Higher target attainment for B-lactam antibiotics in patients with Gram-negative bloodstream infections when four times actual minimum inhibitory concentrations and epidemiological cutoff values are applied compared to clinical breakpoints.
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| Title: | Higher target attainment for B-lactam antibiotics in patients with Gram-negative bloodstream infections when four times actual minimum inhibitory concentrations and epidemiological cutoff values are applied compared to clinical breakpoints. |
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| Authors: | Lejbman IA; Department of Intensive and Perioperative Care, Skåne University Hospital, Carl-Bertil Laurells gata 9, Malmö, 205 02, Sweden. ilja.areskog_lejbman@med.lu.se.; Department of Clinical Sciences, Lund university, Lund, Sweden. ilja.areskog_lejbman@med.lu.se., Torisson G; Department of Infectious Diseases, Skåne University Hospital, Malmö, Sweden.; Clinical Infection Medicine, Dept of Translational Medicine, Lund University, Lund, Sweden., Resman F; Department of Infectious Diseases, Skåne University Hospital, Malmö, Sweden.; Clinical Infection Medicine, Dept of Translational Medicine, Lund University, Lund, Sweden., Sjövall F; Department of Intensive and Perioperative Care, Skåne University Hospital, Carl-Bertil Laurells gata 9, Malmö, 205 02, Sweden.; Department of Clinical Sciences, Lund university, Lund, Sweden. |
| Source: | European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology [Eur J Clin Microbiol Infect Dis] 2025 May; Vol. 44 (5), pp. 1129-1137. Date of Electronic Publication: 2025 Feb 24. |
| Publication Type: | Journal Article; Comparative Study |
| Journal Info: | Publisher: Springer Country of Publication: Germany NLM ID: 8804297 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1435-4373 (Electronic) Linking ISSN: 09349723 NLM ISO Abbreviation: Eur J Clin Microbiol Infect Dis Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1435-4373 |
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| DOI: | 10.1007/s10096-025-05068-x |
