View in EDS HTML Full Text PDF Full Text

Maintenance of p-eIF2α levels by the eIF2B complex is vital for colorectal cancer.

Saved in:
Bibliographic Details
Title: Maintenance of p-eIF2α levels by the eIF2B complex is vital for colorectal cancer.
Authors: Škapik IP; Theodor Boveri Institute, Biocenter, University of Würzburg, 97074, Würzburg, Germany.; Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital Würzburg, 97080, Würzburg, Germany.; Goethe University Frankfurt, University Hospital, Department of General, Visceral, Transplant and Thoracic Surgery, Frankfurt am Main, Germany., Giacomelli C; CRUK Scotland Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK., Hahn S; Theodor Boveri Institute, Biocenter, University of Würzburg, 97074, Würzburg, Germany.; Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital Würzburg, 97080, Würzburg, Germany.; Goethe University Frankfurt, University Hospital, Department of General, Visceral, Transplant and Thoracic Surgery, Frankfurt am Main, Germany., Deinlein H; Theodor Boveri Institute, Biocenter, University of Würzburg, 97074, Würzburg, Germany.; Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital Würzburg, 97080, Würzburg, Germany., Gallant P; Theodor Boveri Institute, Biocenter, University of Würzburg, 97074, Würzburg, Germany., Diebold M; Theodor Boveri Institute, Biocenter, University of Würzburg, 97074, Würzburg, Germany.; Institute of Pharmacy and Food Chemistry, University of Würzburg, 97074, Würzburg, Germany., Biayna J; Theodor Boveri Institute, Biocenter, University of Würzburg, 97074, Würzburg, Germany.; Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital Würzburg, 97080, Würzburg, Germany.; Institute of Cardiovascular Regeneration, Centre for Molecular Medicine, Goethe University Frankfurt, 60590, Frankfurt am Main, Germany., Hendricks A; Theodor Boveri Institute, Biocenter, University of Würzburg, 97074, Würzburg, Germany.; Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital Würzburg, 97080, Würzburg, Germany., Olimski L; Theodor Boveri Institute, Biocenter, University of Würzburg, 97074, Würzburg, Germany.; Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital Würzburg, 97080, Würzburg, Germany., Otto C; Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital Würzburg, 97080, Würzburg, Germany., Kastner C; Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital Würzburg, 97080, Würzburg, Germany., Wolf E; Theodor Boveri Institute, Biocenter, University of Würzburg, 97074, Würzburg, Germany.; Institute of Biochemistry, CAU Kiel, 24118, Kiel, Germany., Schülein-Völk C; Theodor Boveri Institute, Biocenter, University of Würzburg, 97074, Würzburg, Germany., Maurus K; Institute of Pathology, University of Würzburg, 97074, Würzburg, Germany., Rosenwald A; Institute of Pathology, University of Würzburg, 97074, Würzburg, Germany., Schleussner N; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), Heidelberg, Germany.; Department of General, Visceral and Transplantation Surgery, University Hospital Heidelberg, University Heidelberg, 69120, Heidelberg, Germany.; Cancer Progression and Metastasis Group, German Cancer Research Center (DKFZ) and DKFZ-ZMBH Alliance, Heidelberg, Germany.; German Cancer Consortium (DKTK), DKFZ, Core Center Heidelberg, Heidelberg, Germany., Jackstadt RF; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), Heidelberg, Germany.; Cancer Progression and Metastasis Group, German Cancer Research Center (DKFZ) and DKFZ-ZMBH Alliance, Heidelberg, Germany.; German Cancer Consortium (DKTK), DKFZ, Core Center Heidelberg, Heidelberg, Germany., Schlegel N; Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital Würzburg, 97080, Würzburg, Germany., Germer CT; Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital Würzburg, 97080, Würzburg, Germany.; Comprehensive Cancer Center Mainfranken, University Hospital Würzburg, 97080, Würzburg, Germany., Bushell M; CRUK Scotland Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK.; School of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, G61 1QH, UK., Eilers M; Theodor Boveri Institute, Biocenter, University of Würzburg, 97074, Würzburg, Germany.; Comprehensive Cancer Center Mainfranken, University Hospital Würzburg, 97080, Würzburg, Germany., Schmidt S; Theodor Boveri Institute, Biocenter, University of Würzburg, 97074, Würzburg, Germany. schmidt_s12@ukw.de.; Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital Würzburg, 97080, Würzburg, Germany. schmidt_s12@ukw.de., Wiegering A; Theodor Boveri Institute, Biocenter, University of Würzburg, 97074, Würzburg, Germany. wiegering_a@ukw.de.; Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital Würzburg, 97080, Würzburg, Germany. wiegering_a@ukw.de.; Goethe University Frankfurt, University Hospital, Department of General, Visceral, Transplant and Thoracic Surgery, Frankfurt am Main, Germany. wiegering_a@ukw.de.; Comprehensive Cancer Center Mainfranken, University Hospital Würzburg, 97080, Würzburg, Germany. wiegering_a@ukw.de.
Source: The EMBO journal [EMBO J] 2025 Apr; Vol. 44 (7), pp. 2075-2105. Date of Electronic Publication: 2025 Feb 27.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE
Database: MEDLINE Ultimate
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 40016419
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Maintenance of p-eIF2α levels by the eIF2B complex is vital for colorectal cancer.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Škapik+IP%22">Škapik IP</searchLink>; Theodor Boveri Institute, Biocenter, University of Würzburg, 97074, Würzburg, Germany.; Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital Würzburg, 97080, Würzburg, Germany.; Goethe University Frankfurt, University Hospital, Department of General, Visceral, Transplant and Thoracic Surgery, Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Giacomelli+C%22">Giacomelli C</searchLink>; CRUK Scotland Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK.<br /><searchLink fieldCode="AU" term="%22Hahn+S%22">Hahn S</searchLink>; Theodor Boveri Institute, Biocenter, University of Würzburg, 97074, Würzburg, Germany.; Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital Würzburg, 97080, Würzburg, Germany.; Goethe University Frankfurt, University Hospital, Department of General, Visceral, Transplant and Thoracic Surgery, Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Deinlein+H%22">Deinlein H</searchLink>; Theodor Boveri Institute, Biocenter, University of Würzburg, 97074, Würzburg, Germany.; Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital Würzburg, 97080, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Gallant+P%22">Gallant P</searchLink>; Theodor Boveri Institute, Biocenter, University of Würzburg, 97074, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Diebold+M%22">Diebold M</searchLink>; Theodor Boveri Institute, Biocenter, University of Würzburg, 97074, Würzburg, Germany.; Institute of Pharmacy and Food Chemistry, University of Würzburg, 97074, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Biayna+J%22">Biayna J</searchLink>; Theodor Boveri Institute, Biocenter, University of Würzburg, 97074, Würzburg, Germany.; Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital Würzburg, 97080, Würzburg, Germany.; Institute of Cardiovascular Regeneration, Centre for Molecular Medicine, Goethe University Frankfurt, 60590, Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Hendricks+A%22">Hendricks A</searchLink>; Theodor Boveri Institute, Biocenter, University of Würzburg, 97074, Würzburg, Germany.; Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital Würzburg, 97080, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Olimski+L%22">Olimski L</searchLink>; Theodor Boveri Institute, Biocenter, University of Würzburg, 97074, Würzburg, Germany.; Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital Würzburg, 97080, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Otto+C%22">Otto C</searchLink>; Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital Würzburg, 97080, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Kastner+C%22">Kastner C</searchLink>; Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital Würzburg, 97080, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Wolf+E%22">Wolf E</searchLink>; Theodor Boveri Institute, Biocenter, University of Würzburg, 97074, Würzburg, Germany.; Institute of Biochemistry, CAU Kiel, 24118, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Schülein-Völk+C%22">Schülein-Völk C</searchLink>; Theodor Boveri Institute, Biocenter, University of Würzburg, 97074, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Maurus+K%22">Maurus K</searchLink>; Institute of Pathology, University of Würzburg, 97074, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Rosenwald+A%22">Rosenwald A</searchLink>; Institute of Pathology, University of Würzburg, 97074, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Schleussner+N%22">Schleussner N</searchLink>; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), Heidelberg, Germany.; Department of General, Visceral and Transplantation Surgery, University Hospital Heidelberg, University Heidelberg, 69120, Heidelberg, Germany.; Cancer Progression and Metastasis Group, German Cancer Research Center (DKFZ) and DKFZ-ZMBH Alliance, Heidelberg, Germany.; German Cancer Consortium (DKTK), DKFZ, Core Center Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Jackstadt+RF%22">Jackstadt RF</searchLink>; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), Heidelberg, Germany.; Cancer Progression and Metastasis Group, German Cancer Research Center (DKFZ) and DKFZ-ZMBH Alliance, Heidelberg, Germany.; German Cancer Consortium (DKTK), DKFZ, Core Center Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Schlegel+N%22">Schlegel N</searchLink>; Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital Würzburg, 97080, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Germer+CT%22">Germer CT</searchLink>; Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital Würzburg, 97080, Würzburg, Germany.; Comprehensive Cancer Center Mainfranken, University Hospital Würzburg, 97080, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Bushell+M%22">Bushell M</searchLink>; CRUK Scotland Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK.; School of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, G61 1QH, UK.<br /><searchLink fieldCode="AU" term="%22Eilers+M%22">Eilers M</searchLink>; Theodor Boveri Institute, Biocenter, University of Würzburg, 97074, Würzburg, Germany.; Comprehensive Cancer Center Mainfranken, University Hospital Würzburg, 97080, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Schmidt+S%22">Schmidt S</searchLink>; Theodor Boveri Institute, Biocenter, University of Würzburg, 97074, Würzburg, Germany. schmidt_s12@ukw.de.; Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital Würzburg, 97080, Würzburg, Germany. schmidt_s12@ukw.de.<br /><searchLink fieldCode="AU" term="%22Wiegering+A%22">Wiegering A</searchLink>; Theodor Boveri Institute, Biocenter, University of Würzburg, 97074, Würzburg, Germany. wiegering_a@ukw.de.; Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital Würzburg, 97080, Würzburg, Germany. wiegering_a@ukw.de.; Goethe University Frankfurt, University Hospital, Department of General, Visceral, Transplant and Thoracic Surgery, Frankfurt am Main, Germany. wiegering_a@ukw.de.; Comprehensive Cancer Center Mainfranken, University Hospital Würzburg, 97080, Würzburg, Germany. wiegering_a@ukw.de.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%228208664%22">The EMBO journal</searchLink> [EMBO J] 2025 Apr; Vol. 44 (7), pp. 2075-2105. <i>Date of Electronic Publication: </i>2025 Feb 27.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>8208664 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1460-2075 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2202614189%22">02614189 </searchLink><i>NLM ISO Abbreviation: </i>EMBO J <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40016419
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1038/s44318-025-00381-9
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 2075
    Titles:
      – TitleFull: Maintenance of p-eIF2α levels by the eIF2B complex is vital for colorectal cancer.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Škapik IP
      – PersonEntity:
          Name:
            NameFull: Giacomelli C
      – PersonEntity:
          Name:
            NameFull: Hahn S
      – PersonEntity:
          Name:
            NameFull: Deinlein H
      – PersonEntity:
          Name:
            NameFull: Gallant P
      – PersonEntity:
          Name:
            NameFull: Diebold M
      – PersonEntity:
          Name:
            NameFull: Biayna J
      – PersonEntity:
          Name:
            NameFull: Hendricks A
      – PersonEntity:
          Name:
            NameFull: Olimski L
      – PersonEntity:
          Name:
            NameFull: Otto C
      – PersonEntity:
          Name:
            NameFull: Kastner C
      – PersonEntity:
          Name:
            NameFull: Wolf E
      – PersonEntity:
          Name:
            NameFull: Schülein-Völk C
      – PersonEntity:
          Name:
            NameFull: Maurus K
      – PersonEntity:
          Name:
            NameFull: Rosenwald A
      – PersonEntity:
          Name:
            NameFull: Schleussner N
      – PersonEntity:
          Name:
            NameFull: Jackstadt RF
      – PersonEntity:
          Name:
            NameFull: Schlegel N
      – PersonEntity:
          Name:
            NameFull: Germer CT
      – PersonEntity:
          Name:
            NameFull: Bushell M
      – PersonEntity:
          Name:
            NameFull: Eilers M
      – PersonEntity:
          Name:
            NameFull: Schmidt S
      – PersonEntity:
          Name:
            NameFull: Wiegering A
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 04
              Text: 2025 Apr
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 1460-2075
          Numbering:
            – Type: volume
              Value: 44
            – Type: issue
              Value: 7
          Titles:
            – TitleFull: The EMBO journal
              Type: main
ResultId 1