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Receptor Allostery Promotes Context-Dependent Sonic Hedgehog Signaling During Embryonic Development.

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Title: Receptor Allostery Promotes Context-Dependent Sonic Hedgehog Signaling During Embryonic Development.
Authors: Ansari SS; Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Dillard ME; Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Ghonim M; Department of Host Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Zhang Y; Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Stewart DP; Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Canac R; Department of Pediatrics, The University of Chicago, Chicago, IL 60637, USA., Moskowitz IP; Department of Pediatrics, The University of Chicago, Chicago, IL 60637, USA., Wright WC; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Daly CA; Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Pruett-Miller SM; Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.; Center for Advanced Genome Engineering, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Steinberg J; Center for In Vivo Imaging and Therapy, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Wang YD; Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Chen T; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Thomas PG; Department of Host Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Bridges JP; Department of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, National Jewish Health, Denver, CO, 80206, USA.; Department of Medicine, Division of Pulmonary Sciences and Critical Care, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045., Ogden SK; Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Jan 29. Date of Electronic Publication: 2025 Jan 29.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Receptor Allostery Promotes Context-Dependent Sonic Hedgehog Signaling During Embryonic Development.
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  Data: <searchLink fieldCode="AU" term="%22Ansari+SS%22">Ansari SS</searchLink>; Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.<br /><searchLink fieldCode="AU" term="%22Dillard+ME%22">Dillard ME</searchLink>; Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.<br /><searchLink fieldCode="AU" term="%22Ghonim+M%22">Ghonim M</searchLink>; Department of Host Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.<br /><searchLink fieldCode="AU" term="%22Stewart+DP%22">Stewart DP</searchLink>; Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.<br /><searchLink fieldCode="AU" term="%22Canac+R%22">Canac R</searchLink>; Department of Pediatrics, The University of Chicago, Chicago, IL 60637, USA.<br /><searchLink fieldCode="AU" term="%22Moskowitz+IP%22">Moskowitz IP</searchLink>; Department of Pediatrics, The University of Chicago, Chicago, IL 60637, USA.<br /><searchLink fieldCode="AU" term="%22Wright+WC%22">Wright WC</searchLink>; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.<br /><searchLink fieldCode="AU" term="%22Daly+CA%22">Daly CA</searchLink>; Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.<br /><searchLink fieldCode="AU" term="%22Pruett-Miller+SM%22">Pruett-Miller SM</searchLink>; Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.; Center for Advanced Genome Engineering, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.<br /><searchLink fieldCode="AU" term="%22Steinberg+J%22">Steinberg J</searchLink>; Center for In Vivo Imaging and Therapy, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.<br /><searchLink fieldCode="AU" term="%22Wang+YD%22">Wang YD</searchLink>; Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.<br /><searchLink fieldCode="AU" term="%22Chen+T%22">Chen T</searchLink>; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.<br /><searchLink fieldCode="AU" term="%22Thomas+PG%22">Thomas PG</searchLink>; Department of Host Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.<br /><searchLink fieldCode="AU" term="%22Bridges+JP%22">Bridges JP</searchLink>; Department of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, National Jewish Health, Denver, CO, 80206, USA.; Department of Medicine, Division of Pulmonary Sciences and Critical Care, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045.<br /><searchLink fieldCode="AU" term="%22Ogden+SK%22">Ogden SK</searchLink>; Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
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