Regulatory T cells constrain T cells of shared specificity to enforce tolerance during infection. - Klawon DEJ; Pagane N; Walker MT; Ganci NK; Miller CH; Gai E; Rodriguez DM; Ryan-Payseur BK; Duncombe RK; Adams EJ; Maienschein-Cline M; Freitag NE; et al. (Science (New York, N.Y.), 2025)