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RORγt-expressing dendritic cells are functionally versatile and evolutionarily conserved antigen-presenting cells.

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Title: RORγt-expressing dendritic cells are functionally versatile and evolutionarily conserved antigen-presenting cells.
Authors: Narasimhan H; Institute for Immunology, Biomedical Center Munich, Faculty of Medicine, Ludwig-Maximilians-Universität in Munich, Planegg-Martinsried 82152, Germany.; Biomedical Center, Institute of Cardiovascular Physiology and Pathophysiology, Faculty of Medicine, Ludwig-Maximilians-Universität in Munich, Planegg-Martinsried 82152, Germany., Richter ML; Biomedical Center, Physiological Chemistry, Faculty of Medicine, Ludwig-Maximilians-Universität in Munich, Planegg-Martinsried 82152, Germany., Shakiba R; Institute for Immunology, Biomedical Center Munich, Faculty of Medicine, Ludwig-Maximilians-Universität in Munich, Planegg-Martinsried 82152, Germany.; Biomedical Center, Institute of Cardiovascular Physiology and Pathophysiology, Faculty of Medicine, Ludwig-Maximilians-Universität in Munich, Planegg-Martinsried 82152, Germany., Papaioannou NE; Biomedical Center, Institute of Cardiovascular Physiology and Pathophysiology, Faculty of Medicine, Ludwig-Maximilians-Universität in Munich, Planegg-Martinsried 82152, Germany., Stehle C; Institute for Medical Immunology, Charité Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt Universität zu Berlin, Berlin 10117, Germany., Ravi Rengarajan K; Institute for Immunology, Biomedical Center Munich, Faculty of Medicine, Ludwig-Maximilians-Universität in Munich, Planegg-Martinsried 82152, Germany.; Biomedical Center, Institute of Cardiovascular Physiology and Pathophysiology, Faculty of Medicine, Ludwig-Maximilians-Universität in Munich, Planegg-Martinsried 82152, Germany., Ulmert I; Section for Experimental and Translational Immunology, Institute for Health Technology, Technical University of Denmark, Kongens Lyngby 2800, Denmark., Kendirli A; Institute of Clinical Neuroimmunology, University Hospital, Ludwig-Maximilians-Universität in Munich, Planegg-Martinsried 82152, Germany.; Biomedical Center, Medical Faculty, Ludwig-Maximilians-Universität in Munich, Planegg-Martinsried 82152, Germany.; Munich Cluster of Systems Neurology (SyNergy), Munich 81377, Germany., de la Rosa C; Institute of Clinical Neuroimmunology, University Hospital, Ludwig-Maximilians-Universität in Munich, Planegg-Martinsried 82152, Germany.; Biomedical Center, Medical Faculty, Ludwig-Maximilians-Universität in Munich, Planegg-Martinsried 82152, Germany.; Graduate School of Systemic Neurosciences, LMU, Planegg-Martinsried 82152, Germany., Kuo PY; Institute for Immunology, Biomedical Center Munich, Faculty of Medicine, Ludwig-Maximilians-Universität in Munich, Planegg-Martinsried 82152, Germany.; Biomedical Center, Institute of Cardiovascular Physiology and Pathophysiology, Faculty of Medicine, Ludwig-Maximilians-Universität in Munich, Planegg-Martinsried 82152, Germany., Altman A; Molecular Medicine and Gene Therapy, Lund Stem Cell Centre, Lund University, Lund 221 84, Sweden.; Wallenberg Centre for Molecular Medicine at Lund University, Lund 221 84, Sweden., Münch P; Institute for Molecular Medicine and Research Center for Immunotherapy (Forschungszentrum für Immuntherapie), University Medical Center Johannes Gutenberg-University Mainz, Mainz 55131, Germany., Mahboubi S; Institute for Molecular Medicine and Research Center for Immunotherapy (Forschungszentrum für Immuntherapie), University Medical Center Johannes Gutenberg-University Mainz, Mainz 55131, Germany., Küntzel V; Biomedical Center, Institute of Cardiovascular Physiology and Pathophysiology, Faculty of Medicine, Ludwig-Maximilians-Universität in Munich, Planegg-Martinsried 82152, Germany., Sayed A; Institute for Immunology, Biomedical Center Munich, Faculty of Medicine, Ludwig-Maximilians-Universität in Munich, Planegg-Martinsried 82152, Germany., Stange EL; Institute of Medical Microbiology, Rheinisch-Westfälische Technische Hochschule Aachen University Hospital, Aachen 52074, Germany., Pes J; Institute of Medical Microbiology, Rheinisch-Westfälische Technische Hochschule Aachen University Hospital, Aachen 52074, Germany., Ulezko Antonova A; Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO 63110., Pereira CF; Molecular Medicine and Gene Therapy, Lund Stem Cell Centre, Lund University, Lund 221 84, Sweden.; Wallenberg Centre for Molecular Medicine at Lund University, Lund 221 84, Sweden., Klein L; Institute for Immunology, Biomedical Center Munich, Faculty of Medicine, Ludwig-Maximilians-Universität in Munich, Planegg-Martinsried 82152, Germany., Dudziak D; Institute of Immunology, Jena University Hospital of the Friedrich-Schiller-University, Jena 07747, Germany., Colonna M; Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO 63110., Torow N; Institute of Medical Microbiology, Rheinisch-Westfälische Technische Hochschule Aachen University Hospital, Aachen 52074, Germany., Hornef MW; Institute of Medical Microbiology, Rheinisch-Westfälische Technische Hochschule Aachen University Hospital, Aachen 52074, Germany., Clausen BE; Institute for Molecular Medicine and Research Center for Immunotherapy (Forschungszentrum für Immuntherapie), University Medical Center Johannes Gutenberg-University Mainz, Mainz 55131, Germany., Kerschensteiner M; Institute of Clinical Neuroimmunology, University Hospital, Ludwig-Maximilians-Universität in Munich, Planegg-Martinsried 82152, Germany.; Biomedical Center, Medical Faculty, Ludwig-Maximilians-Universität in Munich, Planegg-Martinsried 82152, Germany.; Munich Cluster of Systems Neurology (SyNergy), Munich 81377, Germany., Lahl K; Section for Experimental and Translational Immunology, Institute for Health Technology, Technical University of Denmark, Kongens Lyngby 2800, Denmark.; Immunology Section, Lund University, Lund 221 84, Sweden.; Calvin, Phoebe and Joan Snyder Institute for Chronic Diseases, University of Calgary, Calgary, AB T2N 1N4, Canada.; Department of Microbiology, Immunology, and Infectious Diseases, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 1N4, Canada., Romagnani C; Institute for Medical Immunology, Charité Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt Universität zu Berlin, Berlin 10117, Germany., Colomé-Tatché M; Biomedical Center, Physiological Chemistry, Faculty of Medicine, Ludwig-Maximilians-Universität in Munich, Planegg-Martinsried 82152, Germany., Schraml BU; Institute for Immunology, Biomedical Center Munich, Faculty of Medicine, Ludwig-Maximilians-Universität in Munich, Planegg-Martinsried 82152, Germany.; Biomedical Center, Institute of Cardiovascular Physiology and Pathophysiology, Faculty of Medicine, Ludwig-Maximilians-Universität in Munich, Planegg-Martinsried 82152, Germany.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2025 Mar 04; Vol. 122 (9), pp. e2417308122. Date of Electronic Publication: 2025 Feb 24.
Publication Type: Journal Article
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
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  Data: RORγt-expressing dendritic cells are functionally versatile and evolutionarily conserved antigen-presenting cells.
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Institute of Clinical Neuroimmunology, University Hospital, Ludwig-Maximilians-Universität in Munich, Planegg-Martinsried 82152, Germany.; Biomedical Center, Medical Faculty, Ludwig-Maximilians-Universität in Munich, Planegg-Martinsried 82152, Germany.; Munich Cluster of Systems Neurology (SyNergy), Munich 81377, Germany.<br /><searchLink fieldCode="AU" term="%22de+la+Rosa+C%22">de la Rosa C</searchLink>; Institute of Clinical Neuroimmunology, University Hospital, Ludwig-Maximilians-Universität in Munich, Planegg-Martinsried 82152, Germany.; Biomedical Center, Medical Faculty, Ludwig-Maximilians-Universität in Munich, Planegg-Martinsried 82152, Germany.; Graduate School of Systemic Neurosciences, LMU, Planegg-Martinsried 82152, Germany.<br /><searchLink fieldCode="AU" term="%22Kuo+PY%22">Kuo PY</searchLink>; Institute for Immunology, Biomedical Center Munich, Faculty of Medicine, Ludwig-Maximilians-Universität in Munich, Planegg-Martinsried 82152, Germany.; Biomedical Center, Institute of Cardiovascular Physiology and Pathophysiology, Faculty of Medicine, Ludwig-Maximilians-Universität in Munich, Planegg-Martinsried 82152, Germany.<br /><searchLink fieldCode="AU" term="%22Altman+A%22">Altman A</searchLink>; 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