Design and synthesis of novel HDAC6 inhibitor dimer as HDAC6 degrader for cancer treatment by palladium catalysed dimerisation.
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| Title: | Design and synthesis of novel HDAC6 inhibitor dimer as HDAC6 degrader for cancer treatment by palladium catalysed dimerisation. |
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| Authors: | Lin C; School of Pharmacy, National Taiwan University, Taipei, ROC., Hsu JL; School of Pharmacy, National Taiwan University, Taipei, ROC.; Department of Nursing, Chang Gung University of Science and Technology, Taoyuan City, ROC.; Division of Hematology-Oncology, Department of Internal Medicine, Chang Gung Memorial Hospital, Linkou Medical Center, Taoyuan City, ROC., Hsu YT; School of Pharmacy, National Taiwan University, Taipei, ROC., Fan KC; School of Pharmacy, National Taiwan University, Taipei, ROC., Wu SS; School of Pharmacy, National Taiwan University, Taipei, ROC., Lin MH; Department and Graduate Institute of Medical Microbiology, College of Medicine, National Taiwan University, Taipei, ROC., Guh JH; School of Pharmacy, National Taiwan University, Taipei, ROC., Yu CW; School of Pharmacy, National Taiwan University, Taipei, ROC. |
| Source: | Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2025 Dec; Vol. 40 (1), pp. 2468355. Date of Electronic Publication: 2025 Feb 27. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Taylor & Francis Country of Publication: England NLM ID: 101150203 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1475-6374 (Electronic) Linking ISSN: 14756366 NLM ISO Abbreviation: J Enzyme Inhib Med Chem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1475-6374 |
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| DOI: | 10.1080/14756366.2025.2468355 |
