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In vivo production of engineered ACE2 decoy protects lungs from SARS-CoV-2 infection.

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Title: In vivo production of engineered ACE2 decoy protects lungs from SARS-CoV-2 infection.
Authors: Suzuki Y; Tsukuba Research Laboratories, Eisai Co., Ltd., Ibaraki 300-2635, Japan., Miyazaki T; Tsukuba Research Laboratories, Eisai Co., Ltd., Ibaraki 300-2635, Japan., Ida Y; Kobe Research Laboratories, Eisai Co., Ltd., Kobe 650-0047, Japan., Suzuki T; Department of Microbiology, Juntendo University School of Medicine, Tokyo 113-8421, Japan.; Research Institute for Microbial Diseases, Osaka University, Osaka 565-0871, Japan., Itoh Y; Department of Microbiology, Juntendo University School of Medicine, Tokyo 113-8421, Japan.; Research Institute for Microbial Diseases, Osaka University, Osaka 565-0871, Japan., Nakao S; Department of Microbiology, Juntendo University School of Medicine, Tokyo 113-8421, Japan., Kondo K; Tsukuba Research Laboratories, Eisai Co., Ltd., Ibaraki 300-2635, Japan., Kubara K; Tsukuba Research Laboratories, Eisai Co., Ltd., Ibaraki 300-2635, Japan., Nishioka K; Department of Infectious Diseases, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan., Muto H; Tsukuba Research Laboratories, Eisai Co., Ltd., Ibaraki 300-2635, Japan., Watari R; Tsukuba Research Laboratories, Eisai Co., Ltd., Ibaraki 300-2635, Japan., Hirayama T; Kobe Research Laboratories, Eisai Co., Ltd., Kobe 650-0047, Japan., Kakiuchi D; Tsukuba Research Laboratories, Eisai Co., Ltd., Ibaraki 300-2635, Japan., Sato S; Tsukuba Research Laboratories, Eisai Co., Ltd., Ibaraki 300-2635, Japan., Inoue S; Tsukuba Research Laboratories, Eisai Co., Ltd., Ibaraki 300-2635, Japan., Uemoto Y; Tsukuba Research Laboratories, Eisai Co., Ltd., Ibaraki 300-2635, Japan., Mukai Y; Kobe Research Laboratories, Eisai Co., Ltd., Kobe 650-0047, Japan., Hoshino A; Department of Cardiovascular Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan., Okamoto T; Department of Microbiology, Juntendo University School of Medicine, Tokyo 113-8421, Japan.; Research Institute for Microbial Diseases, Osaka University, Osaka 565-0871, Japan., Matsui J; Tsukuba Research Laboratories, Eisai Co., Ltd., Ibaraki 300-2635, Japan.
Source: Molecular therapy. Nucleic acids [Mol Ther Nucleic Acids] 2025 Jan 29; Vol. 36 (1), pp. 102467. Date of Electronic Publication: 2025 Jan 29 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101581621 Publication Model: eCollection Cited Medium: Print ISSN: 2162-2531 (Print) Linking ISSN: 21622531 NLM ISO Abbreviation: Mol Ther Nucleic Acids Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2162-2531
DOI:10.1016/j.omtn.2025.102467