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Effect of obesity on the acute response to SARS-CoV-2 infection and development of post-acute sequelae of COVID-19 (PASC) in nonhuman primates.

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Title: Effect of obesity on the acute response to SARS-CoV-2 infection and development of post-acute sequelae of COVID-19 (PASC) in nonhuman primates.
Authors: Sauter KA; Division of Metabolic Health and Disease, Oregon National Primate Research Center (ONPRC), Beaverton, OR, USA., Webb GM; Division of Pathobiology and Immunology, ONPRC., Bader L; Division of Metabolic Health and Disease, Oregon National Primate Research Center (ONPRC), Beaverton, OR, USA., Kreklywich CN; Vaccine and Gene Therapy Institute, Oregon Health and Science University (OHSU), Beaverton, OR, USA., Takahashi DL; Division of Metabolic Health and Disease, Oregon National Primate Research Center (ONPRC), Beaverton, OR, USA., Zaro C; Division of Metabolic Health and Disease, Oregon National Primate Research Center (ONPRC), Beaverton, OR, USA., McGuire CM; Division of Metabolic Health and Disease, Oregon National Primate Research Center (ONPRC), Beaverton, OR, USA., Lewis AD; Division of Comparative Medicine, ONPRC., Colgin LMA; Division of Comparative Medicine, ONPRC., Kirigiti MA; Division of Metabolic Health and Disease, Oregon National Primate Research Center (ONPRC), Beaverton, OR, USA., Blomenkamp H; Division of Metabolic Health and Disease, Oregon National Primate Research Center (ONPRC), Beaverton, OR, USA., Pessoa C; Division of Pathobiology and Immunology, ONPRC., Humkey M; Division of Pathobiology and Immunology, ONPRC., Hulahan J; Department of Pathology and Laboratory Medicine and University of Pennsylvania, Philadelphia, PA, USA., Sleeman M; Department of Microbiology, University of Pennsylvania, Philadelphia, PA, USA., Zweig RC; Division of Comparative Medicine, ONPRC., Thomas S; Division of Neuroscience, ONPRC., Thomas A; Division of Neuroscience, ONPRC., Gao L; Knight Cancer Institute, OHSU, Portland, OR, USA., Hirsch AJ; Vaccine and Gene Therapy Institute, Oregon Health and Science University (OHSU), Beaverton, OR, USA., Levy M; Department of Microbiology, University of Pennsylvania, Philadelphia, PA, USA., Cherry SR; Department of Pathology and Laboratory Medicine and University of Pennsylvania, Philadelphia, PA, USA.; Department of Microbiology, University of Pennsylvania, Philadelphia, PA, USA., Kahn SE; Division of Metabolism, Endocrinology and Nutrition, Department of Medicine, VA Puget Sound Health Care System and University of Washington, Seattle, WA, USA., Slifka MK; Division of Neuroscience, ONPRC., Streblow DN; Division of Pathobiology and Immunology, ONPRC.; Vaccine and Gene Therapy Institute, Oregon Health and Science University (OHSU), Beaverton, OR, USA., Sacha JB; Division of Pathobiology and Immunology, ONPRC., Kievit P; Division of Metabolic Health and Disease, Oregon National Primate Research Center (ONPRC), Beaverton, OR, USA., Roberts CT; Division of Metabolic Health and Disease, Oregon National Primate Research Center (ONPRC), Beaverton, OR, USA.; Division of Reproductive and Developmental Sciences, ONPRC.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Feb 22. Date of Electronic Publication: 2025 Feb 22.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Effect of obesity on the acute response to SARS-CoV-2 infection and development of post-acute sequelae of COVID-19 (PASC) in nonhuman primates.
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  Data: <searchLink fieldCode="AU" term="%22Sauter+KA%22">Sauter KA</searchLink>; Division of Metabolic Health and Disease, Oregon National Primate Research Center (ONPRC), Beaverton, OR, USA.<br /><searchLink fieldCode="AU" term="%22Webb+GM%22">Webb GM</searchLink>; Division of Pathobiology and Immunology, ONPRC.<br /><searchLink fieldCode="AU" term="%22Bader+L%22">Bader L</searchLink>; Division of Metabolic Health and Disease, Oregon National Primate Research Center (ONPRC), Beaverton, OR, USA.<br /><searchLink fieldCode="AU" term="%22Kreklywich+CN%22">Kreklywich CN</searchLink>; Vaccine and Gene Therapy Institute, Oregon Health and Science University (OHSU), Beaverton, OR, USA.<br /><searchLink fieldCode="AU" term="%22Takahashi+DL%22">Takahashi DL</searchLink>; Division of Metabolic Health and Disease, Oregon National Primate Research Center (ONPRC), Beaverton, OR, USA.<br /><searchLink fieldCode="AU" term="%22Zaro+C%22">Zaro C</searchLink>; Division of Metabolic Health and Disease, Oregon National Primate Research Center (ONPRC), Beaverton, OR, USA.<br /><searchLink fieldCode="AU" term="%22McGuire+CM%22">McGuire CM</searchLink>; Division of Metabolic Health and Disease, Oregon National Primate Research Center (ONPRC), Beaverton, OR, USA.<br /><searchLink fieldCode="AU" term="%22Lewis+AD%22">Lewis AD</searchLink>; Division of Comparative Medicine, ONPRC.<br /><searchLink fieldCode="AU" term="%22Colgin+LMA%22">Colgin LMA</searchLink>; Division of Comparative Medicine, ONPRC.<br /><searchLink fieldCode="AU" term="%22Kirigiti+MA%22">Kirigiti MA</searchLink>; Division of Metabolic Health and Disease, Oregon National Primate Research Center (ONPRC), Beaverton, OR, USA.<br /><searchLink fieldCode="AU" term="%22Blomenkamp+H%22">Blomenkamp H</searchLink>; Division of Metabolic Health and Disease, Oregon National Primate Research Center (ONPRC), Beaverton, OR, USA.<br /><searchLink fieldCode="AU" term="%22Pessoa+C%22">Pessoa C</searchLink>; Division of Pathobiology and Immunology, ONPRC.<br /><searchLink fieldCode="AU" term="%22Humkey+M%22">Humkey M</searchLink>; Division of Pathobiology and Immunology, ONPRC.<br /><searchLink fieldCode="AU" term="%22Hulahan+J%22">Hulahan J</searchLink>; Department of Pathology and Laboratory Medicine and University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Sleeman+M%22">Sleeman M</searchLink>; Department of Microbiology, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Zweig+RC%22">Zweig RC</searchLink>; Division of Comparative Medicine, ONPRC.<br /><searchLink fieldCode="AU" term="%22Thomas+S%22">Thomas S</searchLink>; Division of Neuroscience, ONPRC.<br /><searchLink fieldCode="AU" term="%22Thomas+A%22">Thomas A</searchLink>; Division of Neuroscience, ONPRC.<br /><searchLink fieldCode="AU" term="%22Gao+L%22">Gao L</searchLink>; Knight Cancer Institute, OHSU, Portland, OR, USA.<br /><searchLink fieldCode="AU" term="%22Hirsch+AJ%22">Hirsch AJ</searchLink>; Vaccine and Gene Therapy Institute, Oregon Health and Science University (OHSU), Beaverton, OR, USA.<br /><searchLink fieldCode="AU" term="%22Levy+M%22">Levy M</searchLink>; Department of Microbiology, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Cherry+SR%22">Cherry SR</searchLink>; Department of Pathology and Laboratory Medicine and University of Pennsylvania, Philadelphia, PA, USA.; Department of Microbiology, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Kahn+SE%22">Kahn SE</searchLink>; Division of Metabolism, Endocrinology and Nutrition, Department of Medicine, VA Puget Sound Health Care System and University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Slifka+MK%22">Slifka MK</searchLink>; Division of Neuroscience, ONPRC.<br /><searchLink fieldCode="AU" term="%22Streblow+DN%22">Streblow DN</searchLink>; Division of Pathobiology and Immunology, ONPRC.; Vaccine and Gene Therapy Institute, Oregon Health and Science University (OHSU), Beaverton, OR, USA.<br /><searchLink fieldCode="AU" term="%22Sacha+JB%22">Sacha JB</searchLink>; Division of Pathobiology and Immunology, ONPRC.<br /><searchLink fieldCode="AU" term="%22Kievit+P%22">Kievit P</searchLink>; Division of Metabolic Health and Disease, Oregon National Primate Research Center (ONPRC), Beaverton, OR, USA.<br /><searchLink fieldCode="AU" term="%22Roberts+CT%22">Roberts CT</searchLink>; Division of Metabolic Health and Disease, Oregon National Primate Research Center (ONPRC), Beaverton, OR, USA.; Division of Reproductive and Developmental Sciences, ONPRC.
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