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Large-scale genome-wide association analyses identify novel genetic loci and mechanisms in hypertrophic cardiomyopathy.

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Title: Large-scale genome-wide association analyses identify novel genetic loci and mechanisms in hypertrophic cardiomyopathy.
Authors: Tadros R; Cardiovascular Genetics Centre and Research Centre, Montreal Heart Institute, Montreal, Quebec, Canada. rafik.tadros@umontreal.ca.; Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada. rafik.tadros@umontreal.ca.; Department of Experimental Cardiology, Amsterdam Cardiovascular Sciences, University of Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands. rafik.tadros@umontreal.ca., Zheng SL; National Heart and Lung Institute, Imperial College London, London, UK.; MRC Laboratory of Medical Sciences, Imperial College London, London, UK.; Royal Brompton and Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK., Grace C; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK., Jordà P; Cardiovascular Genetics Centre and Research Centre, Montreal Heart Institute, Montreal, Quebec, Canada.; Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada., Francis C; National Heart and Lung Institute, Imperial College London, London, UK.; Royal Brompton and Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK., West DM; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK., Jurgens SJ; Department of Experimental Cardiology, Amsterdam Cardiovascular Sciences, University of Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands.; Cardiovascular Disease Initiative, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Thomson KL; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK.; Oxford Genetics Laboratories, Churchill Hospital, Oxford, UK., Harper AR; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK., Ormondroyd E; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK., Xu X; MRC Laboratory of Medical Sciences, Imperial College London, London, UK., Theotokis PI; National Heart and Lung Institute, Imperial College London, London, UK.; MRC Laboratory of Medical Sciences, Imperial College London, London, UK.; Royal Brompton and Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK., Buchan RJ; National Heart and Lung Institute, Imperial College London, London, UK.; MRC Laboratory of Medical Sciences, Imperial College London, London, UK.; Royal Brompton and Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK., McGurk KA; National Heart and Lung Institute, Imperial College London, London, UK.; MRC Laboratory of Medical Sciences, Imperial College London, London, UK., Mazzarotto F; National Heart and Lung Institute, Imperial College London, London, UK.; Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy., Boschi B; Genetics Unit, Careggi University Hospital, Florence, Italy., Pelo E; Genetics Unit, Careggi University Hospital, Florence, Italy., Lee M; National Heart and Lung Institute, Imperial College London, London, UK., Noseda M; National Heart and Lung Institute, Imperial College London, London, UK., Varnava A; National Heart and Lung Institute, Imperial College London, London, UK.; Imperial College Healthcare NHS Trust, Imperial College London, London, UK., Vermeer AMC; Department of Experimental Cardiology, Amsterdam Cardiovascular Sciences, University of Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands.; Department of Clinical Genetics, University of Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands.; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart (ERN GUARD-HEART), Amsterdam, the Netherlands., Walsh R; Department of Experimental Cardiology, Amsterdam Cardiovascular Sciences, University of Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands., Amin AS; Department of Experimental Cardiology, Amsterdam Cardiovascular Sciences, University of Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands.; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart (ERN GUARD-HEART), Amsterdam, the Netherlands.; Department of Clinical Cardiology, Amsterdam Cardiovascular Sciences, University of Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands., van Slegtenhorst MA; Department of Clinical Genetics, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, the Netherlands., Roslin NM; Program in Genetics and Genome Biology and The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, Ontario, Canada., Strug LJ; Program in Genetics and Genome Biology and The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, Ontario, Canada.; Departments of Statistical Sciences and Computer Science, University of Toronto, Toronto, Ontario, Canada.; Division of Biostatistics, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada., Salvi E; Neuroalgology Unit, Fondazione IRCCS Istituto Neurologico 'Carlo Besta', Milan, Italy., Lanzani C; Genomics of Renal Diseases and Hypertension Unit and Nephrology Operative Unit, IRCCS San Raffaele Hospital, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy., de Marvao A; MRC Laboratory of Medical Sciences, Imperial College London, London, UK.; King's College London, London, UK., Roberts JD; Department of Medicine, Section of Cardiac Electrophysiology, Division of Cardiology, Western University, London, Ontario, Canada., Tremblay-Gravel M; Cardiovascular Genetics Centre and Research Centre, Montreal Heart Institute, Montreal, Quebec, Canada.; Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada., Giraldeau G; Cardiovascular Genetics Centre and Research Centre, Montreal Heart Institute, Montreal, Quebec, Canada.; Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada., Cadrin-Tourigny J; Cardiovascular Genetics Centre and Research Centre, Montreal Heart Institute, Montreal, Quebec, Canada.; Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada., L'Allier PL; Cardiovascular Genetics Centre and Research Centre, Montreal Heart Institute, Montreal, Quebec, Canada.; Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada., Garceau P; Cardiovascular Genetics Centre and Research Centre, Montreal Heart Institute, Montreal, Quebec, Canada.; Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada., Talajic M; Cardiovascular Genetics Centre and Research Centre, Montreal Heart Institute, Montreal, Quebec, Canada.; Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada., Gagliano Taliun SA; Cardiovascular Genetics Centre and Research Centre, Montreal Heart Institute, Montreal, Quebec, Canada.; Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada., Pinto YM; Department of Experimental Cardiology, Amsterdam Cardiovascular Sciences, University of Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands.; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart (ERN GUARD-HEART), Amsterdam, the Netherlands.; Department of Clinical Cardiology, Amsterdam Cardiovascular Sciences, University of Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands., Rakowski H; Division of Cardiology, Peter Munk Cardiac Centre, University Health Network, Toronto, Ontario, Canada., Pantazis A; Royal Brompton and Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK., Bai W; Department of Computing, Imperial College London, London, UK.; Department of Brain Sciences, Imperial College London, London, UK.; Data Science Institute, Imperial College London, London, UK., Baksi J; National Heart and Lung Institute, Imperial College London, London, UK.; Royal Brompton and Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK., Halliday BP; National Heart and Lung Institute, Imperial College London, London, UK.; Royal Brompton and Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK., Prasad SK; National Heart and Lung Institute, Imperial College London, London, UK.; Royal Brompton and Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK., Barton PJR; National Heart and Lung Institute, Imperial College London, London, UK.; MRC Laboratory of Medical Sciences, Imperial College London, London, UK.; Royal Brompton and Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK., O'Regan DP; MRC Laboratory of Medical Sciences, Imperial College London, London, UK., Cook SA; MRC Laboratory of Medical Sciences, Imperial College London, London, UK.; National Heart Centre, Singapore, Singapore.; Duke-National University of Singapore Medical School, Singapore, Singapore., de Boer RA; Department of Cardiology, Thorax Center, Cardiovascular Institute, Erasmus Medical Center, Rotterdam, the Netherlands., Christiaans I; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Michels M; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart (ERN GUARD-HEART), Amsterdam, the Netherlands.; Department of Cardiology, Thorax Center, Cardiovascular Institute, Erasmus Medical Center, Rotterdam, the Netherlands., Kramer CM; Department of Medicine, Cardiovascular Division, University of Virginia Health, Charlottesville, VA, USA., Ho CY; Cardiovascular Division, Brigham and Women's Hospital, Boston, MA, USA., Neubauer S; Radcliffe Department of Medicine, University of Oxford, Division of Cardiovascular Medicine, NIHR Oxford Biomedical Research Centre, Oxford, UK., Matthews PM; Department of Brain Sciences, Imperial College London, London, UK.; UK Dementia Research Institute, Imperial College London, London, UK., Wilde AAM; Department of Experimental Cardiology, Amsterdam Cardiovascular Sciences, University of Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands.; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart (ERN GUARD-HEART), Amsterdam, the Netherlands.; Department of Clinical Cardiology, Amsterdam Cardiovascular Sciences, University of Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands.; ECGen, Cardiogenetics Focus Group of EHRA, Biot, France., Tardif JC; Cardiovascular Genetics Centre and Research Centre, Montreal Heart Institute, Montreal, Quebec, Canada.; Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada., Olivotto I; Meyer Children's Hospital IRCCS, Florence, Italy., Adler A; Division of Cardiology, Peter Munk Cardiac Centre, University Health Network, Toronto, Ontario, Canada.; Department of Medicine, University of Toronto, Toronto, Ontario, Canada., Goel A; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK., Ware JS; National Heart and Lung Institute, Imperial College London, London, UK. j.ware@imperial.ac.uk.; MRC Laboratory of Medical Sciences, Imperial College London, London, UK. j.ware@imperial.ac.uk.; Royal Brompton and Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK. j.ware@imperial.ac.uk.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA. j.ware@imperial.ac.uk., Bezzina CR; Department of Experimental Cardiology, Amsterdam Cardiovascular Sciences, University of Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands. c.r.bezzina@amsterdamumc.nl.; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart (ERN GUARD-HEART), Amsterdam, the Netherlands. c.r.bezzina@amsterdamumc.nl., Watkins H; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK. hugh.watkins@rdm.ox.ac.uk.
Corporate Authors: Hypergenes InterOmics Collaborators, HCMR Investigators
Source: Nature genetics [Nat Genet] 2025 Mar; Vol. 57 (3), pp. 530-538. Date of Electronic Publication: 2025 Feb 18.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Large-scale genome-wide association analyses identify novel genetic loci and mechanisms in hypertrophic cardiomyopathy.
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Cardiovascular Genetics Centre and Research Centre, Montreal Heart Institute, Montreal, Quebec, Canada.; Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Francis+C%22">Francis C</searchLink>; National Heart and Lung Institute, Imperial College London, London, UK.; Royal Brompton and Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22West+DM%22">West DM</searchLink>; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Jurgens+SJ%22">Jurgens SJ</searchLink>; Department of Experimental Cardiology, Amsterdam Cardiovascular Sciences, University of Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands.; Cardiovascular Disease Initiative, Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Thomson+KL%22">Thomson KL</searchLink>; 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National Heart and Lung Institute, Imperial College London, London, UK.; MRC Laboratory of Medical Sciences, Imperial College London, London, UK.; Royal Brompton and Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22McGurk+KA%22">McGurk KA</searchLink>; National Heart and Lung Institute, Imperial College London, London, UK.; MRC Laboratory of Medical Sciences, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Mazzarotto+F%22">Mazzarotto F</searchLink>; National Heart and Lung Institute, Imperial College London, London, UK.; Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.<br /><searchLink fieldCode="AU" term="%22Boschi+B%22">Boschi B</searchLink>; Genetics Unit, Careggi University Hospital, Florence, Italy.<br /><searchLink fieldCode="AU" term="%22Pelo+E%22">Pelo E</searchLink>; Genetics Unit, Careggi University Hospital, Florence, Italy.<br /><searchLink fieldCode="AU" term="%22Lee+M%22">Lee M</searchLink>; 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Department of Experimental Cardiology, Amsterdam Cardiovascular Sciences, University of Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands.; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart (ERN GUARD-HEART), Amsterdam, the Netherlands.; Department of Clinical Cardiology, Amsterdam Cardiovascular Sciences, University of Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Slegtenhorst+MA%22">van Slegtenhorst MA</searchLink>; Department of Clinical Genetics, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Roslin+NM%22">Roslin NM</searchLink>; Program in Genetics and Genome Biology and The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Strug+LJ%22">Strug LJ</searchLink>; Program in Genetics and Genome Biology and The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, Ontario, Canada.; Departments of Statistical Sciences and Computer Science, University of Toronto, Toronto, Ontario, Canada.; Division of Biostatistics, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Salvi+E%22">Salvi E</searchLink>; Neuroalgology Unit, Fondazione IRCCS Istituto Neurologico 'Carlo Besta', Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Lanzani+C%22">Lanzani C</searchLink>; Genomics of Renal Diseases and Hypertension Unit and Nephrology Operative Unit, IRCCS San Raffaele Hospital, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22de+Marvao+A%22">de Marvao A</searchLink>; MRC Laboratory of Medical Sciences, Imperial College London, London, UK.; King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Roberts+JD%22">Roberts JD</searchLink>; Department of Medicine, Section of Cardiac Electrophysiology, Division of Cardiology, Western University, London, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Tremblay-Gravel+M%22">Tremblay-Gravel M</searchLink>; 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Cardiovascular Genetics Centre and Research Centre, Montreal Heart Institute, Montreal, Quebec, Canada.; Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Talajic+M%22">Talajic M</searchLink>; Cardiovascular Genetics Centre and Research Centre, Montreal Heart Institute, Montreal, Quebec, Canada.; Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Gagliano+Taliun+SA%22">Gagliano Taliun SA</searchLink>; Cardiovascular Genetics Centre and Research Centre, Montreal Heart Institute, Montreal, Quebec, Canada.; Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Pinto+YM%22">Pinto YM</searchLink>; Department of Experimental Cardiology, Amsterdam Cardiovascular Sciences, University of Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands.; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart (ERN GUARD-HEART), Amsterdam, the Netherlands.; Department of Clinical Cardiology, Amsterdam Cardiovascular Sciences, University of Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Rakowski+H%22">Rakowski H</searchLink>; Division of Cardiology, Peter Munk Cardiac Centre, University Health Network, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Pantazis+A%22">Pantazis A</searchLink>; Royal Brompton and Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Bai+W%22">Bai W</searchLink>; Department of Computing, Imperial College London, London, UK.; Department of Brain Sciences, Imperial College London, London, UK.; Data Science Institute, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Baksi+J%22">Baksi J</searchLink>; National Heart and Lung Institute, Imperial College London, London, UK.; Royal Brompton and Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Halliday+BP%22">Halliday BP</searchLink>; 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National Heart Centre, Singapore, Singapore.; Duke-National University of Singapore Medical School, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22de+Boer+RA%22">de Boer RA</searchLink>; Department of Cardiology, Thorax Center, Cardiovascular Institute, Erasmus Medical Center, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Christiaans+I%22">Christiaans I</searchLink>; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Michels+M%22">Michels M</searchLink>; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart (ERN GUARD-HEART), Amsterdam, the Netherlands.; Department of Cardiology, Thorax Center, Cardiovascular Institute, Erasmus Medical Center, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Kramer+CM%22">Kramer CM</searchLink>; Department of Medicine, Cardiovascular Division, University of Virginia Health, Charlottesville, VA, USA.<br /><searchLink fieldCode="AU" term="%22Ho+CY%22">Ho CY</searchLink>; Cardiovascular Division, Brigham and Women's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Neubauer+S%22">Neubauer S</searchLink>; Radcliffe Department of Medicine, University of Oxford, Division of Cardiovascular Medicine, NIHR Oxford Biomedical Research Centre, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Matthews+PM%22">Matthews PM</searchLink>; Department of Brain Sciences, Imperial College London, London, UK.; UK Dementia Research Institute, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Wilde+AAM%22">Wilde AAM</searchLink>; Department of Experimental Cardiology, Amsterdam Cardiovascular Sciences, University of Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands.; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart (ERN GUARD-HEART), Amsterdam, the Netherlands.; Department of Clinical Cardiology, Amsterdam Cardiovascular Sciences, University of Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands.; 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MRC Laboratory of Medical Sciences, Imperial College London, London, UK. j.ware@imperial.ac.uk.; Royal Brompton and Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK. j.ware@imperial.ac.uk.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA. j.ware@imperial.ac.uk.<br /><searchLink fieldCode="AU" term="%22Bezzina+CR%22">Bezzina CR</searchLink>; Department of Experimental Cardiology, Amsterdam Cardiovascular Sciences, University of Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands. c.r.bezzina@amsterdamumc.nl.; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart (ERN GUARD-HEART), Amsterdam, the Netherlands. c.r.bezzina@amsterdamumc.nl.<br /><searchLink fieldCode="AU" term="%22Watkins+H%22">Watkins H</searchLink>; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK. hugh.watkins@rdm.ox.ac.uk.
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      – TitleFull: Large-scale genome-wide association analyses identify novel genetic loci and mechanisms in hypertrophic cardiomyopathy.
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            – D: 01
              M: 03
              Text: 2025 Mar
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 1546-1718
          Numbering:
            – Type: volume
              Value: 57
            – Type: issue
              Value: 3
          Titles:
            – TitleFull: Nature genetics
              Type: main
ResultId 1