2024 update of the AGIHO guideline on diagnosis and empirical treatment of fever of unknown origin (FUO) in adult neutropenic patients with solid tumours and hematological malignancies.

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Title: 2024 update of the AGIHO guideline on diagnosis and empirical treatment of fever of unknown origin (FUO) in adult neutropenic patients with solid tumours and hematological malignancies.
Authors: Sandherr M; Specialist Clinic for Hematology and Oncology, Medical Care Center Penzberg, Germany., Stemler J; University of Cologne, Institute of Translational Research, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Cologne, Germany.; University of Cologne, Faculty of Medicine, and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD) and Excellence Center for Medical Mycology (ECMM), Cologne, Germany.; German Centre for Infection Research (DZIF), Partner Site Bonn-Cologne Department, Cologne, Germany., Schalk E; Department of Hematology, Oncology and Cell Therapy, Medical Faculty, Otto von Guericke University Magdeburg, Magdeburg, Germany., Hattenhauer T; Department of Oncology, Hematology, Rheumatology and Immune-Oncology, University Hospital Bonn, Bonn, Germany., Hentrich M; Department of Hematology and Oncology, Red Cross Hospital Munich, Ludwig Maximilian University Munich, Munich, Germany., Hertenstein B; Department of Medicine, Clinic I - Hematology, Oncology, Infectiology, Department of Intensive Care and Emergency Medicine, Klinikum Bremen-Mitte, Bremen, Germany., Hohmann C; Department of Medicine, Clinic I - Hematology, Oncology, Infectiology, Department of Intensive Care and Emergency Medicine, Klinikum Bremen-Mitte, Bremen, Germany., Mellinghoff SC; University of Cologne, Institute of Translational Research, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Cologne, Germany.; University of Cologne, Faculty of Medicine, and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD) and Excellence Center for Medical Mycology (ECMM), Cologne, Germany.; German Centre for Infection Research (DZIF), Partner Site Bonn-Cologne Department, Cologne, Germany., Mispelbaum R; Department of Oncology, Hematology, Rheumatology and Immune-Oncology, University Hospital Bonn, Bonn, Germany., Rieger C; Department of Hematology and Oncology Germering, Germering, Germany., Schmidt-Hieber M; Clinic for Oncology, Hematology, Pneumology, Nephrology and Diabetology, Carl-Thiem Clinic, Cottbus, Germany., Sprute R; University of Cologne, Faculty of Medicine, and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD) and Excellence Center for Medical Mycology (ECMM), Cologne, Germany., Weiss G; Department of Internal Medicine II, Infectious Diseases, Immunology, Rheumatology, Pneumology, Medical University of Innsbruck, Innsbruck, Austria., Cornely OA; University of Cologne, Institute of Translational Research, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Cologne, Germany.; University of Cologne, Faculty of Medicine, and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD) and Excellence Center for Medical Mycology (ECMM), Cologne, Germany.; German Centre for Infection Research (DZIF), Partner Site Bonn-Cologne Department, Cologne, Germany., Henze L; Department of Medicine, Clinic III - Hematology, Oncology, Palliative Medicine, Rostock University Medical Center, Rostock, Germany.; Department of Internal Medicine II, Hematology, Oncology and Palliative Medicine, Asklepios Hospital Harz, Goslar, Germany., Lass-Floerl C; Institut of Hygiene and Medical Microbiology, Medical University of Innsbruck, Innsbruck, Austria., Beutel G; Department of Internal Medicine, Hematology, Oncology and Stem Cell Transplantation, Medical University of Hannover, Hannover, Germany., Classen AY; University of Cologne, Faculty of Medicine, and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD) and Excellence Center for Medical Mycology (ECMM), Cologne, Germany.; German Centre for Infection Research (DZIF), Partner Site Bonn-Cologne, Cologne, Germany., Freise NF; Department of Gastroenterology, Hepatology and Infectious Diseases, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf, Germany.; Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD), Germany., Karthaus M; Department Hematology, Oncology and Palliative Care, Klinikum Neuperlach and Harlaching, Munich, Germany., Koehler P; University of Cologne, Institute of Translational Research, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Cologne, Germany., Krause R; Division of Infectious Diseases, Department of Internal Medicine, Medical University of Graz, Austria.; BioTechMed, Graz, Austria., Neuhann J; University of Cologne, Faculty of Medicine, and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD) and Excellence Center for Medical Mycology (ECMM), Cologne, Germany., Orth HM; Department of Gastroenterology, Hepatology and Infectious Diseases, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf, Germany.; Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD), Germany., Penack O; Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Hematology, Oncology and Tumorimmunology, Berlin, Germany., Schaich M; Department of Hematology, Oncology and Palliative Care, Rems-Murr-Klinikum Winnenden, Germany., Spiekermann K; Department of Medicine III, LMU University Hospital, LMU Munich, Germany., Voigt S; Institute for Virology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany., Weissinger F; Evangelic Hospital Bethel, Bielefeld, Germany., Busch E; Internal Medicine V, Hematology, Oncology and Rheumatology, Heidelberg University Hospital, Heidelberg, Germany.
Source: The Lancet regional health. Europe [Lancet Reg Health Eur] 2025 Jan 31; Vol. 51, pp. 101214. Date of Electronic Publication: 2025 Jan 31 (Print Publication: 2025).
Publication Type: Journal Article; Review
Journal Info: Publisher: [Oxford] Country of Publication: England NLM ID: 101777707 Publication Model: eCollection Cited Medium: Internet ISSN: 2666-7762 (Electronic) Linking ISSN: 26667762 NLM ISO Abbreviation: Lancet Reg Health Eur Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: 2024 update of the AGIHO guideline on diagnosis and empirical treatment of fever of unknown origin (FUO) in adult neutropenic patients with solid tumours and hematological malignancies.
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  Label: Authors
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  Data: <searchLink fieldCode="AU" term="%22Sandherr+M%22">Sandherr M</searchLink>; Specialist Clinic for Hematology and Oncology, Medical Care Center Penzberg, Germany.<br /><searchLink fieldCode="AU" term="%22Stemler+J%22">Stemler J</searchLink>; University of Cologne, Institute of Translational Research, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Cologne, Germany.; University of Cologne, Faculty of Medicine, and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD) and Excellence Center for Medical Mycology (ECMM), Cologne, Germany.; German Centre for Infection Research (DZIF), Partner Site Bonn-Cologne Department, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Schalk+E%22">Schalk E</searchLink>; Department of Hematology, Oncology and Cell Therapy, Medical Faculty, Otto von Guericke University Magdeburg, Magdeburg, Germany.<br /><searchLink fieldCode="AU" term="%22Hattenhauer+T%22">Hattenhauer T</searchLink>; Department of Oncology, Hematology, Rheumatology and Immune-Oncology, University Hospital Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Hentrich+M%22">Hentrich M</searchLink>; Department of Hematology and Oncology, Red Cross Hospital Munich, Ludwig Maximilian University Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Hertenstein+B%22">Hertenstein B</searchLink>; Department of Medicine, Clinic I - Hematology, Oncology, Infectiology, Department of Intensive Care and Emergency Medicine, Klinikum Bremen-Mitte, Bremen, Germany.<br /><searchLink fieldCode="AU" term="%22Hohmann+C%22">Hohmann C</searchLink>; Department of Medicine, Clinic I - Hematology, Oncology, Infectiology, Department of Intensive Care and Emergency Medicine, Klinikum Bremen-Mitte, Bremen, Germany.<br /><searchLink fieldCode="AU" term="%22Mellinghoff+SC%22">Mellinghoff SC</searchLink>; University of Cologne, Institute of Translational Research, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Cologne, Germany.; University of Cologne, Faculty of Medicine, and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD) and Excellence Center for Medical Mycology (ECMM), Cologne, Germany.; German Centre for Infection Research (DZIF), Partner Site Bonn-Cologne Department, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Mispelbaum+R%22">Mispelbaum R</searchLink>; Department of Oncology, Hematology, Rheumatology and Immune-Oncology, University Hospital Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Rieger+C%22">Rieger C</searchLink>; Department of Hematology and Oncology Germering, Germering, Germany.<br /><searchLink fieldCode="AU" term="%22Schmidt-Hieber+M%22">Schmidt-Hieber M</searchLink>; Clinic for Oncology, Hematology, Pneumology, Nephrology and Diabetology, Carl-Thiem Clinic, Cottbus, Germany.<br /><searchLink fieldCode="AU" term="%22Sprute+R%22">Sprute R</searchLink>; University of Cologne, Faculty of Medicine, and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD) and Excellence Center for Medical Mycology (ECMM), Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Weiss+G%22">Weiss G</searchLink>; Department of Internal Medicine II, Infectious Diseases, Immunology, Rheumatology, Pneumology, Medical University of Innsbruck, Innsbruck, Austria.<br /><searchLink fieldCode="AU" term="%22Cornely+OA%22">Cornely OA</searchLink>; University of Cologne, Institute of Translational Research, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Cologne, Germany.; University of Cologne, Faculty of Medicine, and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD) and Excellence Center for Medical Mycology (ECMM), Cologne, Germany.; German Centre for Infection Research (DZIF), Partner Site Bonn-Cologne Department, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Henze+L%22">Henze L</searchLink>; Department of Medicine, Clinic III - Hematology, Oncology, Palliative Medicine, Rostock University Medical Center, Rostock, Germany.; Department of Internal Medicine II, Hematology, Oncology and Palliative Medicine, Asklepios Hospital Harz, Goslar, Germany.<br /><searchLink fieldCode="AU" term="%22Lass-Floerl+C%22">Lass-Floerl C</searchLink>; Institut of Hygiene and Medical Microbiology, Medical University of Innsbruck, Innsbruck, Austria.<br /><searchLink fieldCode="AU" term="%22Beutel+G%22">Beutel G</searchLink>; Department of Internal Medicine, Hematology, Oncology and Stem Cell Transplantation, Medical University of Hannover, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Classen+AY%22">Classen AY</searchLink>; University of Cologne, Faculty of Medicine, and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD) and Excellence Center for Medical Mycology (ECMM), Cologne, Germany.; German Centre for Infection Research (DZIF), Partner Site Bonn-Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Freise+NF%22">Freise NF</searchLink>; Department of Gastroenterology, Hepatology and Infectious Diseases, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf, Germany.; Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD), Germany.<br /><searchLink fieldCode="AU" term="%22Karthaus+M%22">Karthaus M</searchLink>; Department Hematology, Oncology and Palliative Care, Klinikum Neuperlach and Harlaching, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Koehler+P%22">Koehler P</searchLink>; University of Cologne, Institute of Translational Research, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Krause+R%22">Krause R</searchLink>; Division of Infectious Diseases, Department of Internal Medicine, Medical University of Graz, Austria.; BioTechMed, Graz, Austria.<br /><searchLink fieldCode="AU" term="%22Neuhann+J%22">Neuhann J</searchLink>; University of Cologne, Faculty of Medicine, and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD) and Excellence Center for Medical Mycology (ECMM), Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Orth+HM%22">Orth HM</searchLink>; Department of Gastroenterology, Hepatology and Infectious Diseases, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf, Germany.; Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD), Germany.<br /><searchLink fieldCode="AU" term="%22Penack+O%22">Penack O</searchLink>; Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Hematology, Oncology and Tumorimmunology, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Schaich+M%22">Schaich M</searchLink>; Department of Hematology, Oncology and Palliative Care, Rems-Murr-Klinikum Winnenden, Germany.<br /><searchLink fieldCode="AU" term="%22Spiekermann+K%22">Spiekermann K</searchLink>; Department of Medicine III, LMU University Hospital, LMU Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Voigt+S%22">Voigt S</searchLink>; Institute for Virology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Weissinger+F%22">Weissinger F</searchLink>; Evangelic Hospital Bethel, Bielefeld, Germany.<br /><searchLink fieldCode="AU" term="%22Busch+E%22">Busch E</searchLink>; Internal Medicine V, Hematology, Oncology and Rheumatology, Heidelberg University Hospital, Heidelberg, Germany.
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  Data: <searchLink fieldCode="JN" term="%22101777707%22">The Lancet regional health. Europe</searchLink> [Lancet Reg Health Eur] 2025 Jan 31; Vol. 51, pp. 101214. <i>Date of Electronic Publication: </i>2025 Jan 31 (<i>Print Publication: </i>2025).
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