieldCode="AU" term="%22Haruki+K%22">Haruki K</searchLink>; Department of Pathology, Program in MPE Molecular Pathological Epidemiology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.; Department of Surgery, The Jikei University School of Medicine, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Zhao+M%22">Zhao M</searchLink>; Department of Pathology, Program in MPE Molecular Pathological Epidemiology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.<br /><searchLink fieldCode="AU" term="%22Dias+Costa+A%22">Dias Costa A</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts, United States of America.<br /><searchLink fieldCode="AU" term="%22Gu+S%22">Gu S</searchLink>; Department of Pathology, Program in MPE Molecular Pathological Epidemiology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.<br /><searchLink fieldCode="AU" term="%22da+Silva+A%22">da Silva A</searchLink>; Department of Pathology, Program in MPE Molecular Pathological Epidemiology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.<br /><searchLink fieldCode="AU" term="%22Ugai+T%22">Ugai T</searchLink>; Department of Pathology, Program in MPE Molecular Pathological Epidemiology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States of America.<br /><searchLink fieldCode="AU" term="%22Arima+K%22">Arima K</searchLink>; Department of Pathology, Program in MPE Molecular Pathological Epidemiology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.<br /><searchLink fieldCode="AU" term="%22Nguyen+MN%22">Nguyen MN</searchLink>; Bioinformatics Institute (BII), Agency for Science, Technology and Research (A* STAR), Singapore, Republic of Singapore.<br /><searchLink fieldCode="AU" term="%22Takashima+Y%22">Takashima Y</searchLink>; Department of Pathology, Program in MPE Molecular Pathological Epidemiology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts, United States of America.<br /><searchLink fieldCode="AU" term="%22Yeong+J%22">Yeong J</searchLink>; Division of Pathology, Singapore General Hospital, Singapore, Republic of Singapore.; Integrative Biology for Theranostics, Institute of Molecular Cell Biology, Agency of Science, Technology and Research (A* STAR), Singapore, Republic of Singapore.<br /><searchLink fieldCode="AU" term="%22Tai+D%22">Tai D</searchLink>; Division of Medical Oncology, National Cancer Centre Singapore, Singapore, Republic of Singapore.; Duke NUS Medical School, Singapore, Republic of Singapore.<br /><searchLink fieldCode="AU" term="%22Hamada+T%22">Hamada T</searchLink>; Department of Pathology, Program in MPE Molecular Pathological Epidemiology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.<br /><searchLink fieldCode="AU" term="%22Lennerz+JK%22">Lennerz JK</searchLink>; BostonGene; Waltham, Boston, Massachusetts, United States of America.<br /><searchLink fieldCode="AU" term="%22Fuchs+CS%22">Fuchs CS</searchLink>; Genentech, South San Francisco, California, United States of America.<br /><searchLink fieldCode="AU" term="%22Wu+CJ%22">Wu CJ</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America.; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.; Cancer Vaccine Center, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America.<br /><searchLink fieldCode="AU" term="%22Meyerhardt+JA%22">Meyerhardt JA</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts, United States of America.<br /><searchLink fieldCode="AU" term="%22Ogino+S%22">Ogino S</searchLink>; Department of Pathology, Program in MPE Molecular Pathological Epidemiology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States of America.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America.; Cancer Immunology and Cancer Epidemiology Programs, Dana-Farber Harvard Cancer Center, Boston, Massachusetts, United States of America.<br /><searchLink fieldCode="AU" term="%22Nowak+JA%22">Nowak JA</searchLink>; Department of Pathology, Program in MPE Molecular Pathological Epidemiology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts, United States of America. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101238922%22">PLoS computational biology</searchLink> [PLoS Comput Biol] 2025 Feb 18; Vol. 21 (2), pp. e1012707. <i>Date of Electronic Publication: </i>2025 Feb 18 (<i>Print Publication: </i>2025). – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Public+Library+of+Science%22">Public Library of Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101238922 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1553-7358 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%221553734X%22">1553734X </searchLink><i>NLM ISO Abbreviation: </i>PLoS Comput Biol <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=39965007 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1371/journal.pcbi.1012707 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: e1012707 Titles: – TitleFull: Tumor-immune partitioning and clustering algorithm for identifying tumor-immune cell spatial interaction signatures within the tumor microenvironment. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Lau MC – PersonEntity: Name: NameFull: Borowsky J – PersonEntity: Name: NameFull: Väyrynen JP – PersonEntity: Name: NameFull: Haruki K – PersonEntity: Name: NameFull: Zhao M – PersonEntity: Name: NameFull: Dias Costa A – PersonEntity: Name: NameFull: Gu S – PersonEntity: Name: NameFull: da Silva A – PersonEntity: Name: NameFull: Ugai T – PersonEntity: Name: NameFull: Arima K – PersonEntity: Name: NameFull: Nguyen MN – PersonEntity: Name: NameFull: Takashima Y – PersonEntity: Name: NameFull: Yeong J – PersonEntity: Name: NameFull: Tai D – PersonEntity: Name: NameFull: Hamada T – PersonEntity: Name: NameFull: Lennerz JK – PersonEntity: Name: NameFull: Fuchs CS – PersonEntity: Name: NameFull: Wu CJ – PersonEntity: Name: NameFull: Meyerhardt JA – PersonEntity: Name: NameFull: Ogino S – PersonEntity: Name: NameFull: Nowak JA IsPartOfRelationships: – BibEntity: Dates: – D: 18 M: 02 Text: 2025 Feb 18 Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 1553-7358 Numbering: – Type: volume Value: 21 – Type: issue Value: 2 Titles: – TitleFull: PLoS computational biology Type: main |
| ResultId | 1 |
