View in EDS

Single-Cell Analyses Reveal a Functionally Heterogeneous Exhausted CD8+ T-cell Subpopulation That Is Correlated with Response to Checkpoint Therapy in Melanoma.

Saved in:
Bibliographic Details
Title: Single-Cell Analyses Reveal a Functionally Heterogeneous Exhausted CD8+ T-cell Subpopulation That Is Correlated with Response to Checkpoint Therapy in Melanoma.
Authors: Mahuron KM; Department of Surgery, University of California, San Francisco, San Francisco, California.; Department of Surgery, City of Hope National Medical Center, Duarte, California., Shahid O; Department of Immunology, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts.; Gene Lay Institute of Immunology and Inflammation at Brigham and Women's Hospital, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Sao P; Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Wu C; Department of Medicine, University of Arizona, Tucson, Arizona., Haugh AM; Department of Medicine, University of California, San Francisco, San Francisco, California.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California., Huppert LA; Department of Medicine, University of California, San Francisco, San Francisco, California.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California., Levine LS; Department of Medicine, University of California, San Francisco, San Francisco, California.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California., Lowe MM; Department of Dermatology, University of California, San Francisco, San Francisco, California., Alvarado M; Department of Surgery, University of California, San Francisco, San Francisco, California., Micu M; Department of Medicine, University of California, San Francisco, San Francisco, California., Tsai KK; Department of Medicine, University of California, San Francisco, San Francisco, California.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California., Chow M; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California., Singer M; Department of Immunology, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts.; Department of Data Sciences, Dana-Farber Cancer Institute, Boston, Massachusetts., Schenkel JM; Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, Texas.; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas.; Department of Laboratory Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Sharpe AH; Department of Immunology, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts.; Gene Lay Institute of Immunology and Inflammation at Brigham and Women's Hospital, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts., Rosenblum MD; Department of Dermatology, University of California, San Francisco, San Francisco, California., Pauken KE; Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Daud AI; Department of Medicine, University of California, San Francisco, San Francisco, California.
Source: Cancer research [Cancer Res] 2025 Apr 15; Vol. 85 (8), pp. 1424-1440.
Publication Type: Journal Article
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 40042995
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Single-Cell Analyses Reveal a Functionally Heterogeneous Exhausted CD8+ T-cell Subpopulation That Is Correlated with Response to Checkpoint Therapy in Melanoma.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Mahuron+KM%22">Mahuron KM</searchLink>; Department of Surgery, University of California, San Francisco, San Francisco, California.; Department of Surgery, City of Hope National Medical Center, Duarte, California.<br /><searchLink fieldCode="AU" term="%22Shahid+O%22">Shahid O</searchLink>; Department of Immunology, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts.; Gene Lay Institute of Immunology and Inflammation at Brigham and Women's Hospital, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Sao+P%22">Sao P</searchLink>; Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Wu+C%22">Wu C</searchLink>; Department of Medicine, University of Arizona, Tucson, Arizona.<br /><searchLink fieldCode="AU" term="%22Haugh+AM%22">Haugh AM</searchLink>; Department of Medicine, University of California, San Francisco, San Francisco, California.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California.<br /><searchLink fieldCode="AU" term="%22Huppert+LA%22">Huppert LA</searchLink>; Department of Medicine, University of California, San Francisco, San Francisco, California.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California.<br /><searchLink fieldCode="AU" term="%22Levine+LS%22">Levine LS</searchLink>; Department of Medicine, University of California, San Francisco, San Francisco, California.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California.<br /><searchLink fieldCode="AU" term="%22Lowe+MM%22">Lowe MM</searchLink>; Department of Dermatology, University of California, San Francisco, San Francisco, California.<br /><searchLink fieldCode="AU" term="%22Alvarado+M%22">Alvarado M</searchLink>; Department of Surgery, University of California, San Francisco, San Francisco, California.<br /><searchLink fieldCode="AU" term="%22Micu+M%22">Micu M</searchLink>; Department of Medicine, University of California, San Francisco, San Francisco, California.<br /><searchLink fieldCode="AU" term="%22Tsai+KK%22">Tsai KK</searchLink>; Department of Medicine, University of California, San Francisco, San Francisco, California.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California.<br /><searchLink fieldCode="AU" term="%22Chow+M%22">Chow M</searchLink>; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California.<br /><searchLink fieldCode="AU" term="%22Singer+M%22">Singer M</searchLink>; Department of Immunology, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts.; Department of Data Sciences, Dana-Farber Cancer Institute, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Schenkel+JM%22">Schenkel JM</searchLink>; Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, Texas.; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas.; Department of Laboratory Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Sharpe+AH%22">Sharpe AH</searchLink>; Department of Immunology, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts.; Gene Lay Institute of Immunology and Inflammation at Brigham and Women's Hospital, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Rosenblum+MD%22">Rosenblum MD</searchLink>; Department of Dermatology, University of California, San Francisco, San Francisco, California.<br /><searchLink fieldCode="AU" term="%22Pauken+KE%22">Pauken KE</searchLink>; Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Daud+AI%22">Daud AI</searchLink>; Department of Medicine, University of California, San Francisco, San Francisco, California.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%222984705R%22">Cancer research</searchLink> [Cancer Res] 2025 Apr 15; Vol. 85 (8), pp. 1424-1440.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+Cancer+Research%22">American Association for Cancer Research </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>2984705R <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1538-7445 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200085472%22">00085472 </searchLink><i>NLM ISO Abbreviation: </i>Cancer Res <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40042995
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1158/0008-5472.CAN-23-3918
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 1424
    Titles:
      – TitleFull: Single-Cell Analyses Reveal a Functionally Heterogeneous Exhausted CD8+ T-cell Subpopulation That Is Correlated with Response to Checkpoint Therapy in Melanoma.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Mahuron KM
      – PersonEntity:
          Name:
            NameFull: Shahid O
      – PersonEntity:
          Name:
            NameFull: Sao P
      – PersonEntity:
          Name:
            NameFull: Wu C
      – PersonEntity:
          Name:
            NameFull: Haugh AM
      – PersonEntity:
          Name:
            NameFull: Huppert LA
      – PersonEntity:
          Name:
            NameFull: Levine LS
      – PersonEntity:
          Name:
            NameFull: Lowe MM
      – PersonEntity:
          Name:
            NameFull: Alvarado M
      – PersonEntity:
          Name:
            NameFull: Micu M
      – PersonEntity:
          Name:
            NameFull: Tsai KK
      – PersonEntity:
          Name:
            NameFull: Chow M
      – PersonEntity:
          Name:
            NameFull: Singer M
      – PersonEntity:
          Name:
            NameFull: Schenkel JM
      – PersonEntity:
          Name:
            NameFull: Sharpe AH
      – PersonEntity:
          Name:
            NameFull: Rosenblum MD
      – PersonEntity:
          Name:
            NameFull: Pauken KE
      – PersonEntity:
          Name:
            NameFull: Daud AI
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 15
              M: 04
              Text: 2025 Apr 15
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 1538-7445
          Numbering:
            – Type: volume
              Value: 85
            – Type: issue
              Value: 8
          Titles:
            – TitleFull: Cancer research
              Type: main
ResultId 1