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Nuclear regulatory disturbances precede and predict the development of Type-2 diabetes in Asian populations.

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Title: Nuclear regulatory disturbances precede and predict the development of Type-2 diabetes in Asian populations.
Authors: Jain PR; Population and Global Health, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore., Ng HK; Population and Global Health, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore., Tay D; Population and Global Health, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore., Mina T; Population and Global Health, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore., Low D; Population and Global Health, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore., Sadhu N; Population and Global Health, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore., Kooner IK; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, United Kingdom., Gupta A; Population and Global Health, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore., Li TF; Population and Global Health, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore., Bertin N; Precision Health Research (PRECISE), Singapore.; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore., Chin CWL; National Heart Centre Singapore, Singapore., Fang CJ; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore., Goh LL; Personalised Medicine Service, Tan Tock Seng Hospital, Singapore., Mok SQ; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore., Peh SQ; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore., Sabanayagam C; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.; Ophthalmology & Visual Sciences Academic Clinical Program, Duke-NUS Medical School, Singapore., Jha V; Max Healthcare Institute, New Delhi, India., Kasturiratne A; University of Kelaniya, Kelaniya, Sri Lanka., Katulanda P; University of Colombo, Colombo, Sri Lanka., Khawaja KI; Services Institute for Medical Science, Lahore, Pakistan., Lim WK; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore.; SingHealth Duke-NUS Institute of Precision Medicine, Singapore.; SingHealth Duke-NUS Genomic Medicine Centre, Singapore.; Cancer & Stem Cell Biology Program, Duke-NUS Medical School, Singapore., Leong KP; Personalised Medicine Service, Tan Tock Seng Hospital, Singapore., Cheng CY; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.; Centre for Innovation and Precision Eye Health, Yong Loo Lin School of Medicine, National University of Singapore.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Yuan JM; University of Pittsburgh Medical Center Hillman Cancer Center, Pittsburgh, PA, USA.; Department of Epidemiology, School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA., Elliott P; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, United Kingdom., Riboli E; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, United Kingdom., Sing LE; Population and Global Health, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore., Lee J; Population and Global Health, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore.; Institute of Mental Health, Singapore., Ngeow J; Population and Global Health, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore.; Division of Medical Oncology, National Cancer Centre, Singapore., Liu JJ; Human Genomics, Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Best J; Melbourne Medical School, University of Melbourne, Australia.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore., Kooner JS; Department of Cardiology, Ealing Hospital, London North West Healthcare NHS Trust, Middlesex, United Kingdom.; Imperial College Healthcare NHS Trust, Imperial College London, London, United Kingdom.; Medical Research Council-Public Health England Centre for Environment and Health, Imperial College London, London, United Kingdom.; National Heart and Lung Institute, Imperial College London, London, United Kingdom., Tai ES; Precision Health Research (PRECISE), Singapore.; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.; Division of Endocrinology, National University Hospital, Singapore., Tan P; Precision Health Research (PRECISE), Singapore.; Duke-NUS Medical School, Singapore., van Dam RM; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.; Department of Exercise and Nutrition Sciences, Milken Institute School of Public Health, The George Washington University, Washington DC, USA., Koh WP; Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Singapore Institute for Clinical Sciences, Agency for Science, Technology and Research, Singapore., Xueling S; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore., Loh M; Population and Global Health, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore.; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, United Kingdom.; National Skin Centre, Research Division, Singapore., Chambers JC; Population and Global Health, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore.; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, United Kingdom.; Precision Health Research (PRECISE), Singapore.
Source: MedRxiv : the preprint server for health sciences [medRxiv] 2025 Feb 14. Date of Electronic Publication: 2025 Feb 14.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101767986 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: medRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
FullText Text:
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