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In vivo production of engineered ACE2 decoy protects lungs from SARS-CoV-2 infection.

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Title: In vivo production of engineered ACE2 decoy protects lungs from SARS-CoV-2 infection.
Authors: Suzuki Y; Tsukuba Research Laboratories, Eisai Co., Ltd., Ibaraki 300-2635, Japan., Miyazaki T; Tsukuba Research Laboratories, Eisai Co., Ltd., Ibaraki 300-2635, Japan., Ida Y; Kobe Research Laboratories, Eisai Co., Ltd., Kobe 650-0047, Japan., Suzuki T; Department of Microbiology, Juntendo University School of Medicine, Tokyo 113-8421, Japan.; Research Institute for Microbial Diseases, Osaka University, Osaka 565-0871, Japan., Itoh Y; Department of Microbiology, Juntendo University School of Medicine, Tokyo 113-8421, Japan.; Research Institute for Microbial Diseases, Osaka University, Osaka 565-0871, Japan., Nakao S; Department of Microbiology, Juntendo University School of Medicine, Tokyo 113-8421, Japan., Kondo K; Tsukuba Research Laboratories, Eisai Co., Ltd., Ibaraki 300-2635, Japan., Kubara K; Tsukuba Research Laboratories, Eisai Co., Ltd., Ibaraki 300-2635, Japan., Nishioka K; Department of Infectious Diseases, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan., Muto H; Tsukuba Research Laboratories, Eisai Co., Ltd., Ibaraki 300-2635, Japan., Watari R; Tsukuba Research Laboratories, Eisai Co., Ltd., Ibaraki 300-2635, Japan., Hirayama T; Kobe Research Laboratories, Eisai Co., Ltd., Kobe 650-0047, Japan., Kakiuchi D; Tsukuba Research Laboratories, Eisai Co., Ltd., Ibaraki 300-2635, Japan., Sato S; Tsukuba Research Laboratories, Eisai Co., Ltd., Ibaraki 300-2635, Japan., Inoue S; Tsukuba Research Laboratories, Eisai Co., Ltd., Ibaraki 300-2635, Japan., Uemoto Y; Tsukuba Research Laboratories, Eisai Co., Ltd., Ibaraki 300-2635, Japan., Mukai Y; Kobe Research Laboratories, Eisai Co., Ltd., Kobe 650-0047, Japan., Hoshino A; Department of Cardiovascular Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan., Okamoto T; Department of Microbiology, Juntendo University School of Medicine, Tokyo 113-8421, Japan.; Research Institute for Microbial Diseases, Osaka University, Osaka 565-0871, Japan., Matsui J; Tsukuba Research Laboratories, Eisai Co., Ltd., Ibaraki 300-2635, Japan.
Source: Molecular therapy. Nucleic acids [Mol Ther Nucleic Acids] 2025 Jan 29; Vol. 36 (1), pp. 102467. Date of Electronic Publication: 2025 Jan 29 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101581621 Publication Model: eCollection Cited Medium: Print ISSN: 2162-2531 (Print) Linking ISSN: 21622531 NLM ISO Abbreviation: Mol Ther Nucleic Acids Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: In vivo production of engineered ACE2 decoy protects lungs from SARS-CoV-2 infection.
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  Data: <searchLink fieldCode="AU" term="%22Suzuki+Y%22">Suzuki Y</searchLink>; Tsukuba Research Laboratories, Eisai Co., Ltd., Ibaraki 300-2635, Japan.<br /><searchLink fieldCode="AU" term="%22Miyazaki+T%22">Miyazaki T</searchLink>; Tsukuba Research Laboratories, Eisai Co., Ltd., Ibaraki 300-2635, Japan.<br /><searchLink fieldCode="AU" term="%22Ida+Y%22">Ida Y</searchLink>; Kobe Research Laboratories, Eisai Co., Ltd., Kobe 650-0047, Japan.<br /><searchLink fieldCode="AU" term="%22Suzuki+T%22">Suzuki T</searchLink>; Department of Microbiology, Juntendo University School of Medicine, Tokyo 113-8421, Japan.; Research Institute for Microbial Diseases, Osaka University, Osaka 565-0871, Japan.<br /><searchLink fieldCode="AU" term="%22Itoh+Y%22">Itoh Y</searchLink>; Department of Microbiology, Juntendo University School of Medicine, Tokyo 113-8421, Japan.; Research Institute for Microbial Diseases, Osaka University, Osaka 565-0871, Japan.<br /><searchLink fieldCode="AU" term="%22Nakao+S%22">Nakao S</searchLink>; Department of Microbiology, Juntendo University School of Medicine, Tokyo 113-8421, Japan.<br /><searchLink fieldCode="AU" term="%22Kondo+K%22">Kondo K</searchLink>; Tsukuba Research Laboratories, Eisai Co., Ltd., Ibaraki 300-2635, Japan.<br /><searchLink fieldCode="AU" term="%22Kubara+K%22">Kubara K</searchLink>; Tsukuba Research Laboratories, Eisai Co., Ltd., Ibaraki 300-2635, Japan.<br /><searchLink fieldCode="AU" term="%22Nishioka+K%22">Nishioka K</searchLink>; Department of Infectious Diseases, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan.<br /><searchLink fieldCode="AU" term="%22Muto+H%22">Muto H</searchLink>; Tsukuba Research Laboratories, Eisai Co., Ltd., Ibaraki 300-2635, Japan.<br /><searchLink fieldCode="AU" term="%22Watari+R%22">Watari R</searchLink>; Tsukuba Research Laboratories, Eisai Co., Ltd., Ibaraki 300-2635, Japan.<br /><searchLink fieldCode="AU" term="%22Hirayama+T%22">Hirayama T</searchLink>; Kobe Research Laboratories, Eisai Co., Ltd., Kobe 650-0047, Japan.<br /><searchLink fieldCode="AU" term="%22Kakiuchi+D%22">Kakiuchi D</searchLink>; Tsukuba Research Laboratories, Eisai Co., Ltd., Ibaraki 300-2635, Japan.<br /><searchLink fieldCode="AU" term="%22Sato+S%22">Sato S</searchLink>; Tsukuba Research Laboratories, Eisai Co., Ltd., Ibaraki 300-2635, Japan.<br /><searchLink fieldCode="AU" term="%22Inoue+S%22">Inoue S</searchLink>; Tsukuba Research Laboratories, Eisai Co., Ltd., Ibaraki 300-2635, Japan.<br /><searchLink fieldCode="AU" term="%22Uemoto+Y%22">Uemoto Y</searchLink>; Tsukuba Research Laboratories, Eisai Co., Ltd., Ibaraki 300-2635, Japan.<br /><searchLink fieldCode="AU" term="%22Mukai+Y%22">Mukai Y</searchLink>; Kobe Research Laboratories, Eisai Co., Ltd., Kobe 650-0047, Japan.<br /><searchLink fieldCode="AU" term="%22Hoshino+A%22">Hoshino A</searchLink>; Department of Cardiovascular Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan.<br /><searchLink fieldCode="AU" term="%22Okamoto+T%22">Okamoto T</searchLink>; Department of Microbiology, Juntendo University School of Medicine, Tokyo 113-8421, Japan.; Research Institute for Microbial Diseases, Osaka University, Osaka 565-0871, Japan.<br /><searchLink fieldCode="AU" term="%22Matsui+J%22">Matsui J</searchLink>; Tsukuba Research Laboratories, Eisai Co., Ltd., Ibaraki 300-2635, Japan.
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  Data: <searchLink fieldCode="JN" term="%22101581621%22">Molecular therapy. Nucleic acids</searchLink> [Mol Ther Nucleic Acids] 2025 Jan 29; Vol. 36 (1), pp. 102467. <i>Date of Electronic Publication: </i>2025 Jan 29 (<i>Print Publication: </i>2025).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cell+Press%22">Cell Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101581621 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>2162-2531 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2221622531%22">21622531 </searchLink><i>NLM ISO Abbreviation: </i>Mol Ther Nucleic Acids <i>Subsets: </i>PubMed not MEDLINE
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