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Immune monitoring of trabectedin therapy in refractory soft tissue sarcoma patients - the IMMUNYON study.

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Title: Immune monitoring of trabectedin therapy in refractory soft tissue sarcoma patients - the IMMUNYON study.
Authors: Rodrigues-Santos P; Laboratory of Immunology and Oncology, Center for Neurosciences and Cell Biology (CNC), University of Coimbra, Coimbra, Portugal.; Institute of Immunology, University of Coimbra, Faculty of Medicine (FMUC), Coimbra, Portugal.; Center for Investigation in Environment, Genetics and Oncobiology (CIMAGO), University of Coimbra, Coimbra, Portugal.; Coimbra Institute for Clinical and Biomedical Research (iCBR), University of Coimbra, Coimbra, Portugal.; Center for Innovation in Biomedicine and Biotechnology (CIBB), University of Coimbra, Coimbra, Portugal.; Clinical and Academic Centre of Coimbra (CACC), Coimbra, Portugal., Almeida JS; Laboratory of Immunology and Oncology, Center for Neurosciences and Cell Biology (CNC), University of Coimbra, Coimbra, Portugal.; Institute of Immunology, University of Coimbra, Faculty of Medicine (FMUC), Coimbra, Portugal.; Center for Investigation in Environment, Genetics and Oncobiology (CIMAGO), University of Coimbra, Coimbra, Portugal.; Coimbra Institute for Clinical and Biomedical Research (iCBR), University of Coimbra, Coimbra, Portugal.; Center for Innovation in Biomedicine and Biotechnology (CIBB), University of Coimbra, Coimbra, Portugal.; Clinical and Academic Centre of Coimbra (CACC), Coimbra, Portugal., Sousa LM; Laboratory of Immunology and Oncology, Center for Neurosciences and Cell Biology (CNC), University of Coimbra, Coimbra, Portugal.; Center for Innovation in Biomedicine and Biotechnology (CIBB), University of Coimbra, Coimbra, Portugal.; Clinical and Academic Centre of Coimbra (CACC), Coimbra, Portugal., Couceiro P; Laboratory of Immunology and Oncology, Center for Neurosciences and Cell Biology (CNC), University of Coimbra, Coimbra, Portugal.; Center for Investigation in Environment, Genetics and Oncobiology (CIMAGO), University of Coimbra, Coimbra, Portugal.; Coimbra Institute for Clinical and Biomedical Research (iCBR), University of Coimbra, Coimbra, Portugal.; Center for Innovation in Biomedicine and Biotechnology (CIBB), University of Coimbra, Coimbra, Portugal., Martinho A; Blood and Transplantation Center of Coimbra, Portuguese Institute for Blood and Transplantation (IPST), Coimbra, Portugal., Rodrigues J; Tumor Unit of the Locomotor Apparatus, University Clinic of Orthopedics, Orthopedics Oncology Service, Coimbra Local Health Unit (ULSC), Coimbra, Portugal., Fonseca R; Tumor Unit of the Locomotor Apparatus, University Clinic of Orthopedics, Orthopedics Oncology Service, Coimbra Local Health Unit (ULSC), Coimbra, Portugal., Santos-Rosa M; Institute of Immunology, University of Coimbra, Faculty of Medicine (FMUC), Coimbra, Portugal.; Center for Investigation in Environment, Genetics and Oncobiology (CIMAGO), University of Coimbra, Coimbra, Portugal.; Coimbra Institute for Clinical and Biomedical Research (iCBR), University of Coimbra, Coimbra, Portugal.; Center for Innovation in Biomedicine and Biotechnology (CIBB), University of Coimbra, Coimbra, Portugal.; Clinical and Academic Centre of Coimbra (CACC), Coimbra, Portugal., Freitas-Tavares P; Tumor Unit of the Locomotor Apparatus, University Clinic of Orthopedics, Orthopedics Oncology Service, Coimbra Local Health Unit (ULSC), Coimbra, Portugal., Casanova JM; Center for Investigation in Environment, Genetics and Oncobiology (CIMAGO), University of Coimbra, Coimbra, Portugal.; Coimbra Institute for Clinical and Biomedical Research (iCBR), University of Coimbra, Coimbra, Portugal.; Center for Innovation in Biomedicine and Biotechnology (CIBB), University of Coimbra, Coimbra, Portugal.; Clinical and Academic Centre of Coimbra (CACC), Coimbra, Portugal.; Tumor Unit of the Locomotor Apparatus, University Clinic of Orthopedics, Orthopedics Oncology Service, Coimbra Local Health Unit (ULSC), Coimbra, Portugal.
Source: Frontiers in immunology [Front Immunol] 2025 Feb 11; Vol. 16, pp. 1516793. Date of Electronic Publication: 2025 Feb 11 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Rodrigues-Santos+P%22">Rodrigues-Santos P</searchLink>; Laboratory of Immunology and Oncology, Center for Neurosciences and Cell Biology (CNC), University of Coimbra, Coimbra, Portugal.; Institute of Immunology, University of Coimbra, Faculty of Medicine (FMUC), Coimbra, Portugal.; Center for Investigation in Environment, Genetics and Oncobiology (CIMAGO), University of Coimbra, Coimbra, Portugal.; Coimbra Institute for Clinical and Biomedical Research (iCBR), University of Coimbra, Coimbra, Portugal.; Center for Innovation in Biomedicine and Biotechnology (CIBB), University of Coimbra, Coimbra, Portugal.; Clinical and Academic Centre of Coimbra (CACC), Coimbra, Portugal.<br /><searchLink fieldCode="AU" term="%22Almeida+JS%22">Almeida JS</searchLink>; Laboratory of Immunology and Oncology, Center for Neurosciences and Cell Biology (CNC), University of Coimbra, Coimbra, Portugal.; Institute of Immunology, University of Coimbra, Faculty of Medicine (FMUC), Coimbra, Portugal.; Center for Investigation in Environment, Genetics and Oncobiology (CIMAGO), University of Coimbra, Coimbra, Portugal.; Coimbra Institute for Clinical and Biomedical Research (iCBR), University of Coimbra, Coimbra, Portugal.; Center for Innovation in Biomedicine and Biotechnology (CIBB), University of Coimbra, Coimbra, Portugal.; Clinical and Academic Centre of Coimbra (CACC), Coimbra, Portugal.<br /><searchLink fieldCode="AU" term="%22Sousa+LM%22">Sousa LM</searchLink>; Laboratory of Immunology and Oncology, Center for Neurosciences and Cell Biology (CNC), University of Coimbra, Coimbra, Portugal.; Center for Innovation in Biomedicine and Biotechnology (CIBB), University of Coimbra, Coimbra, Portugal.; Clinical and Academic Centre of Coimbra (CACC), Coimbra, Portugal.<br /><searchLink fieldCode="AU" term="%22Couceiro+P%22">Couceiro P</searchLink>; Laboratory of Immunology and Oncology, Center for Neurosciences and Cell Biology (CNC), University of Coimbra, Coimbra, Portugal.; Center for Investigation in Environment, Genetics and Oncobiology (CIMAGO), University of Coimbra, Coimbra, Portugal.; Coimbra Institute for Clinical and Biomedical Research (iCBR), University of Coimbra, Coimbra, Portugal.; Center for Innovation in Biomedicine and Biotechnology (CIBB), University of Coimbra, Coimbra, Portugal.<br /><searchLink fieldCode="AU" term="%22Martinho+A%22">Martinho A</searchLink>; Blood and Transplantation Center of Coimbra, Portuguese Institute for Blood and Transplantation (IPST), Coimbra, Portugal.<br /><searchLink fieldCode="AU" term="%22Rodrigues+J%22">Rodrigues J</searchLink>; Tumor Unit of the Locomotor Apparatus, University Clinic of Orthopedics, Orthopedics Oncology Service, Coimbra Local Health Unit (ULSC), Coimbra, Portugal.<br /><searchLink fieldCode="AU" term="%22Fonseca+R%22">Fonseca R</searchLink>; Tumor Unit of the Locomotor Apparatus, University Clinic of Orthopedics, Orthopedics Oncology Service, Coimbra Local Health Unit (ULSC), Coimbra, Portugal.<br /><searchLink fieldCode="AU" term="%22Santos-Rosa+M%22">Santos-Rosa M</searchLink>; Institute of Immunology, University of Coimbra, Faculty of Medicine (FMUC), Coimbra, Portugal.; Center for Investigation in Environment, Genetics and Oncobiology (CIMAGO), University of Coimbra, Coimbra, Portugal.; Coimbra Institute for Clinical and Biomedical Research (iCBR), University of Coimbra, Coimbra, Portugal.; Center for Innovation in Biomedicine and Biotechnology (CIBB), University of Coimbra, Coimbra, Portugal.; Clinical and Academic Centre of Coimbra (CACC), Coimbra, Portugal.<br /><searchLink fieldCode="AU" term="%22Freitas-Tavares+P%22">Freitas-Tavares P</searchLink>; Tumor Unit of the Locomotor Apparatus, University Clinic of Orthopedics, Orthopedics Oncology Service, Coimbra Local Health Unit (ULSC), Coimbra, Portugal.<br /><searchLink fieldCode="AU" term="%22Casanova+JM%22">Casanova JM</searchLink>; Center for Investigation in Environment, Genetics and Oncobiology (CIMAGO), University of Coimbra, Coimbra, Portugal.; Coimbra Institute for Clinical and Biomedical Research (iCBR), University of Coimbra, Coimbra, Portugal.; Center for Innovation in Biomedicine and Biotechnology (CIBB), University of Coimbra, Coimbra, Portugal.; Clinical and Academic Centre of Coimbra (CACC), Coimbra, Portugal.; Tumor Unit of the Locomotor Apparatus, University Clinic of Orthopedics, Orthopedics Oncology Service, Coimbra Local Health Unit (ULSC), Coimbra, Portugal.
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