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Metabolic Adaptations Rewire CD4 T Cells in a Subset-Specific Manner in Human Critical Illness with and without Sepsis.

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Title: Metabolic Adaptations Rewire CD4 T Cells in a Subset-Specific Manner in Human Critical Illness with and without Sepsis.
Authors: Stier MT; Division of Allergy, Pulmonary & Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States.; Vanderbilt Center for Immunobiology, Vanderbilt University Medical Center, Nashville, TN, United States., Sewell AE; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, United States., Mwizerwa EL; Division of Allergy, Pulmonary & Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States., Sim CY; Division of Allergy, Pulmonary & Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States., Tanner SM; Division of Allergy, Pulmonary & Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States., Nichols CM; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, United States., Durai HH; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, United States., Jennings EQ; Division of Hematology and Oncology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States., Lindau P; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States., Wilfong EM; Division of Allergy, Pulmonary & Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States.; Vanderbilt Center for Immunobiology, Vanderbilt University Medical Center, Nashville, TN, United States.; Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States., Newcomb DC; Division of Allergy, Pulmonary & Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States.; Vanderbilt Center for Immunobiology, Vanderbilt University Medical Center, Nashville, TN, United States.; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, United States., Bastarache JA; Division of Allergy, Pulmonary & Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States.; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, United States.; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN, United States., Ware LB; Division of Allergy, Pulmonary & Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States.; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, United States., Rathmell JC; Vanderbilt Center for Immunobiology, Vanderbilt University Medical Center, Nashville, TN, United States.; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, United States.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Jan 29. Date of Electronic Publication: 2025 Jan 29.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Metabolic Adaptations Rewire CD4 T Cells in a Subset-Specific Manner in Human Critical Illness with and without Sepsis.
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  Data: <searchLink fieldCode="AU" term="%22Stier+MT%22">Stier MT</searchLink>; Division of Allergy, Pulmonary & Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States.; Vanderbilt Center for Immunobiology, Vanderbilt University Medical Center, Nashville, TN, United States.<br /><searchLink fieldCode="AU" term="%22Sewell+AE%22">Sewell AE</searchLink>; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, United States.<br /><searchLink fieldCode="AU" term="%22Mwizerwa+EL%22">Mwizerwa EL</searchLink>; Division of Allergy, Pulmonary & Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States.<br /><searchLink fieldCode="AU" term="%22Sim+CY%22">Sim CY</searchLink>; Division of Allergy, Pulmonary & Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States.<br /><searchLink fieldCode="AU" term="%22Tanner+SM%22">Tanner SM</searchLink>; Division of Allergy, Pulmonary & Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States.<br /><searchLink fieldCode="AU" term="%22Nichols+CM%22">Nichols CM</searchLink>; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, United States.<br /><searchLink fieldCode="AU" term="%22Durai+HH%22">Durai HH</searchLink>; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, United States.<br /><searchLink fieldCode="AU" term="%22Jennings+EQ%22">Jennings EQ</searchLink>; Division of Hematology and Oncology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States.<br /><searchLink fieldCode="AU" term="%22Lindau+P%22">Lindau P</searchLink>; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States.<br /><searchLink fieldCode="AU" term="%22Wilfong+EM%22">Wilfong EM</searchLink>; Division of Allergy, Pulmonary & Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States.; Vanderbilt Center for Immunobiology, Vanderbilt University Medical Center, Nashville, TN, United States.; Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States.<br /><searchLink fieldCode="AU" term="%22Newcomb+DC%22">Newcomb DC</searchLink>; Division of Allergy, Pulmonary & Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States.; Vanderbilt Center for Immunobiology, Vanderbilt University Medical Center, Nashville, TN, United States.; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, United States.<br /><searchLink fieldCode="AU" term="%22Bastarache+JA%22">Bastarache JA</searchLink>; Division of Allergy, Pulmonary & Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States.; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, United States.; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN, United States.<br /><searchLink fieldCode="AU" term="%22Ware+LB%22">Ware LB</searchLink>; Division of Allergy, Pulmonary & Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States.; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, United States.<br /><searchLink fieldCode="AU" term="%22Rathmell+JC%22">Rathmell JC</searchLink>; Vanderbilt Center for Immunobiology, Vanderbilt University Medical Center, Nashville, TN, United States.; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, United States.
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