AI-assisted protein design to rapidly convert antibody sequences to intrabodies targeting diverse peptides and histone modifications.
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| Title: | AI-assisted protein design to rapidly convert antibody sequences to intrabodies targeting diverse peptides and histone modifications. |
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| Authors: | Galindo G; Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO, USA., Maejima D; School of Life Science and Technology, Institute of Science Tokyo, Yokohama, Japan., DeRoo J; School of Biomedical Engineering, Colorado State University, Fort Collins, CO, USA., Burlingham SR; Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO, USA., Fixen G; Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO, USA., Morisaki T; Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO, USA., Febvre HP; Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO, USA., Hasbrook R; Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO, USA., Zhao N; Department of Biochemistry and Molecular Genetics, University of Colorado-Anschutz Medical Campus, Aurora, CO, USA., Ghosh S; School of Biomedical Engineering, Colorado State University, Fort Collins, CO, USA.; Department of Mechanical Engineering, Colorado State University, Fort Collins, CO, USA., Mayton EH; Department of Microbiology, Immunology, & Pathology, Colorado State University, Fort Collins, CO, USA., Snow CD; Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO, USA.; School of Biomedical Engineering, Colorado State University, Fort Collins, CO, USA.; Department of Chemical & Biological Engineering, Colorado State University, Fort Collins, CO, USA., Geiss BJ; School of Biomedical Engineering, Colorado State University, Fort Collins, CO, USA.; Department of Microbiology, Immunology, & Pathology, Colorado State University, Fort Collins, CO, USA., Ohkawa Y; Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan., Sato Y; Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.; Cell Biology Center, Institute of Innovative Research, Tokyo Institute of Technology, Yokohama, Japan., Kimura H; School of Life Science and Technology, Institute of Science Tokyo, Yokohama, Japan.; Cell Biology Center, Institute of Innovative Research, Tokyo Institute of Technology, Yokohama, Japan.; Cell Biology Center, Institute of Integrated Research, Institute of Science Tokyo, Yokohama, Japan., Stasevich TJ; Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO, USA.; School of Biomedical Engineering, Colorado State University, Fort Collins, CO, USA.; Department of Chemical & Biological Engineering, Colorado State University, Fort Collins, CO, USA.; Cell Biology Center, Institute of Integrated Research, Institute of Science Tokyo, Yokohama, Japan. |
| Source: | BioRxiv : the preprint server for biology [bioRxiv] 2025 Feb 09. Date of Electronic Publication: 2025 Feb 09. |
| Publication Type: | Journal Article; Preprint |
| Journal Info: | Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 39975170 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: AI-assisted protein design to rapidly convert antibody sequences to intrabodies targeting diverse peptides and histone modifications. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Galindo+G%22">Galindo G</searchLink>; Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO, USA.<br /><searchLink fieldCode="AU" term="%22Maejima+D%22">Maejima D</searchLink>; School of Life Science and Technology, Institute of Science Tokyo, Yokohama, Japan.<br /><searchLink fieldCode="AU" term="%22DeRoo+J%22">DeRoo J</searchLink>; School of Biomedical Engineering, Colorado State University, Fort Collins, CO, USA.<br /><searchLink fieldCode="AU" term="%22Burlingham+SR%22">Burlingham SR</searchLink>; Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO, USA.<br /><searchLink fieldCode="AU" term="%22Fixen+G%22">Fixen G</searchLink>; Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO, USA.<br /><searchLink fieldCode="AU" term="%22Morisaki+T%22">Morisaki T</searchLink>; Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO, USA.<br /><searchLink fieldCode="AU" term="%22Febvre+HP%22">Febvre HP</searchLink>; Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO, USA.<br /><searchLink fieldCode="AU" term="%22Hasbrook+R%22">Hasbrook R</searchLink>; Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO, USA.<br /><searchLink fieldCode="AU" term="%22Zhao+N%22">Zhao N</searchLink>; Department of Biochemistry and Molecular Genetics, University of Colorado-Anschutz Medical Campus, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22Ghosh+S%22">Ghosh S</searchLink>; School of Biomedical Engineering, Colorado State University, Fort Collins, CO, USA.; Department of Mechanical Engineering, Colorado State University, Fort Collins, CO, USA.<br /><searchLink fieldCode="AU" term="%22Mayton+EH%22">Mayton EH</searchLink>; Department of Microbiology, Immunology, & Pathology, Colorado State University, Fort Collins, CO, USA.<br /><searchLink fieldCode="AU" term="%22Snow+CD%22">Snow CD</searchLink>; Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO, USA.; School of Biomedical Engineering, Colorado State University, Fort Collins, CO, USA.; Department of Chemical & Biological Engineering, Colorado State University, Fort Collins, CO, USA.<br /><searchLink fieldCode="AU" term="%22Geiss+BJ%22">Geiss BJ</searchLink>; School of Biomedical Engineering, Colorado State University, Fort Collins, CO, USA.; Department of Microbiology, Immunology, & Pathology, Colorado State University, Fort Collins, CO, USA.<br /><searchLink fieldCode="AU" term="%22Ohkawa+Y%22">Ohkawa Y</searchLink>; Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.<br /><searchLink fieldCode="AU" term="%22Sato+Y%22">Sato Y</searchLink>; Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.; Cell Biology Center, Institute of Innovative Research, Tokyo Institute of Technology, Yokohama, Japan.<br /><searchLink fieldCode="AU" term="%22Kimura+H%22">Kimura H</searchLink>; School of Life Science and Technology, Institute of Science Tokyo, Yokohama, Japan.; Cell Biology Center, Institute of Innovative Research, Tokyo Institute of Technology, Yokohama, Japan.; Cell Biology Center, Institute of Integrated Research, Institute of Science Tokyo, Yokohama, Japan.<br /><searchLink fieldCode="AU" term="%22Stasevich+TJ%22">Stasevich TJ</searchLink>; Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO, USA.; School of Biomedical Engineering, Colorado State University, Fort Collins, CO, USA.; Department of Chemical & Biological Engineering, Colorado State University, Fort Collins, CO, USA.; Cell Biology Center, Institute of Integrated Research, Institute of Science Tokyo, Yokohama, Japan. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101680187%22">BioRxiv : the preprint server for biology</searchLink> [bioRxiv] 2025 Feb 09. <i>Date of Electronic Publication: </i>2025 Feb 09. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Preprint – Name: TitleSource Label: Journal Info Group: Src Data: <i>Country of Publication: </i>United States <i>NLM ID: </i>101680187 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2692-8205 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226928205%22">26928205 </searchLink><i>NLM ISO Abbreviation: </i>bioRxiv <i>Subsets: </i>PubMed not MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=39975170 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1101/2025.02.06.636921 Languages: – Code: eng Text: English Titles: – TitleFull: AI-assisted protein design to rapidly convert antibody sequences to intrabodies targeting diverse peptides and histone modifications. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Galindo G – PersonEntity: Name: NameFull: Maejima D – PersonEntity: Name: NameFull: DeRoo J – PersonEntity: Name: NameFull: Burlingham SR – PersonEntity: Name: NameFull: Fixen G – PersonEntity: Name: NameFull: Morisaki T – PersonEntity: Name: NameFull: Febvre HP – PersonEntity: Name: NameFull: Hasbrook R – PersonEntity: Name: NameFull: Zhao N – PersonEntity: Name: NameFull: Ghosh S – PersonEntity: Name: NameFull: Mayton EH – PersonEntity: Name: NameFull: Snow CD – PersonEntity: Name: NameFull: Geiss BJ – PersonEntity: Name: NameFull: Ohkawa Y – PersonEntity: Name: NameFull: Sato Y – PersonEntity: Name: NameFull: Kimura H – PersonEntity: Name: NameFull: Stasevich TJ IsPartOfRelationships: – BibEntity: Dates: – D: 09 M: 02 Text: 2025 Feb 09 Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 2692-8205 Titles: – TitleFull: BioRxiv : the preprint server for biology Type: main |
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