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Targeting osteoclasts for treatment of high-risk B-cell acute lymphoblastic leukemia.

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Title: Targeting osteoclasts for treatment of high-risk B-cell acute lymphoblastic leukemia.
Authors: Kotecha RS; Leukaemia Translational Research Laboratory, WA Kids Cancer Centre, The Kids Research Institute Australia, Perth, WA, Australia.; Curtin Medical School, Curtin University, Perth, WA, Australia.; Department of Clinical Haematology, Oncology, Blood and Marrow Transplantation, Perth Children's Hospital, Perth, WA, Australia.; Medical School, University of Western Australia, Perth, WA, Australia., Trinder SM; Department of Clinical Haematology, Oncology, Blood and Marrow Transplantation, Perth Children's Hospital, Perth, WA, Australia., Hughes AM; Leukaemia Translational Research Laboratory, WA Kids Cancer Centre, The Kids Research Institute Australia, Perth, WA, Australia.; Curtin Medical School, Curtin University, Perth, WA, Australia., Mullin BH; School of Biomedical Sciences, University of Western Australia, Perth, WA, Australia.; Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Perth, WA, Australia., Rashid S; School of Biomedical Sciences, University of Western Australia, Perth, WA, Australia., Yuan J; School of Biomedical Sciences, University of Western Australia, Perth, WA, Australia., Xu J; School of Biomedical Sciences, University of Western Australia, Perth, WA, Australia.; Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China., Duncan O; Centre for Microscopy, Characterisation and Analysis, University of Western Australia, Perth, WA, Australia., Skut P; Leukaemia Translational Research Laboratory, WA Kids Cancer Centre, The Kids Research Institute Australia, Perth, WA, Australia., Chua GA; Leukaemia Translational Research Laboratory, WA Kids Cancer Centre, The Kids Research Institute Australia, Perth, WA, Australia., Singh S; Leukaemia Translational Research Laboratory, WA Kids Cancer Centre, The Kids Research Institute Australia, Perth, WA, Australia., Oommen J; Leukaemia Translational Research Laboratory, WA Kids Cancer Centre, The Kids Research Institute Australia, Perth, WA, Australia., Lock RB; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia.; School of Clinical Medicine, UNSW Medicine & Health, University of New South Wales, Sydney, NSW, Australia.; UNSW Centre for Childhood Cancer Research, University of New South Wales, Sydney, NSW, Australia., Kees UR; Leukaemia Translational Research Laboratory, WA Kids Cancer Centre, The Kids Research Institute Australia, Perth, WA, Australia.; Medical School, University of Western Australia, Perth, WA, Australia., Malinge S; Leukaemia Translational Research Laboratory, WA Kids Cancer Centre, The Kids Research Institute Australia, Perth, WA, Australia., Kuek V; Leukaemia Translational Research Laboratory, WA Kids Cancer Centre, The Kids Research Institute Australia, Perth, WA, Australia.; Curtin Medical School, Curtin University, Perth, WA, Australia.; School of Biomedical Sciences, University of Western Australia, Perth, WA, Australia., Cheung LC; Leukaemia Translational Research Laboratory, WA Kids Cancer Centre, The Kids Research Institute Australia, Perth, WA, Australia. l.cheung@curtin.edu.au.; Curtin Medical School, Curtin University, Perth, WA, Australia. l.cheung@curtin.edu.au.; Curtin Medical Research Institute, Curtin University, Perth, WA, Australia. l.cheung@curtin.edu.au.
Source: Blood cancer journal [Blood Cancer J] 2025 Feb 27; Vol. 15 (1), pp. 25. Date of Electronic Publication: 2025 Feb 27.
Publication Type: Letter
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101568469 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-5385 (Electronic) Linking ISSN: 20445385 NLM ISO Abbreviation: Blood Cancer J Subsets: MEDLINE; In Process
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  Data: Targeting osteoclasts for treatment of high-risk B-cell acute lymphoblastic leukemia.
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  Data: <searchLink fieldCode="AU" term="%22Kotecha+RS%22">Kotecha RS</searchLink>; Leukaemia Translational Research Laboratory, WA Kids Cancer Centre, The Kids Research Institute Australia, Perth, WA, Australia.; Curtin Medical School, Curtin University, Perth, WA, Australia.; Department of Clinical Haematology, Oncology, Blood and Marrow Transplantation, Perth Children's Hospital, Perth, WA, Australia.; Medical School, University of Western Australia, Perth, WA, Australia.<br /><searchLink fieldCode="AU" term="%22Trinder+SM%22">Trinder SM</searchLink>; Department of Clinical Haematology, Oncology, Blood and Marrow Transplantation, Perth Children's Hospital, Perth, WA, Australia.<br /><searchLink fieldCode="AU" term="%22Hughes+AM%22">Hughes AM</searchLink>; Leukaemia Translational Research Laboratory, WA Kids Cancer Centre, The Kids Research Institute Australia, Perth, WA, Australia.; Curtin Medical School, Curtin University, Perth, WA, Australia.<br /><searchLink fieldCode="AU" term="%22Mullin+BH%22">Mullin BH</searchLink>; School of Biomedical Sciences, University of Western Australia, Perth, WA, Australia.; Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Perth, WA, Australia.<br /><searchLink fieldCode="AU" term="%22Rashid+S%22">Rashid S</searchLink>; School of Biomedical Sciences, University of Western Australia, Perth, WA, Australia.<br /><searchLink fieldCode="AU" term="%22Yuan+J%22">Yuan J</searchLink>; School of Biomedical Sciences, University of Western Australia, Perth, WA, Australia.<br /><searchLink fieldCode="AU" term="%22Xu+J%22">Xu J</searchLink>; School of Biomedical Sciences, University of Western Australia, Perth, WA, Australia.; Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.<br /><searchLink fieldCode="AU" term="%22Duncan+O%22">Duncan O</searchLink>; Centre for Microscopy, Characterisation and Analysis, University of Western Australia, Perth, WA, Australia.<br /><searchLink fieldCode="AU" term="%22Skut+P%22">Skut P</searchLink>; Leukaemia Translational Research Laboratory, WA Kids Cancer Centre, The Kids Research Institute Australia, Perth, WA, Australia.<br /><searchLink fieldCode="AU" term="%22Chua+GA%22">Chua GA</searchLink>; Leukaemia Translational Research Laboratory, WA Kids Cancer Centre, The Kids Research Institute Australia, Perth, WA, Australia.<br /><searchLink fieldCode="AU" term="%22Singh+S%22">Singh S</searchLink>; Leukaemia Translational Research Laboratory, WA Kids Cancer Centre, The Kids Research Institute Australia, Perth, WA, Australia.<br /><searchLink fieldCode="AU" term="%22Oommen+J%22">Oommen J</searchLink>; Leukaemia Translational Research Laboratory, WA Kids Cancer Centre, The Kids Research Institute Australia, Perth, WA, Australia.<br /><searchLink fieldCode="AU" term="%22Lock+RB%22">Lock RB</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia.; School of Clinical Medicine, UNSW Medicine & Health, University of New South Wales, Sydney, NSW, Australia.; UNSW Centre for Childhood Cancer Research, University of New South Wales, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Kees+UR%22">Kees UR</searchLink>; Leukaemia Translational Research Laboratory, WA Kids Cancer Centre, The Kids Research Institute Australia, Perth, WA, Australia.; Medical School, University of Western Australia, Perth, WA, Australia.<br /><searchLink fieldCode="AU" term="%22Malinge+S%22">Malinge S</searchLink>; Leukaemia Translational Research Laboratory, WA Kids Cancer Centre, The Kids Research Institute Australia, Perth, WA, Australia.<br /><searchLink fieldCode="AU" term="%22Kuek+V%22">Kuek V</searchLink>; Leukaemia Translational Research Laboratory, WA Kids Cancer Centre, The Kids Research Institute Australia, Perth, WA, Australia.; Curtin Medical School, Curtin University, Perth, WA, Australia.; School of Biomedical Sciences, University of Western Australia, Perth, WA, Australia.<br /><searchLink fieldCode="AU" term="%22Cheung+LC%22">Cheung LC</searchLink>; Leukaemia Translational Research Laboratory, WA Kids Cancer Centre, The Kids Research Institute Australia, Perth, WA, Australia. l.cheung@curtin.edu.au.; Curtin Medical School, Curtin University, Perth, WA, Australia. l.cheung@curtin.edu.au.; Curtin Medical Research Institute, Curtin University, Perth, WA, Australia. l.cheung@curtin.edu.au.
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  Data: <searchLink fieldCode="JN" term="%22101568469%22">Blood cancer journal</searchLink> [Blood Cancer J] 2025 Feb 27; Vol. 15 (1), pp. 25. <i>Date of Electronic Publication: </i>2025 Feb 27.
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