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Targeting cIAP2 in a novel senolytic strategy prevents glioblastoma recurrence after radiotherapy.

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Title: Targeting cIAP2 in a novel senolytic strategy prevents glioblastoma recurrence after radiotherapy.
Authors: Tomimatsu N; Department of Neurosurgery, University of Texas Health, San Antonio, TX, USA., Di Cristofaro LFM; Department of Neurosurgery, University of Texas Health, San Antonio, TX, USA., Kanji S; Department of Neurosurgery, University of Texas Health, San Antonio, TX, USA., Samentar L; Department of Neurosurgery, University of Texas Health, San Antonio, TX, USA., Jordan BR; Department of Neurosurgery, University of Texas Health, San Antonio, TX, USA.; Department of Biochemistry and Structural Biology, University of Texas Health, San Antonio, TX, USA., Kittler R; Eugene McDermott Center for Human Growth and Development, University of Texas Southwestern Medical Center, Dallas, TX, USA., Habib AA; Department of Neurology, University of Texas Southwestern Medical Center, Dallas, TX, USA., Espindola-Netto JM; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA., Tchkonia T; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA., Kirkland JL; Department of Medicine, Mayo Clinic, Rochester, MN, USA., Burns TC; Department of Neurological Surgery, Mayo Clinic, Rochester, MN, USA., Sarkaria JN; Department of Radiation Oncology, Mayo Clinic, Rochester, MN, USA., Gilbert A; Department of Pathology, University of Texas Health, San Antonio, TX, USA., Floyd JR; Department of Neurosurgery, University of Texas Health, San Antonio, TX, USA., Hromas R; Department of Medicine, University of Texas Health, San Antonio, TX, USA., Zhao W; Department of Biochemistry and Structural Biology, University of Texas Health, San Antonio, TX, USA., Zhou D; Department of Biochemistry and Structural Biology, University of Texas Health, San Antonio, TX, USA., Sung P; Department of Biochemistry and Structural Biology, University of Texas Health, San Antonio, TX, USA., Mukherjee B; Department of Neurosurgery, University of Texas Health, San Antonio, TX, USA. mukherjeeb@uthscsa.edu., Burma S; Department of Neurosurgery, University of Texas Health, San Antonio, TX, USA. burma@uthscsa.edu.; Department of Biochemistry and Structural Biology, University of Texas Health, San Antonio, TX, USA. burma@uthscsa.edu.
Source: EMBO molecular medicine [EMBO Mol Med] 2025 Apr; Vol. 17 (4), pp. 645-678. Date of Electronic Publication: 2025 Feb 19.
Publication Type: Journal Article
Journal Info: Publisher: EMBO Press Country of Publication: Germany NLM ID: 101487380 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1757-4684 (Electronic) Linking ISSN: 17574676 NLM ISO Abbreviation: EMBO Mol Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Targeting cIAP2 in a novel senolytic strategy prevents glioblastoma recurrence after radiotherapy.
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  Data: <searchLink fieldCode="AU" term="%22Tomimatsu+N%22">Tomimatsu N</searchLink>; Department of Neurosurgery, University of Texas Health, San Antonio, TX, USA.<br /><searchLink fieldCode="AU" term="%22Di+Cristofaro+LFM%22">Di Cristofaro LFM</searchLink>; Department of Neurosurgery, University of Texas Health, San Antonio, TX, USA.<br /><searchLink fieldCode="AU" term="%22Kanji+S%22">Kanji S</searchLink>; Department of Neurosurgery, University of Texas Health, San Antonio, TX, USA.<br /><searchLink fieldCode="AU" term="%22Samentar+L%22">Samentar L</searchLink>; Department of Neurosurgery, University of Texas Health, San Antonio, TX, USA.<br /><searchLink fieldCode="AU" term="%22Jordan+BR%22">Jordan BR</searchLink>; Department of Neurosurgery, University of Texas Health, San Antonio, TX, USA.; Department of Biochemistry and Structural Biology, University of Texas Health, San Antonio, TX, USA.<br /><searchLink fieldCode="AU" term="%22Kittler+R%22">Kittler R</searchLink>; Eugene McDermott Center for Human Growth and Development, University of Texas Southwestern Medical Center, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Habib+AA%22">Habib AA</searchLink>; Department of Neurology, University of Texas Southwestern Medical Center, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Espindola-Netto+JM%22">Espindola-Netto JM</searchLink>; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Tchkonia+T%22">Tchkonia T</searchLink>; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Kirkland+JL%22">Kirkland JL</searchLink>; Department of Medicine, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Burns+TC%22">Burns TC</searchLink>; Department of Neurological Surgery, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Sarkaria+JN%22">Sarkaria JN</searchLink>; Department of Radiation Oncology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Gilbert+A%22">Gilbert A</searchLink>; Department of Pathology, University of Texas Health, San Antonio, TX, USA.<br /><searchLink fieldCode="AU" term="%22Floyd+JR%22">Floyd JR</searchLink>; Department of Neurosurgery, University of Texas Health, San Antonio, TX, USA.<br /><searchLink fieldCode="AU" term="%22Hromas+R%22">Hromas R</searchLink>; Department of Medicine, University of Texas Health, San Antonio, TX, USA.<br /><searchLink fieldCode="AU" term="%22Zhao+W%22">Zhao W</searchLink>; Department of Biochemistry and Structural Biology, University of Texas Health, San Antonio, TX, USA.<br /><searchLink fieldCode="AU" term="%22Zhou+D%22">Zhou D</searchLink>; Department of Biochemistry and Structural Biology, University of Texas Health, San Antonio, TX, USA.<br /><searchLink fieldCode="AU" term="%22Sung+P%22">Sung P</searchLink>; Department of Biochemistry and Structural Biology, University of Texas Health, San Antonio, TX, USA.<br /><searchLink fieldCode="AU" term="%22Mukherjee+B%22">Mukherjee B</searchLink>; Department of Neurosurgery, University of Texas Health, San Antonio, TX, USA. mukherjeeb@uthscsa.edu.<br /><searchLink fieldCode="AU" term="%22Burma+S%22">Burma S</searchLink>; Department of Neurosurgery, University of Texas Health, San Antonio, TX, USA. burma@uthscsa.edu.; Department of Biochemistry and Structural Biology, University of Texas Health, San Antonio, TX, USA. burma@uthscsa.edu.
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  Data: <searchLink fieldCode="JN" term="%22101487380%22">EMBO molecular medicine</searchLink> [EMBO Mol Med] 2025 Apr; Vol. 17 (4), pp. 645-678. <i>Date of Electronic Publication: </i>2025 Feb 19.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22EMBO+Press%22">EMBO Press </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>101487380 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1757-4684 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217574676%22">17574676 </searchLink><i>NLM ISO Abbreviation: </i>EMBO Mol Med <i>Subsets: </i>MEDLINE
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