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Click-chemistry-derived oxime library reveals efficient reactivators of nerve agent-inhibited butyrylcholinesterase suitable for pseudo-catalytic bioscavenging.

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Title: Click-chemistry-derived oxime library reveals efficient reactivators of nerve agent-inhibited butyrylcholinesterase suitable for pseudo-catalytic bioscavenging.
Authors: Čadež T; Division of Toxicology, Institute for Medical Research and Occupational Health, Zagreb, Croatia., Maček Hrvat N; Division of Toxicology, Institute for Medical Research and Occupational Health, Zagreb, Croatia., Šinko G; Division of Toxicology, Institute for Medical Research and Occupational Health, Zagreb, Croatia., Kalisiak J; Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA, USA., Radić Z; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California at San Diego, La Jolla, CA, USA., Fokin VV; Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA, USA.; The Bridge@USC and Loker Hydrocarbon Research Institute, University of Southern California, Los Angeles, CA, USA., Sharpless KB; Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA, USA., Taylor P; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California at San Diego, La Jolla, CA, USA., Kovarik Z; Division of Toxicology, Institute for Medical Research and Occupational Health, Zagreb, Croatia. zkovarik@imi.hr.; Faculty of Science, University of Zagreb, Zagreb, Croatia. zkovarik@imi.hr.
Source: Archives of toxicology [Arch Toxicol] 2025 May; Vol. 99 (5), pp. 2107-2131. Date of Electronic Publication: 2025 Mar 03.
Publication Type: Journal Article
Journal Info: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0738 (Electronic) Linking ISSN: 03405761 NLM ISO Abbreviation: Arch Toxicol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Click-chemistry-derived oxime library reveals efficient reactivators of nerve agent-inhibited butyrylcholinesterase suitable for pseudo-catalytic bioscavenging.
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  Data: <searchLink fieldCode="AU" term="%22Čadež+T%22">Čadež T</searchLink>; Division of Toxicology, Institute for Medical Research and Occupational Health, Zagreb, Croatia.<br /><searchLink fieldCode="AU" term="%22Maček+Hrvat+N%22">Maček Hrvat N</searchLink>; Division of Toxicology, Institute for Medical Research and Occupational Health, Zagreb, Croatia.<br /><searchLink fieldCode="AU" term="%22Šinko+G%22">Šinko G</searchLink>; Division of Toxicology, Institute for Medical Research and Occupational Health, Zagreb, Croatia.<br /><searchLink fieldCode="AU" term="%22Kalisiak+J%22">Kalisiak J</searchLink>; Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Radić+Z%22">Radić Z</searchLink>; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California at San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Fokin+VV%22">Fokin VV</searchLink>; Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA, USA.; The Bridge@USC and Loker Hydrocarbon Research Institute, University of Southern California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Sharpless+KB%22">Sharpless KB</searchLink>; Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Taylor+P%22">Taylor P</searchLink>; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California at San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Kovarik+Z%22">Kovarik Z</searchLink>; Division of Toxicology, Institute for Medical Research and Occupational Health, Zagreb, Croatia. zkovarik@imi.hr.; Faculty of Science, University of Zagreb, Zagreb, Croatia. zkovarik@imi.hr.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer-Verlag%22">Springer-Verlag </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>0417615 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1432-0738 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203405761%22">03405761 </searchLink><i>NLM ISO Abbreviation: </i>Arch Toxicol <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s00204-025-03985-6
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              Text: 2025 May
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