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Unprecedented Alkylation of the Catalytic Histidine in the Aging of Cholinesterases after Inhibition by Organophosphorus Pesticides.

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Title: Unprecedented Alkylation of the Catalytic Histidine in the Aging of Cholinesterases after Inhibition by Organophosphorus Pesticides.
Authors: Miller KA; Department of Chemistry and Biochemistry, Ohio State University, Columbus, Ohio 43210, United States., He Y; Department of Chemistry and Biochemistry, Ohio State University, Columbus, Ohio 43210, United States., Allen SK; Department of Chemistry and Biochemistry, Ohio State University, Columbus, Ohio 43210, United States., McElroy CA; InfinixBio, 1507 Chambers Road, Columbus, Ohio 43212, United States., Callam CS; Department of Chemistry and Biochemistry, Ohio State University, Columbus, Ohio 43210, United States., Hadad CM; Department of Chemistry and Biochemistry, Ohio State University, Columbus, Ohio 43210, United States.
Source: Chemical research in toxicology [Chem Res Toxicol] 2025 Mar 17; Vol. 38 (3), pp. 503-518. Date of Electronic Publication: 2025 Mar 05.
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 8807448 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5010 (Electronic) Linking ISSN: 0893228X NLM ISO Abbreviation: Chem Res Toxicol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Unprecedented Alkylation of the Catalytic Histidine in the Aging of Cholinesterases after Inhibition by Organophosphorus Pesticides.
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  Data: <searchLink fieldCode="AU" term="%22Miller+KA%22">Miller KA</searchLink>; Department of Chemistry and Biochemistry, Ohio State University, Columbus, Ohio 43210, United States.<br /><searchLink fieldCode="AU" term="%22He+Y%22">He Y</searchLink>; Department of Chemistry and Biochemistry, Ohio State University, Columbus, Ohio 43210, United States.<br /><searchLink fieldCode="AU" term="%22Allen+SK%22">Allen SK</searchLink>; Department of Chemistry and Biochemistry, Ohio State University, Columbus, Ohio 43210, United States.<br /><searchLink fieldCode="AU" term="%22McElroy+CA%22">McElroy CA</searchLink>; InfinixBio, 1507 Chambers Road, Columbus, Ohio 43212, United States.<br /><searchLink fieldCode="AU" term="%22Callam+CS%22">Callam CS</searchLink>; Department of Chemistry and Biochemistry, Ohio State University, Columbus, Ohio 43210, United States.<br /><searchLink fieldCode="AU" term="%22Hadad+CM%22">Hadad CM</searchLink>; Department of Chemistry and Biochemistry, Ohio State University, Columbus, Ohio 43210, United States.
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  Data: <searchLink fieldCode="JN" term="%228807448%22">Chemical research in toxicology</searchLink> [Chem Res Toxicol] 2025 Mar 17; Vol. 38 (3), pp. 503-518. <i>Date of Electronic Publication: </i>2025 Mar 05.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Chemical+Society%22">American Chemical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8807448 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1520-5010 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%220893228X%22">0893228X </searchLink><i>NLM ISO Abbreviation: </i>Chem Res Toxicol <i>Subsets: </i>MEDLINE
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      – Type: doi
        Value: 10.1021/acs.chemrestox.5c00031
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      – Code: eng
        Text: English
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      – TitleFull: Unprecedented Alkylation of the Catalytic Histidine in the Aging of Cholinesterases after Inhibition by Organophosphorus Pesticides.
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              Text: 2025 Mar 17
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