Remdesivir is active in vitro against tick-borne encephalitis virus and selects for resistance mutations in the viral RNA-dependent RNA polymerase.

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Title: Remdesivir is active in vitro against tick-borne encephalitis virus and selects for resistance mutations in the viral RNA-dependent RNA polymerase.
Authors: Nyström K; Department of Infectious Diseases/Virology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Department of Clinical Microbiology, Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden., Trybala E; Department of Infectious Diseases/Virology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Said J; Department of Infectious Diseases/Virology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Department of Clinical Microbiology, Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden., Roth A; Department of Infectious Diseases/Virology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Department of Clinical Microbiology, Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden., Patzi Churqui M; Department of Infectious Diseases/Virology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Kärmander A; Department of Infectious Diseases/Virology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Cihlar T; Gilead Sciences, Foster City, CA, USA., Bilello JP; Gilead Sciences, Foster City, CA, USA., Bergström T; Department of Infectious Diseases/Virology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Lagging M; Department of Infectious Diseases/Virology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Department of Clinical Microbiology, Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden.
Source: Infectious diseases (London, England) [Infect Dis (Lond)] 2025 Jul; Vol. 57 (7), pp. 628-635. Date of Electronic Publication: 2025 Feb 20.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 101650235 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2374-4243 (Electronic) Linking ISSN: 23744243 NLM ISO Abbreviation: Infect Dis (Lond) Subsets: MEDLINE
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  Data: Remdesivir is active in vitro against tick-borne encephalitis virus and selects for resistance mutations in the viral RNA-dependent RNA polymerase.
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  Data: <searchLink fieldCode="AU" term="%22Nyström+K%22">Nyström K</searchLink>; Department of Infectious Diseases/Virology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Department of Clinical Microbiology, Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Trybala+E%22">Trybala E</searchLink>; Department of Infectious Diseases/Virology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Said+J%22">Said J</searchLink>; Department of Infectious Diseases/Virology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Department of Clinical Microbiology, Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Roth+A%22">Roth A</searchLink>; Department of Infectious Diseases/Virology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Department of Clinical Microbiology, Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Patzi+Churqui+M%22">Patzi Churqui M</searchLink>; Department of Infectious Diseases/Virology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Kärmander+A%22">Kärmander A</searchLink>; Department of Infectious Diseases/Virology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Cihlar+T%22">Cihlar T</searchLink>; Gilead Sciences, Foster City, CA, USA.<br /><searchLink fieldCode="AU" term="%22Bilello+JP%22">Bilello JP</searchLink>; Gilead Sciences, Foster City, CA, USA.<br /><searchLink fieldCode="AU" term="%22Bergström+T%22">Bergström T</searchLink>; Department of Infectious Diseases/Virology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Lagging+M%22">Lagging M</searchLink>; Department of Infectious Diseases/Virology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Department of Clinical Microbiology, Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden.
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  Data: <searchLink fieldCode="JN" term="%22101650235%22">Infectious diseases (London, England)</searchLink> [Infect Dis (Lond)] 2025 Jul; Vol. 57 (7), pp. 628-635. <i>Date of Electronic Publication: </i>2025 Feb 20.
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  Data: Journal Article; Research Support, Non-U.S. Gov't
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Informa+Healthcare%22">Informa Healthcare </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101650235 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2374-4243 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2223744243%22">23744243 </searchLink><i>NLM ISO Abbreviation: </i>Infect Dis (Lond) <i>Subsets: </i>MEDLINE
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        Value: 10.1080/23744235.2025.2468510
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              Text: 2025 Jul
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