Crystallographic fragment screening and deep mutational scanning of Zika virus NS2B-NS3 protease enable development of resistance-resilient inhibitors.
Saved in:
| Title: | Crystallographic fragment screening and deep mutational scanning of Zika virus NS2B-NS3 protease enable development of resistance-resilient inhibitors. |
|---|---|
| Authors: | von Delft F; Diamond Light Source., Ni X; University of Oxford., Richardson R; University of Texas Southwestern Medical Center., Godoy A; University of Sao Paulo., Ferla M; University of Oxford., Kikawa C; University of Washington., Scheen J; Open Molecular Software Foundation., Hannon W; Fred Hutch Cancer Center., Capkin E; Diamond Light Source., Lahav N; The Wohl Drug Discovery Institute of the Nancy and Stephen Grand Israel National Center for Personalized Medicine, Weizmann Institute of Science., Balcomb B; Diamond Light Source., Marples P; Diamond Light Source Ltd., Fairhead M; Centre for Medicines Discovery, University of Oxford., Wang S; University of Oxford., Williams E; University of Oxford., Tomlinson C; Diamond Light Source., Aschenbrenner J; Diamond Light Source Ltd., Lithgo R; Diamond Light Source., Winokan M; Diamond Light Source Ltd., Giroud C; University of Oxford., Chandran A; Diamond Light Source., Walsh M; Diamond Light Source., Thompson W; Diamond Light Source, UK., Bloom J; Fred Hutchinson Cancer Center., Barr H; Weizmann Institute of Science., Kirkegaard K; Stanford University., Koekemoer L; Oxford University., Fearon D; Diamond Light Source., Evans M; Icahn School of Medicine at Mount Sinai. |
| Source: | Research square [Res Sq] 2025 Feb 13. Date of Electronic Publication: 2025 Feb 13. |
| Publication Type: | Journal Article; Preprint |
| Journal Info: | Country of Publication: United States NLM ID: 101768035 Publication Model: Electronic Cited Medium: Internet ISSN: 2693-5015 (Electronic) Linking ISSN: 26935015 NLM ISO Abbreviation: Res Sq Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
Be the first to leave a comment!
