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Head and neck tumor organoid biobank for modelling individual responses to radiation therapy according to the TP53/HPV status.

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Title: Head and neck tumor organoid biobank for modelling individual responses to radiation therapy according to the TP53/HPV status.
Authors: Issing C; Department of Otorhinolaryngology, Goethe University Frankfurt, University Hospital, Frankfurt/Main, Germany. christian.issing@unimedizin-ffm.de.; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt/Main, Germany. christian.issing@unimedizin-ffm.de.; Frankfurt Cancer Institute, Goethe University Frankfurt, Frankfurt/Main, Germany. christian.issing@unimedizin-ffm.de.; University Cancer Center (UCT) Frankfurt, Goethe University Frankfurt, University Hospital, Frankfurt/Main, Germany. christian.issing@unimedizin-ffm.de.; Mildred-Scheel Early Career Center Frankfurt, Frankfurt/Main, Germany. christian.issing@unimedizin-ffm.de.; German Cancer Consortium (DKTK), Frankfurt/Mainz partner site and German Cancer Research Center (DKFZ), Heidelberg, Germany. christian.issing@unimedizin-ffm.de., Menche C; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt/Main, Germany.; German Cancer Consortium (DKTK), Frankfurt/Mainz partner site and German Cancer Research Center (DKFZ), Heidelberg, Germany., Richter MR; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt/Main, Germany., Mosa MH; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt/Main, Germany.; Frankfurt Cancer Institute, Goethe University Frankfurt, Frankfurt/Main, Germany., von der Grün J; Mildred-Scheel Early Career Center Frankfurt, Frankfurt/Main, Germany.; Department of Radio-oncology, University Hospital Zürich, Zürich, Switzerland., Fleischmann M; Frankfurt Cancer Institute, Goethe University Frankfurt, Frankfurt/Main, Germany.; German Cancer Consortium (DKTK), Frankfurt/Mainz partner site and German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Radiotherapy and Oncology, Goethe University Frankfurt, University Hospital, Frankfurt/Main, Germany., Thoenissen P; Clinic of Oral, Cranio-Maxillofacial and Plastic Facial Surgery, Goethe University Frankfurt, University Hospital, Frankfurt/Main, Germany., Winkelmann R; Dr. Senckenberg Institute for Pathology and Human Genetics, Goethe University Frankfurt, University Hospital, Frankfurt/Main, Germany., Darvishi T; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt/Main, Germany., Loth AG; Department of Otorhinolaryngology, Goethe University Frankfurt, University Hospital, Frankfurt/Main, Germany., Ghanaati S; Clinic of Oral, Cranio-Maxillofacial and Plastic Facial Surgery, Goethe University Frankfurt, University Hospital, Frankfurt/Main, Germany., Rödel F; Frankfurt Cancer Institute, Goethe University Frankfurt, Frankfurt/Main, Germany.; German Cancer Consortium (DKTK), Frankfurt/Mainz partner site and German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Radiotherapy and Oncology, Goethe University Frankfurt, University Hospital, Frankfurt/Main, Germany., Wild PJ; Frankfurt Cancer Institute, Goethe University Frankfurt, Frankfurt/Main, Germany.; University Cancer Center (UCT) Frankfurt, Goethe University Frankfurt, University Hospital, Frankfurt/Main, Germany.; Dr. Senckenberg Institute for Pathology and Human Genetics, Goethe University Frankfurt, University Hospital, Frankfurt/Main, Germany., Brandts CH; Frankfurt Cancer Institute, Goethe University Frankfurt, Frankfurt/Main, Germany.; University Cancer Center (UCT) Frankfurt, Goethe University Frankfurt, University Hospital, Frankfurt/Main, Germany.; German Cancer Consortium (DKTK), Frankfurt/Mainz partner site and German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Medicine, Hematology/Oncology, Goethe University Frankfurt, University Hospital, Frankfurt/Main, Germany., Stöver T; Department of Otorhinolaryngology, Goethe University Frankfurt, University Hospital, Frankfurt/Main, Germany., Farin HF; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt/Main, Germany. h.farin@georg-speyer-haus.de.; Frankfurt Cancer Institute, Goethe University Frankfurt, Frankfurt/Main, Germany. h.farin@georg-speyer-haus.de.; German Cancer Consortium (DKTK), Frankfurt/Mainz partner site and German Cancer Research Center (DKFZ), Heidelberg, Germany. h.farin@georg-speyer-haus.de.
Source: Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2025 Mar 05; Vol. 44 (1), pp. 85. Date of Electronic Publication: 2025 Mar 05.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 8308647 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-9966 (Electronic) Linking ISSN: 03929078 NLM ISO Abbreviation: J Exp Clin Cancer Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Head and neck tumor organoid biobank for modelling individual responses to radiation therapy according to the TP53/HPV status.
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  Data: <searchLink fieldCode="AU" term="%22Issing+C%22">Issing C</searchLink>; Department of Otorhinolaryngology, Goethe University Frankfurt, University Hospital, Frankfurt/Main, Germany. christian.issing@unimedizin-ffm.de.; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt/Main, Germany. christian.issing@unimedizin-ffm.de.; Frankfurt Cancer Institute, Goethe University Frankfurt, Frankfurt/Main, Germany. christian.issing@unimedizin-ffm.de.; University Cancer Center (UCT) Frankfurt, Goethe University Frankfurt, University Hospital, Frankfurt/Main, Germany. christian.issing@unimedizin-ffm.de.; Mildred-Scheel Early Career Center Frankfurt, Frankfurt/Main, Germany. christian.issing@unimedizin-ffm.de.; German Cancer Consortium (DKTK), Frankfurt/Mainz partner site and German Cancer Research Center (DKFZ), Heidelberg, Germany. christian.issing@unimedizin-ffm.de.<br /><searchLink fieldCode="AU" term="%22Menche+C%22">Menche C</searchLink>; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt/Main, Germany.; German Cancer Consortium (DKTK), Frankfurt/Mainz partner site and German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Richter+MR%22">Richter MR</searchLink>; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt/Main, Germany.<br /><searchLink fieldCode="AU" term="%22Mosa+MH%22">Mosa MH</searchLink>; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt/Main, Germany.; Frankfurt Cancer Institute, Goethe University Frankfurt, Frankfurt/Main, Germany.<br /><searchLink fieldCode="AU" term="%22von+der+Grün+J%22">von der Grün J</searchLink>; Mildred-Scheel Early Career Center Frankfurt, Frankfurt/Main, Germany.; Department of Radio-oncology, University Hospital Zürich, Zürich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Fleischmann+M%22">Fleischmann M</searchLink>; Frankfurt Cancer Institute, Goethe University Frankfurt, Frankfurt/Main, Germany.; German Cancer Consortium (DKTK), Frankfurt/Mainz partner site and German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Radiotherapy and Oncology, Goethe University Frankfurt, University Hospital, Frankfurt/Main, Germany.<br /><searchLink fieldCode="AU" term="%22Thoenissen+P%22">Thoenissen P</searchLink>; Clinic of Oral, Cranio-Maxillofacial and Plastic Facial Surgery, Goethe University Frankfurt, University Hospital, Frankfurt/Main, Germany.<br /><searchLink fieldCode="AU" term="%22Winkelmann+R%22">Winkelmann R</searchLink>; Dr. Senckenberg Institute for Pathology and Human Genetics, Goethe University Frankfurt, University Hospital, Frankfurt/Main, Germany.<br /><searchLink fieldCode="AU" term="%22Darvishi+T%22">Darvishi T</searchLink>; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt/Main, Germany.<br /><searchLink fieldCode="AU" term="%22Loth+AG%22">Loth AG</searchLink>; Department of Otorhinolaryngology, Goethe University Frankfurt, University Hospital, Frankfurt/Main, Germany.<br /><searchLink fieldCode="AU" term="%22Ghanaati+S%22">Ghanaati S</searchLink>; Clinic of Oral, Cranio-Maxillofacial and Plastic Facial Surgery, Goethe University Frankfurt, University Hospital, Frankfurt/Main, Germany.<br /><searchLink fieldCode="AU" term="%22Rödel+F%22">Rödel F</searchLink>; Frankfurt Cancer Institute, Goethe University Frankfurt, Frankfurt/Main, Germany.; German Cancer Consortium (DKTK), Frankfurt/Mainz partner site and German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Radiotherapy and Oncology, Goethe University Frankfurt, University Hospital, Frankfurt/Main, Germany.<br /><searchLink fieldCode="AU" term="%22Wild+PJ%22">Wild PJ</searchLink>; Frankfurt Cancer Institute, Goethe University Frankfurt, Frankfurt/Main, Germany.; University Cancer Center (UCT) Frankfurt, Goethe University Frankfurt, University Hospital, Frankfurt/Main, Germany.; Dr. Senckenberg Institute for Pathology and Human Genetics, Goethe University Frankfurt, University Hospital, Frankfurt/Main, Germany.<br /><searchLink fieldCode="AU" term="%22Brandts+CH%22">Brandts CH</searchLink>; Frankfurt Cancer Institute, Goethe University Frankfurt, Frankfurt/Main, Germany.; University Cancer Center (UCT) Frankfurt, Goethe University Frankfurt, University Hospital, Frankfurt/Main, Germany.; German Cancer Consortium (DKTK), Frankfurt/Mainz partner site and German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Medicine, Hematology/Oncology, Goethe University Frankfurt, University Hospital, Frankfurt/Main, Germany.<br /><searchLink fieldCode="AU" term="%22Stöver+T%22">Stöver T</searchLink>; Department of Otorhinolaryngology, Goethe University Frankfurt, University Hospital, Frankfurt/Main, Germany.<br /><searchLink fieldCode="AU" term="%22Farin+HF%22">Farin HF</searchLink>; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt/Main, Germany. h.farin@georg-speyer-haus.de.; Frankfurt Cancer Institute, Goethe University Frankfurt, Frankfurt/Main, Germany. h.farin@georg-speyer-haus.de.; German Cancer Consortium (DKTK), Frankfurt/Mainz partner site and German Cancer Research Center (DKFZ), Heidelberg, Germany. h.farin@georg-speyer-haus.de.
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  Data: <searchLink fieldCode="JN" term="%228308647%22">Journal of experimental & clinical cancer research : CR</searchLink> [J Exp Clin Cancer Res] 2025 Mar 05; Vol. 44 (1), pp. 85. <i>Date of Electronic Publication: </i>2025 Mar 05.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>8308647 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1756-9966 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203929078%22">03929078 </searchLink><i>NLM ISO Abbreviation: </i>J Exp Clin Cancer Res <i>Subsets: </i>MEDLINE
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              Text: 2025 Mar 05
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