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HIV-1 Gag-protease-driven replicative capacity influences T-cell metabolism, cytokine induction, and viral cell-to-cell spread.

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Title: HIV-1 Gag-protease-driven replicative capacity influences T-cell metabolism, cytokine induction, and viral cell-to-cell spread.
Authors: Baiyegunhi OO; Africa Health Research Institute, Durban, South Africa.; HIV Pathogenesis Programme, The Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa., Mthembu K; Africa Health Research Institute, Durban, South Africa., Reuschl A-K; Division of Infection and Immunity, University College London, London, United Kingdom., Ojwach D; HIV Pathogenesis Programme, The Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa., Farinre O; HIV Pathogenesis Programme, The Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa., Maimela M; Africa Health Research Institute, Durban, South Africa., Balinda S; Medical Research Council, UVRI & LSTHM Uganda Research Unit, Entebbe, Uganda., Price M; Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California, USA.; IAVI, New York, New York, USA., Bunders MJ; Division of Regenerative Medicine and Immunology, III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Ragon Institute of MGH, MIT, and Harvard University, Boston, USA., Altfeld M; Research Department Virus Immunology, Leibniz Institute of Virology, Hamburg, Germany., Jolly C; Division of Infection and Immunity, University College London, London, United Kingdom., Mann J; HIV Pathogenesis Programme, The Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa., Ndung'u T; Africa Health Research Institute, Durban, South Africa.; HIV Pathogenesis Programme, The Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa.; Division of Infection and Immunity, University College London, London, United Kingdom.; Ragon Institute of MGH, MIT, and Harvard University, Boston, USA.
Source: MBio [mBio] 2025 Apr 09; Vol. 16 (4), pp. e0356524. Date of Electronic Publication: 2025 Feb 25.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 101519231 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2150-7511 (Electronic) NLM ISO Abbreviation: mBio Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Baiyegunhi+OO%22">Baiyegunhi OO</searchLink>; Africa Health Research Institute, Durban, South Africa.; HIV Pathogenesis Programme, The Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa.<br /><searchLink fieldCode="AU" term="%22Mthembu+K%22">Mthembu K</searchLink>; Africa Health Research Institute, Durban, South Africa.<br /><searchLink fieldCode="AU" term="%22Reuschl+A-K%22">Reuschl A-K</searchLink>; Division of Infection and Immunity, University College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Ojwach+D%22">Ojwach D</searchLink>; HIV Pathogenesis Programme, The Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa.<br /><searchLink fieldCode="AU" term="%22Farinre+O%22">Farinre O</searchLink>; HIV Pathogenesis Programme, The Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa.<br /><searchLink fieldCode="AU" term="%22Maimela+M%22">Maimela M</searchLink>; Africa Health Research Institute, Durban, South Africa.<br /><searchLink fieldCode="AU" term="%22Balinda+S%22">Balinda S</searchLink>; Medical Research Council, UVRI & LSTHM Uganda Research Unit, Entebbe, Uganda.<br /><searchLink fieldCode="AU" term="%22Price+M%22">Price M</searchLink>; Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California, USA.; IAVI, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Bunders+MJ%22">Bunders MJ</searchLink>; Division of Regenerative Medicine and Immunology, III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Ragon Institute of MGH, MIT, and Harvard University, Boston, USA.<br /><searchLink fieldCode="AU" term="%22Altfeld+M%22">Altfeld M</searchLink>; Research Department Virus Immunology, Leibniz Institute of Virology, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Jolly+C%22">Jolly C</searchLink>; Division of Infection and Immunity, University College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Mann+J%22">Mann J</searchLink>; HIV Pathogenesis Programme, The Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa.<br /><searchLink fieldCode="AU" term="%22Ndung'u+T%22">Ndung'u T</searchLink>; Africa Health Research Institute, Durban, South Africa.; HIV Pathogenesis Programme, The Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa.; Division of Infection and Immunity, University College London, London, United Kingdom.; Ragon Institute of MGH, MIT, and Harvard University, Boston, USA.
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  Data: <searchLink fieldCode="JN" term="%22101519231%22">MBio</searchLink> [mBio] 2025 Apr 09; Vol. 16 (4), pp. e0356524. <i>Date of Electronic Publication: </i>2025 Feb 25.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Society+for+Microbiology%22">American Society for Microbiology </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101519231 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2150-7511 (Electronic) <i>NLM ISO Abbreviation: </i>mBio <i>Subsets: </i>MEDLINE
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