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Adaptive decision support for addiction treatment to implement initiation of buprenorphine for opioid use disorder in the emergency department: protocol for the ADAPT Multiphase Optimization Strategy trial.

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Title: Adaptive decision support for addiction treatment to implement initiation of buprenorphine for opioid use disorder in the emergency department: protocol for the ADAPT Multiphase Optimization Strategy trial.
Authors: Iscoe MS; Department of Emergency Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.; Department of Biomedical Informatics and Data Sciences, Yale University School of Medicine, New Haven, Connecticut, USA., Diniz Hooper C; Department of Emergency Medicine, Yale University School of Medicine, New Haven, Connecticut, USA., Levy DR; Department of Biomedical Informatics and Data Sciences, Yale University School of Medicine, New Haven, Connecticut, USA.; Department of Veterans Affairs, VA Connecticut Healthcare System-West Haven Campus, West Haven, Connecticut, USA., Buchanan L; Department of Emergency Medicine, Yale University School of Medicine, New Haven, Connecticut, USA., Dziura J; Department of Emergency Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.; Yale University School of Public Health, New Haven, Connecticut, USA., Meeker D; Department of Biomedical Informatics and Data Sciences, Yale University School of Medicine, New Haven, Connecticut, USA., Taylor RA; Department of Emergency Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.; Department of Biomedical Informatics and Data Sciences, Yale University School of Medicine, New Haven, Connecticut, USA., D'Onofrio G; Department of Emergency Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.; Yale University School of Public Health, New Haven, Connecticut, USA.; Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA., Oladele C; Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.; Equity Research and Innovation Center, Yale University School of Medicine, New Haven, Connecticut, USA., Sarpong DF; Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.; Equity Research and Innovation Center, Yale University School of Medicine, New Haven, Connecticut, USA., Paek H; Digital & Technology Solutions, Yale New-Haven Health, New Haven, Connecticut, USA., Wilson FP; Program of Applied Translational Research, Yale University School of Medicine, New Haven, Connecticut, USA.; Section of Nephrology, Department of Medicine, Yale University School of Medicine, New Haven, Connecticut, USA., Heagerty PJ; Department of Biostatistics, University of Washington, Seattle, Washington, USA., Delgado MK; Department of Emergency Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA., Hoppe J; Department of Emergency Medicine, University of Colorado School of Medicine, Aurora, Colorado, USA., Melnick ER; Department of Emergency Medicine, Yale University School of Medicine, New Haven, Connecticut, USA edward.melnick@yale.edu.; Department of Biomedical Informatics and Data Sciences, Yale University School of Medicine, New Haven, Connecticut, USA.; Yale University School of Public Health, New Haven, Connecticut, USA.
Source: BMJ open [BMJ Open] 2025 Feb 20; Vol. 15 (2), pp. e098072. Date of Electronic Publication: 2025 Feb 20.
Publication Type: Journal Article; Clinical Trial Protocol
Journal Info: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101552874 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-6055 (Electronic) Linking ISSN: 20446055 NLM ISO Abbreviation: BMJ Open Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Iscoe+MS%22">Iscoe MS</searchLink>; Department of Emergency Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.; Department of Biomedical Informatics and Data Sciences, Yale University School of Medicine, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Diniz+Hooper+C%22">Diniz Hooper C</searchLink>; Department of Emergency Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Levy+DR%22">Levy DR</searchLink>; Department of Biomedical Informatics and Data Sciences, Yale University School of Medicine, New Haven, Connecticut, USA.; Department of Veterans Affairs, VA Connecticut Healthcare System-West Haven Campus, West Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Buchanan+L%22">Buchanan L</searchLink>; Department of Emergency Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Dziura+J%22">Dziura J</searchLink>; Department of Emergency Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.; Yale University School of Public Health, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Meeker+D%22">Meeker D</searchLink>; Department of Biomedical Informatics and Data Sciences, Yale University School of Medicine, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Taylor+RA%22">Taylor RA</searchLink>; Department of Emergency Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.; Department of Biomedical Informatics and Data Sciences, Yale University School of Medicine, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22D'Onofrio+G%22">D'Onofrio G</searchLink>; Department of Emergency Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.; Yale University School of Public Health, New Haven, Connecticut, USA.; Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Oladele+C%22">Oladele C</searchLink>; Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.; Equity Research and Innovation Center, Yale University School of Medicine, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Sarpong+DF%22">Sarpong DF</searchLink>; Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.; Equity Research and Innovation Center, Yale University School of Medicine, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Paek+H%22">Paek H</searchLink>; Digital & Technology Solutions, Yale New-Haven Health, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Wilson+FP%22">Wilson FP</searchLink>; Program of Applied Translational Research, Yale University School of Medicine, New Haven, Connecticut, USA.; Section of Nephrology, Department of Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Heagerty+PJ%22">Heagerty PJ</searchLink>; Department of Biostatistics, University of Washington, Seattle, Washington, USA.<br /><searchLink fieldCode="AU" term="%22Delgado+MK%22">Delgado MK</searchLink>; Department of Emergency Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Hoppe+J%22">Hoppe J</searchLink>; Department of Emergency Medicine, University of Colorado School of Medicine, Aurora, Colorado, USA.<br /><searchLink fieldCode="AU" term="%22Melnick+ER%22">Melnick ER</searchLink>; Department of Emergency Medicine, Yale University School of Medicine, New Haven, Connecticut, USA edward.melnick@yale.edu.; Department of Biomedical Informatics and Data Sciences, Yale University School of Medicine, New Haven, Connecticut, USA.; Yale University School of Public Health, New Haven, Connecticut, USA.
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