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The immunometabolic topography of tuberculosis granulomas governs cellular organization and bacterial control.

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Title: The immunometabolic topography of tuberculosis granulomas governs cellular organization and bacterial control.
Authors: McCaffrey EF; Department of Pathology, Stanford University School of Medicine, Stanford, CA.; Spatial Immunology Unit, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, MD., Delmastro AC; Department of Pathology, Stanford University School of Medicine, Stanford, CA., Fitzhugh I; The Department of Biomedical Sciences and Technology, AdventHealth University, Orlando, FL., Ranek JS; Department of Pathology, Stanford University School of Medicine, Stanford, CA., Douglas S; Department of Pathology, Stanford University School of Medicine, Stanford, CA., Peters JM; Department of Biological Engineering, MIT, Cambridge, MA.; Ragon Institute of Mass General, Harvard, and MIT, Cambridge, MA., Fullaway CC; Department of Pathology, Stanford University School of Medicine, Stanford, CA., Bosse M; Department of Pathology, Stanford University School of Medicine, Stanford, CA., Liu CC; Department of Pathology, Stanford University School of Medicine, Stanford, CA., Gillen C; The Department of Biomedical Sciences and Technology, AdventHealth University, Orlando, FL., Greenwald NF; Department of Pathology, Stanford University School of Medicine, Stanford, CA., Anzick S; Research Technologies Branch, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, NIH, Hamilton, MT., Martens C; Research Technologies Branch, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, NIH, Hamilton, MT., Winfree S; Research Technologies Branch, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, NIH, Hamilton, MT., Bai Y; Department of Pathology, Stanford University School of Medicine, Stanford, CA., Sowers C; Department of Pathology, Stanford University School of Medicine, Stanford, CA., Goldston M; Department of Pathology, Stanford University School of Medicine, Stanford, CA., Kong A; Department of Pathology, Stanford University School of Medicine, Stanford, CA., Boonrat P; Department of Pathology, Stanford University School of Medicine, Stanford, CA., Bigbee CL; Department of Microbiology and Molecular Genetics, School of Medicine, University of Pittsburgh, Pittsburgh, PA., Venugopalan R; Center for Vaccine Research, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15261.; Department of Infectious Diseases and Microbiology, University of Pittsburgh School of Public Health, Pittsburgh, PA., Maiello P; Department of Microbiology and Molecular Genetics, School of Medicine, University of Pittsburgh, Pittsburgh, PA.; Center for Vaccine Research, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15261., Klein E; Division of Laboratory Animal Research, University of Pittsburgh, Pittsburgh, PA, USA., Rodgers MA; Department of Microbiology and Molecular Genetics, School of Medicine, University of Pittsburgh, Pittsburgh, PA.; Center for Vaccine Research, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15261., Scanga CA; Department of Microbiology and Molecular Genetics, School of Medicine, University of Pittsburgh, Pittsburgh, PA.; Center for Vaccine Research, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15261., Lin PL; Center for Vaccine Research, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15261.; Department of Pediatrics, Division of Infectious Disease, Children's Hospital of Pittsburgh of the University of Pittsburgh Medical Center, Pittsburgh, PA., Kirschner D; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI., Fortune S; Ragon Institute of Mass General, Harvard, and MIT, Cambridge, MA.; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA., Bryson BD; Department of Biological Engineering, MIT, Cambridge, MA.; Ragon Institute of Mass General, Harvard, and MIT, Cambridge, MA., Butler JR; The Department of Biomedical Sciences and Technology, AdventHealth University, Orlando, FL., Mattila JT; Center for Vaccine Research, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15261.; Department of Infectious Diseases and Microbiology, University of Pittsburgh School of Public Health, Pittsburgh, PA., Flynn JL; Department of Microbiology and Molecular Genetics, School of Medicine, University of Pittsburgh, Pittsburgh, PA.; Center for Vaccine Research, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15261., Angelo M; Department of Pathology, Stanford University School of Medicine, Stanford, CA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Feb 23. Date of Electronic Publication: 2025 Feb 23.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: The immunometabolic topography of tuberculosis granulomas governs cellular organization and bacterial control.
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  Data: <searchLink fieldCode="AU" term="%22McCaffrey+EF%22">McCaffrey EF</searchLink>; Department of Pathology, Stanford University School of Medicine, Stanford, CA.; Spatial Immunology Unit, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, MD.<br /><searchLink fieldCode="AU" term="%22Delmastro+AC%22">Delmastro AC</searchLink>; Department of Pathology, Stanford University School of Medicine, Stanford, CA.<br /><searchLink fieldCode="AU" term="%22Fitzhugh+I%22">Fitzhugh I</searchLink>; The Department of Biomedical Sciences and Technology, AdventHealth University, Orlando, FL.<br /><searchLink fieldCode="AU" term="%22Ranek+JS%22">Ranek JS</searchLink>; Department of Pathology, Stanford University School of Medicine, Stanford, CA.<br /><searchLink fieldCode="AU" term="%22Douglas+S%22">Douglas S</searchLink>; Department of Pathology, Stanford University School of Medicine, Stanford, CA.<br /><searchLink fieldCode="AU" term="%22Peters+JM%22">Peters JM</searchLink>; Department of Biological Engineering, MIT, Cambridge, MA.; Ragon Institute of Mass General, Harvard, and MIT, Cambridge, MA.<br /><searchLink fieldCode="AU" term="%22Fullaway+CC%22">Fullaway CC</searchLink>; Department of Pathology, Stanford University School of Medicine, Stanford, CA.<br /><searchLink fieldCode="AU" term="%22Bosse+M%22">Bosse M</searchLink>; Department of Pathology, Stanford University School of Medicine, Stanford, CA.<br /><searchLink fieldCode="AU" term="%22Liu+CC%22">Liu CC</searchLink>; Department of Pathology, Stanford University School of Medicine, Stanford, CA.<br /><searchLink fieldCode="AU" term="%22Gillen+C%22">Gillen C</searchLink>; The Department of Biomedical Sciences and Technology, AdventHealth University, Orlando, FL.<br /><searchLink fieldCode="AU" term="%22Greenwald+NF%22">Greenwald NF</searchLink>; Department of Pathology, Stanford University School of Medicine, Stanford, CA.<br /><searchLink fieldCode="AU" term="%22Anzick+S%22">Anzick S</searchLink>; 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Department of Pathology, Stanford University School of Medicine, Stanford, CA.<br /><searchLink fieldCode="AU" term="%22Boonrat+P%22">Boonrat P</searchLink>; Department of Pathology, Stanford University School of Medicine, Stanford, CA.<br /><searchLink fieldCode="AU" term="%22Bigbee+CL%22">Bigbee CL</searchLink>; Department of Microbiology and Molecular Genetics, School of Medicine, University of Pittsburgh, Pittsburgh, PA.<br /><searchLink fieldCode="AU" term="%22Venugopalan+R%22">Venugopalan R</searchLink>; Center for Vaccine Research, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15261.; Department of Infectious Diseases and Microbiology, University of Pittsburgh School of Public Health, Pittsburgh, PA.<br /><searchLink fieldCode="AU" term="%22Maiello+P%22">Maiello P</searchLink>; Department of Microbiology and Molecular Genetics, School of Medicine, University of Pittsburgh, Pittsburgh, PA.; Center for Vaccine Research, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15261.<br /><searchLink fieldCode="AU" term="%22Klein+E%22">Klein E</searchLink>; Division of Laboratory Animal Research, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Rodgers+MA%22">Rodgers MA</searchLink>; Department of Microbiology and Molecular Genetics, School of Medicine, University of Pittsburgh, Pittsburgh, PA.; Center for Vaccine Research, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15261.<br /><searchLink fieldCode="AU" term="%22Scanga+CA%22">Scanga CA</searchLink>; Department of Microbiology and Molecular Genetics, School of Medicine, University of Pittsburgh, Pittsburgh, PA.; Center for Vaccine Research, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15261.<br /><searchLink fieldCode="AU" term="%22Lin+PL%22">Lin PL</searchLink>; Center for Vaccine Research, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15261.; Department of Pediatrics, Division of Infectious Disease, Children's Hospital of Pittsburgh of the University of Pittsburgh Medical Center, Pittsburgh, PA.<br /><searchLink fieldCode="AU" term="%22Kirschner+D%22">Kirschner D</searchLink>; 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Chan School of Public Health, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Bryson+BD%22">Bryson BD</searchLink>; Department of Biological Engineering, MIT, Cambridge, MA.; Ragon Institute of Mass General, Harvard, and MIT, Cambridge, MA.<br /><searchLink fieldCode="AU" term="%22Butler+JR%22">Butler JR</searchLink>; The Department of Biomedical Sciences and Technology, AdventHealth University, Orlando, FL.<br /><searchLink fieldCode="AU" term="%22Mattila+JT%22">Mattila JT</searchLink>; Center for Vaccine Research, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15261.; Department of Infectious Diseases and Microbiology, University of Pittsburgh School of Public Health, Pittsburgh, PA.<br /><searchLink fieldCode="AU" term="%22Flynn+JL%22">Flynn JL</searchLink>; Department of Microbiology and Molecular Genetics, School of Medicine, University of Pittsburgh, Pittsburgh, PA.; Center for Vaccine Research, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15261.<br /><searchLink fieldCode="AU" term="%22Angelo+M%22">Angelo M</searchLink>; Department of Pathology, Stanford University School of Medicine, Stanford, CA.
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