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Platelet-derived extracellular vesicle drug delivery system loaded with kaempferol for treating corneal neovascularization.

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Title: Platelet-derived extracellular vesicle drug delivery system loaded with kaempferol for treating corneal neovascularization.
Authors: Liu GS; Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, East Melbourne, Australia; Graduate Institute of Biomedical Materials and Tissue Engineering, College of Biomedical Engineering, Taipei Medical University, Shuang-Ho Campus, New Taipei City, Taiwan; Ophthalmology, Department of Surgery, University of Melbourne, East Melbourne, Australia; Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia., Chen HA; Graduate Institute of Biomedical Materials and Tissue Engineering, College of Biomedical Engineering, Taipei Medical University, Shuang-Ho Campus, New Taipei City, Taiwan., Chang CY; Graduate Institute of Biomedical Materials and Tissue Engineering, College of Biomedical Engineering, Taipei Medical University, Shuang-Ho Campus, New Taipei City, Taiwan., Chen YJ; Graduate Institute of Biomedical Materials and Tissue Engineering, College of Biomedical Engineering, Taipei Medical University, Shuang-Ho Campus, New Taipei City, Taiwan; Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan., Wu YY; Graduate Institute of Biomedical Materials and Tissue Engineering, College of Biomedical Engineering, Taipei Medical University, Shuang-Ho Campus, New Taipei City, Taiwan., Widhibrata A; Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, East Melbourne, Australia., Yang YH; Graduate Institute of Biomedical Materials and Tissue Engineering, College of Biomedical Engineering, Taipei Medical University, Shuang-Ho Campus, New Taipei City, Taiwan., Hsieh EH; Graduate Institute of Biomedical Materials and Tissue Engineering, College of Biomedical Engineering, Taipei Medical University, Shuang-Ho Campus, New Taipei City, Taiwan., Delila L; Graduate Institute of Biomedical Materials and Tissue Engineering, College of Biomedical Engineering, Taipei Medical University, Shuang-Ho Campus, New Taipei City, Taiwan., Lin IC; Department of Ophthalmology, Wan Fang Hospital, Taipei Medical University, Taipei City, Taiwan; Department of Ophthalmology, School of Medicine, College of Medicine, Taipei Medical University, Taipei City, Taiwan., Burnouf T; Graduate Institute of Biomedical Materials and Tissue Engineering, College of Biomedical Engineering, Taipei Medical University, Shuang-Ho Campus, New Taipei City, Taiwan; International Ph. D. Program in Biomedical Engineering, College of Biomedical Engineering, Taipei Medical University, Shuang-Ho Campus, New Taipei City, Taiwan; Research Center of Biomedical Device, College of Biomedical Engineering, Taipei Medical University, Taipei City, Taiwan; International Ph. D. Program in Cell Therapy and Regenerative Medicine, College of Medicine, Taipei Medical University, Taipei City, Taiwan. Electronic address: thierry@tmu.edu.tw., Tseng CL; Graduate Institute of Biomedical Materials and Tissue Engineering, College of Biomedical Engineering, Taipei Medical University, Shuang-Ho Campus, New Taipei City, Taiwan; International Ph. D. Program in Biomedical Engineering, College of Biomedical Engineering, Taipei Medical University, Shuang-Ho Campus, New Taipei City, Taiwan; Research Center of Biomedical Device, College of Biomedical Engineering, Taipei Medical University, Taipei City, Taiwan; International Ph. D. Program in Cell Therapy and Regenerative Medicine, College of Medicine, Taipei Medical University, Taipei City, Taiwan. Electronic address: chingli@tmu.edu.tw.
Source: Biomaterials [Biomaterials] 2025 Aug; Vol. 319, pp. 123205. Date of Electronic Publication: 2025 Feb 24.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 8100316 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-5905 (Electronic) Linking ISSN: 01429612 NLM ISO Abbreviation: Biomaterials Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Liu+GS%22">Liu GS</searchLink>; Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, East Melbourne, Australia; Graduate Institute of Biomedical Materials and Tissue Engineering, College of Biomedical Engineering, Taipei Medical University, Shuang-Ho Campus, New Taipei City, Taiwan; Ophthalmology, Department of Surgery, University of Melbourne, East Melbourne, Australia; Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia.<br /><searchLink fieldCode="AU" term="%22Chen+HA%22">Chen HA</searchLink>; Graduate Institute of Biomedical Materials and Tissue Engineering, College of Biomedical Engineering, Taipei Medical University, Shuang-Ho Campus, New Taipei City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chang+CY%22">Chang CY</searchLink>; Graduate Institute of Biomedical Materials and Tissue Engineering, College of Biomedical Engineering, Taipei Medical University, Shuang-Ho Campus, New Taipei City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+YJ%22">Chen YJ</searchLink>; Graduate Institute of Biomedical Materials and Tissue Engineering, College of Biomedical Engineering, Taipei Medical University, Shuang-Ho Campus, New Taipei City, Taiwan; Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wu+YY%22">Wu YY</searchLink>; Graduate Institute of Biomedical Materials and Tissue Engineering, College of Biomedical Engineering, Taipei Medical University, Shuang-Ho Campus, New Taipei City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Widhibrata+A%22">Widhibrata A</searchLink>; Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, East Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Yang+YH%22">Yang YH</searchLink>; Graduate Institute of Biomedical Materials and Tissue Engineering, College of Biomedical Engineering, Taipei Medical University, Shuang-Ho Campus, New Taipei City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Hsieh+EH%22">Hsieh EH</searchLink>; Graduate Institute of Biomedical Materials and Tissue Engineering, College of Biomedical Engineering, Taipei Medical University, Shuang-Ho Campus, New Taipei City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Delila+L%22">Delila L</searchLink>; Graduate Institute of Biomedical Materials and Tissue Engineering, College of Biomedical Engineering, Taipei Medical University, Shuang-Ho Campus, New Taipei City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+IC%22">Lin IC</searchLink>; Department of Ophthalmology, Wan Fang Hospital, Taipei Medical University, Taipei City, Taiwan; Department of Ophthalmology, School of Medicine, College of Medicine, Taipei Medical University, Taipei City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Burnouf+T%22">Burnouf T</searchLink>; Graduate Institute of Biomedical Materials and Tissue Engineering, College of Biomedical Engineering, Taipei Medical University, Shuang-Ho Campus, New Taipei City, Taiwan; International Ph. D. Program in Biomedical Engineering, College of Biomedical Engineering, Taipei Medical University, Shuang-Ho Campus, New Taipei City, Taiwan; Research Center of Biomedical Device, College of Biomedical Engineering, Taipei Medical University, Taipei City, Taiwan; International Ph. D. Program in Cell Therapy and Regenerative Medicine, College of Medicine, Taipei Medical University, Taipei City, Taiwan. Electronic address: thierry@tmu.edu.tw.<br /><searchLink fieldCode="AU" term="%22Tseng+CL%22">Tseng CL</searchLink>; Graduate Institute of Biomedical Materials and Tissue Engineering, College of Biomedical Engineering, Taipei Medical University, Shuang-Ho Campus, New Taipei City, Taiwan; International Ph. D. Program in Biomedical Engineering, College of Biomedical Engineering, Taipei Medical University, Shuang-Ho Campus, New Taipei City, Taiwan; Research Center of Biomedical Device, College of Biomedical Engineering, Taipei Medical University, Taipei City, Taiwan; International Ph. D. Program in Cell Therapy and Regenerative Medicine, College of Medicine, Taipei Medical University, Taipei City, Taiwan. Electronic address: chingli@tmu.edu.tw.
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              Text: 2025 Aug
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