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RTN3 regulates collagen biosynthesis and profibrotic macrophage differentiation to promote pulmonary fibrosis via interacting with CRTH2.

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Title: RTN3 regulates collagen biosynthesis and profibrotic macrophage differentiation to promote pulmonary fibrosis via interacting with CRTH2.
Authors: Wang CY; Department of Respiratory and Critical Care Medicine, Research Unit of Respiratory Disease of Central South University, Clinical Medical Research Center for Respiratory and Critical Care Medicine in Hunan Province, Diagnosis and Treatment Center of Respiratory Disease, The Second Xiangya Hospital, Central South University, Changsha, China.; Department of Cell Biology, Hunan Key Laboratory of Medical Genetics, Hunan Key Laboratory of Animal Models for Human Disease, School of Life Sciences, Central South University, Changsha, China.; Institute for Advance Study, Central South University, Changsha, China., Chen YQ; Department of Cell Biology, Hunan Key Laboratory of Medical Genetics, Hunan Key Laboratory of Animal Models for Human Disease, School of Life Sciences, Central South University, Changsha, China.; Department of Cardiology, The Second Xiangya Hospital, Central South University, Changsha, China., Huang H; Department of Cell Biology, Hunan Key Laboratory of Medical Genetics, Hunan Key Laboratory of Animal Models for Human Disease, School of Life Sciences, Central South University, Changsha, China., Yuan ZZ; Department of Cell Biology, Hunan Key Laboratory of Medical Genetics, Hunan Key Laboratory of Animal Models for Human Disease, School of Life Sciences, Central South University, Changsha, China., Dong Y; Department of Cell Biology, Hunan Key Laboratory of Medical Genetics, Hunan Key Laboratory of Animal Models for Human Disease, School of Life Sciences, Central South University, Changsha, China., Jin JY; Department of Cell Biology, Hunan Key Laboratory of Medical Genetics, Hunan Key Laboratory of Animal Models for Human Disease, School of Life Sciences, Central South University, Changsha, China., Long JY; Department of Cell Biology, Hunan Key Laboratory of Medical Genetics, Hunan Key Laboratory of Animal Models for Human Disease, School of Life Sciences, Central South University, Changsha, China., Liu L; Department of Respiratory and Critical Care Medicine, Research Unit of Respiratory Disease of Central South University, Clinical Medical Research Center for Respiratory and Critical Care Medicine in Hunan Province, Diagnosis and Treatment Center of Respiratory Disease, The Second Xiangya Hospital, Central South University, Changsha, China. docliulv@csu.edu.cn., Fan LL; Department of Respiratory and Critical Care Medicine, Research Unit of Respiratory Disease of Central South University, Clinical Medical Research Center for Respiratory and Critical Care Medicine in Hunan Province, Diagnosis and Treatment Center of Respiratory Disease, The Second Xiangya Hospital, Central South University, Changsha, China. swfanliangliang@csu.edu.cn.; Department of Cell Biology, Hunan Key Laboratory of Medical Genetics, Hunan Key Laboratory of Animal Models for Human Disease, School of Life Sciences, Central South University, Changsha, China. swfanliangliang@csu.edu.cn., Xiang R; Department of Respiratory and Critical Care Medicine, Research Unit of Respiratory Disease of Central South University, Clinical Medical Research Center for Respiratory and Critical Care Medicine in Hunan Province, Diagnosis and Treatment Center of Respiratory Disease, The Second Xiangya Hospital, Central South University, Changsha, China. shirlesmile@csu.edu.cn.; Department of Cell Biology, Hunan Key Laboratory of Medical Genetics, Hunan Key Laboratory of Animal Models for Human Disease, School of Life Sciences, Central South University, Changsha, China. shirlesmile@csu.edu.cn.
Source: Molecular medicine (Cambridge, Mass.) [Mol Med] 2025 Feb 19; Vol. 31 (1), pp. 63. Date of Electronic Publication: 2025 Feb 19.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 9501023 Publication Model: Electronic Cited Medium: Internet ISSN: 1528-3658 (Electronic) Linking ISSN: 10761551 NLM ISO Abbreviation: Mol Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: RTN3 regulates collagen biosynthesis and profibrotic macrophage differentiation to promote pulmonary fibrosis via interacting with CRTH2.
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  Data: <searchLink fieldCode="AU" term="%22Wang+CY%22">Wang CY</searchLink>; Department of Respiratory and Critical Care Medicine, Research Unit of Respiratory Disease of Central South University, Clinical Medical Research Center for Respiratory and Critical Care Medicine in Hunan Province, Diagnosis and Treatment Center of Respiratory Disease, The Second Xiangya Hospital, Central South University, Changsha, China.; Department of Cell Biology, Hunan Key Laboratory of Medical Genetics, Hunan Key Laboratory of Animal Models for Human Disease, School of Life Sciences, Central South University, Changsha, China.; Institute for Advance Study, Central South University, Changsha, China.<br /><searchLink fieldCode="AU" term="%22Chen+YQ%22">Chen YQ</searchLink>; Department of Cell Biology, Hunan Key Laboratory of Medical Genetics, Hunan Key Laboratory of Animal Models for Human Disease, School of Life Sciences, Central South University, Changsha, China.; Department of Cardiology, The Second Xiangya Hospital, Central South University, Changsha, China.<br /><searchLink fieldCode="AU" term="%22Huang+H%22">Huang H</searchLink>; Department of Cell Biology, Hunan Key Laboratory of Medical Genetics, Hunan Key Laboratory of Animal Models for Human Disease, School of Life Sciences, Central South University, Changsha, China.<br /><searchLink fieldCode="AU" term="%22Yuan+ZZ%22">Yuan ZZ</searchLink>; Department of Cell Biology, Hunan Key Laboratory of Medical Genetics, Hunan Key Laboratory of Animal Models for Human Disease, School of Life Sciences, Central South University, Changsha, China.<br /><searchLink fieldCode="AU" term="%22Dong+Y%22">Dong Y</searchLink>; Department of Cell Biology, Hunan Key Laboratory of Medical Genetics, Hunan Key Laboratory of Animal Models for Human Disease, School of Life Sciences, Central South University, Changsha, China.<br /><searchLink fieldCode="AU" term="%22Jin+JY%22">Jin JY</searchLink>; Department of Cell Biology, Hunan Key Laboratory of Medical Genetics, Hunan Key Laboratory of Animal Models for Human Disease, School of Life Sciences, Central South University, Changsha, China.<br /><searchLink fieldCode="AU" term="%22Long+JY%22">Long JY</searchLink>; Department of Cell Biology, Hunan Key Laboratory of Medical Genetics, Hunan Key Laboratory of Animal Models for Human Disease, School of Life Sciences, Central South University, Changsha, China.<br /><searchLink fieldCode="AU" term="%22Liu+L%22">Liu L</searchLink>; Department of Respiratory and Critical Care Medicine, Research Unit of Respiratory Disease of Central South University, Clinical Medical Research Center for Respiratory and Critical Care Medicine in Hunan Province, Diagnosis and Treatment Center of Respiratory Disease, The Second Xiangya Hospital, Central South University, Changsha, China. docliulv@csu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Fan+LL%22">Fan LL</searchLink>; Department of Respiratory and Critical Care Medicine, Research Unit of Respiratory Disease of Central South University, Clinical Medical Research Center for Respiratory and Critical Care Medicine in Hunan Province, Diagnosis and Treatment Center of Respiratory Disease, The Second Xiangya Hospital, Central South University, Changsha, China. swfanliangliang@csu.edu.cn.; Department of Cell Biology, Hunan Key Laboratory of Medical Genetics, Hunan Key Laboratory of Animal Models for Human Disease, School of Life Sciences, Central South University, Changsha, China. swfanliangliang@csu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Xiang+R%22">Xiang R</searchLink>; Department of Respiratory and Critical Care Medicine, Research Unit of Respiratory Disease of Central South University, Clinical Medical Research Center for Respiratory and Critical Care Medicine in Hunan Province, Diagnosis and Treatment Center of Respiratory Disease, The Second Xiangya Hospital, Central South University, Changsha, China. shirlesmile@csu.edu.cn.; Department of Cell Biology, Hunan Key Laboratory of Medical Genetics, Hunan Key Laboratory of Animal Models for Human Disease, School of Life Sciences, Central South University, Changsha, China. shirlesmile@csu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%229501023%22">Molecular medicine (Cambridge, Mass.)</searchLink> [Mol Med] 2025 Feb 19; Vol. 31 (1), pp. 63. <i>Date of Electronic Publication: </i>2025 Feb 19.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9501023 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1528-3658 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210761551%22">10761551 </searchLink><i>NLM ISO Abbreviation: </i>Mol Med <i>Subsets: </i>MEDLINE
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        Value: 10.1186/s10020-025-01119-3
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        Text: English
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        StartPage: 63
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      – TitleFull: RTN3 regulates collagen biosynthesis and profibrotic macrophage differentiation to promote pulmonary fibrosis via interacting with CRTH2.
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              Text: 2025 Feb 19
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