Higher target attainment for B-lactam antibiotics in patients with Gram-negative bloodstream infections when four times actual minimum inhibitory concentrations and epidemiological cutoff values are applied compared to clinical breakpoints.

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Title: Higher target attainment for B-lactam antibiotics in patients with Gram-negative bloodstream infections when four times actual minimum inhibitory concentrations and epidemiological cutoff values are applied compared to clinical breakpoints.
Authors: Lejbman IA; Department of Intensive and Perioperative Care, Skåne University Hospital, Carl-Bertil Laurells gata 9, Malmö, 205 02, Sweden. ilja.areskog_lejbman@med.lu.se.; Department of Clinical Sciences, Lund university, Lund, Sweden. ilja.areskog_lejbman@med.lu.se., Torisson G; Department of Infectious Diseases, Skåne University Hospital, Malmö, Sweden.; Clinical Infection Medicine, Dept of Translational Medicine, Lund University, Lund, Sweden., Resman F; Department of Infectious Diseases, Skåne University Hospital, Malmö, Sweden.; Clinical Infection Medicine, Dept of Translational Medicine, Lund University, Lund, Sweden., Sjövall F; Department of Intensive and Perioperative Care, Skåne University Hospital, Carl-Bertil Laurells gata 9, Malmö, 205 02, Sweden.; Department of Clinical Sciences, Lund university, Lund, Sweden.
Source: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology [Eur J Clin Microbiol Infect Dis] 2025 May; Vol. 44 (5), pp. 1129-1137. Date of Electronic Publication: 2025 Feb 24.
Publication Type: Journal Article; Comparative Study
Journal Info: Publisher: Springer Country of Publication: Germany NLM ID: 8804297 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1435-4373 (Electronic) Linking ISSN: 09349723 NLM ISO Abbreviation: Eur J Clin Microbiol Infect Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Higher target attainment for B-lactam antibiotics in patients with Gram-negative bloodstream infections when four times actual minimum inhibitory concentrations and epidemiological cutoff values are applied compared to clinical breakpoints.
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  Data: <searchLink fieldCode="AU" term="%22Lejbman+IA%22">Lejbman IA</searchLink>; Department of Intensive and Perioperative Care, Skåne University Hospital, Carl-Bertil Laurells gata 9, Malmö, 205 02, Sweden. ilja.areskog_lejbman@med.lu.se.; Department of Clinical Sciences, Lund university, Lund, Sweden. ilja.areskog_lejbman@med.lu.se.<br /><searchLink fieldCode="AU" term="%22Torisson+G%22">Torisson G</searchLink>; Department of Infectious Diseases, Skåne University Hospital, Malmö, Sweden.; Clinical Infection Medicine, Dept of Translational Medicine, Lund University, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Resman+F%22">Resman F</searchLink>; Department of Infectious Diseases, Skåne University Hospital, Malmö, Sweden.; Clinical Infection Medicine, Dept of Translational Medicine, Lund University, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Sjövall+F%22">Sjövall F</searchLink>; Department of Intensive and Perioperative Care, Skåne University Hospital, Carl-Bertil Laurells gata 9, Malmö, 205 02, Sweden.; Department of Clinical Sciences, Lund university, Lund, Sweden.
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  Data: <searchLink fieldCode="JN" term="%228804297%22">European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology</searchLink> [Eur J Clin Microbiol Infect Dis] 2025 May; Vol. 44 (5), pp. 1129-1137. <i>Date of Electronic Publication: </i>2025 Feb 24.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer%22">Springer </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>8804297 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1435-4373 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209349723%22">09349723 </searchLink><i>NLM ISO Abbreviation: </i>Eur J Clin Microbiol Infect Dis <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s10096-025-05068-x
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              Text: 2025 May
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