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Activation of CAMK2 by pseudokinase PEAK1 represents a targetable pathway in triple negative breast cancer.

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Title: Activation of CAMK2 by pseudokinase PEAK1 represents a targetable pathway in triple negative breast cancer.
Authors: Yang X; Cancer Program, Monash Biomedicine Discovery Institute, Clayton, VIC, Australia.; Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC, Australia., Ma X; Cancer Program, Monash Biomedicine Discovery Institute, Clayton, VIC, Australia.; Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC, Australia., Zhao T; Cancer Program, Monash Biomedicine Discovery Institute, Clayton, VIC, Australia.; Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC, Australia., Croucher DR; Garvan Institute of Medical Research, Darlinghurst, NSW, Australia.; St Vincent's Clinical School, Faculty of Medicine, UNSW Sydney, Darlinghurst, NSW, Australia., Nguyen EV; Cancer Program, Monash Biomedicine Discovery Institute, Clayton, VIC, Australia.; Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC, Australia., Clark KC; Cancer Program, Monash Biomedicine Discovery Institute, Clayton, VIC, Australia.; Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC, Australia., Hu C; Cancer Program, Monash Biomedicine Discovery Institute, Clayton, VIC, Australia.; Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC, Australia., Latham SL; Garvan Institute of Medical Research, Darlinghurst, NSW, Australia.; St Vincent's Clinical School, Faculty of Medicine, UNSW Sydney, Darlinghurst, NSW, Australia., Bayly-Jones C; Cancer Program, Monash Biomedicine Discovery Institute, Clayton, VIC, Australia.; Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC, Australia., Nguyen BV; Department of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, MA, USA., Budnar S; Cancer Program, Monash Biomedicine Discovery Institute, Clayton, VIC, Australia.; Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC, Australia., Shin SY; Cancer Program, Monash Biomedicine Discovery Institute, Clayton, VIC, Australia.; Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC, Australia., Nguyen LK; Cancer Program, Monash Biomedicine Discovery Institute, Clayton, VIC, Australia.; Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC, Australia.; South Australian Immunogenomics Cancer Institute, University of Adelaide, Adelaide, Australia., Cotton TR; Cancer Program, Monash Biomedicine Discovery Institute, Clayton, VIC, Australia.; Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC, Australia., Chüeh AC; Cancer Program, Monash Biomedicine Discovery Institute, Clayton, VIC, Australia.; Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC, Australia., Lim Kam Sian TCC; Cancer Program, Monash Biomedicine Discovery Institute, Clayton, VIC, Australia.; Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC, Australia., Stratton MM; Department of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, MA, USA., Ellisdon AM; Cancer Program, Monash Biomedicine Discovery Institute, Clayton, VIC, Australia.; Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC, Australia., Daly RJ; Cancer Program, Monash Biomedicine Discovery Institute, Clayton, VIC, Australia. roger.daly@monash.edu.; Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC, Australia. roger.daly@monash.edu.
Source: Nature communications [Nat Commun] 2025 Feb 22; Vol. 16 (1), pp. 1871. Date of Electronic Publication: 2025 Feb 22.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Activation of CAMK2 by pseudokinase PEAK1 represents a targetable pathway in triple negative breast cancer.
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  Data: <searchLink fieldCode="AU" term="%22Yang+X%22">Yang X</searchLink>; Cancer Program, Monash Biomedicine Discovery Institute, Clayton, VIC, Australia.; Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Ma+X%22">Ma X</searchLink>; Cancer Program, Monash Biomedicine Discovery Institute, Clayton, VIC, Australia.; Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Zhao+T%22">Zhao T</searchLink>; Cancer Program, Monash Biomedicine Discovery Institute, Clayton, VIC, Australia.; Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Croucher+DR%22">Croucher DR</searchLink>; Garvan Institute of Medical Research, Darlinghurst, NSW, Australia.; St Vincent's Clinical School, Faculty of Medicine, UNSW Sydney, Darlinghurst, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Nguyen+EV%22">Nguyen EV</searchLink>; Cancer Program, Monash Biomedicine Discovery Institute, Clayton, VIC, Australia.; Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Clark+KC%22">Clark KC</searchLink>; Cancer Program, Monash Biomedicine Discovery Institute, Clayton, VIC, Australia.; Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Hu+C%22">Hu C</searchLink>; Cancer Program, Monash Biomedicine Discovery Institute, Clayton, VIC, Australia.; Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Latham+SL%22">Latham SL</searchLink>; Garvan Institute of Medical Research, Darlinghurst, NSW, Australia.; St Vincent's Clinical School, Faculty of Medicine, UNSW Sydney, Darlinghurst, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Bayly-Jones+C%22">Bayly-Jones C</searchLink>; Cancer Program, Monash Biomedicine Discovery Institute, Clayton, VIC, Australia.; Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Nguyen+BV%22">Nguyen BV</searchLink>; Department of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, MA, USA.<br /><searchLink fieldCode="AU" term="%22Budnar+S%22">Budnar S</searchLink>; Cancer Program, Monash Biomedicine Discovery Institute, Clayton, VIC, Australia.; Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Shin+SY%22">Shin SY</searchLink>; Cancer Program, Monash Biomedicine Discovery Institute, Clayton, VIC, Australia.; Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Nguyen+LK%22">Nguyen LK</searchLink>; Cancer Program, Monash Biomedicine Discovery Institute, Clayton, VIC, Australia.; Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC, Australia.; South Australian Immunogenomics Cancer Institute, University of Adelaide, Adelaide, Australia.<br /><searchLink fieldCode="AU" term="%22Cotton+TR%22">Cotton TR</searchLink>; Cancer Program, Monash Biomedicine Discovery Institute, Clayton, VIC, Australia.; Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Chüeh+AC%22">Chüeh AC</searchLink>; Cancer Program, Monash Biomedicine Discovery Institute, Clayton, VIC, Australia.; Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Lim+Kam+Sian+TCC%22">Lim Kam Sian TCC</searchLink>; Cancer Program, Monash Biomedicine Discovery Institute, Clayton, VIC, Australia.; Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Stratton+MM%22">Stratton MM</searchLink>; Department of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, MA, USA.<br /><searchLink fieldCode="AU" term="%22Ellisdon+AM%22">Ellisdon AM</searchLink>; Cancer Program, Monash Biomedicine Discovery Institute, Clayton, VIC, Australia.; Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Daly+RJ%22">Daly RJ</searchLink>; Cancer Program, Monash Biomedicine Discovery Institute, Clayton, VIC, Australia. roger.daly@monash.edu.; Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC, Australia. roger.daly@monash.edu.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2025 Feb 22; Vol. 16 (1), pp. 1871. <i>Date of Electronic Publication: </i>2025 Feb 22.
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      – TitleFull: Activation of CAMK2 by pseudokinase PEAK1 represents a targetable pathway in triple negative breast cancer.
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