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Downregulation of NAD Kinase Expression in β-Cells Contributes to the Aging-Associated Decline in Glucose-Stimulated Insulin Secretion.

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Title: Downregulation of NAD Kinase Expression in β-Cells Contributes to the Aging-Associated Decline in Glucose-Stimulated Insulin Secretion.
Authors: Li GJ; Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan., Cheng ML; Metabolomics Core Laboratory, Healthy Aging Research Center, Chang Gung University, Taoyuan, Taiwan.; Clinical Metabolomics Core Laboratory, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.; Department of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan., Lin YT; School of Physical Therapy, College of Medicine, Chang Gung University, Taoyuan, Taiwan., Ho YH; Department of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan., Lin G; Clinical Metabolomics Core Laboratory, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.; Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital at Linkou and Chang Gung University, Taoyuan, Taiwan.; Department of Medical Imaging and Radiological Sciences, Chang Gung University, Taoyuan, Taiwan., Chiu CY; Clinical Metabolomics Core Laboratory, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.; Department of Pediatrics, Chang Gung Memorial Hospital at Linkou, and Chang Gung University, Taoyuan, Taiwan.; Department of Pediatrics, Chang Gung Memorial Hospital at Keelung, and Chang Gung University, Taoyuan, Taiwan., Ho HY; Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan.; Metabolomics Core Laboratory, Healthy Aging Research Center, Chang Gung University, Taoyuan, Taiwan.; Clinical Metabolomics Core Laboratory, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.; Department of Medical Biotechnology and Laboratory Science, College of Medicine, Chang Gung University, Taoyuan, Taiwan.; Research Center for Emerging Viral Infections, Chang Gung University, Taoyuan, Taiwan.
Source: Aging cell [Aging Cell] 2025 Apr; Vol. 24 (4), pp. e70037. Date of Electronic Publication: 2025 Mar 05.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-9726 (Electronic) Linking ISSN: 14749718 NLM ISO Abbreviation: Aging Cell Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Downregulation of NAD Kinase Expression in β-Cells Contributes to the Aging-Associated Decline in Glucose-Stimulated Insulin Secretion.
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  Data: <searchLink fieldCode="AU" term="%22Li+GJ%22">Li GJ</searchLink>; Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Cheng+ML%22">Cheng ML</searchLink>; Metabolomics Core Laboratory, Healthy Aging Research Center, Chang Gung University, Taoyuan, Taiwan.; Clinical Metabolomics Core Laboratory, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.; Department of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+YT%22">Lin YT</searchLink>; School of Physical Therapy, College of Medicine, Chang Gung University, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Ho+YH%22">Ho YH</searchLink>; Department of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+G%22">Lin G</searchLink>; Clinical Metabolomics Core Laboratory, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.; Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital at Linkou and Chang Gung University, Taoyuan, Taiwan.; Department of Medical Imaging and Radiological Sciences, Chang Gung University, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chiu+CY%22">Chiu CY</searchLink>; Clinical Metabolomics Core Laboratory, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.; Department of Pediatrics, Chang Gung Memorial Hospital at Linkou, and Chang Gung University, Taoyuan, Taiwan.; Department of Pediatrics, Chang Gung Memorial Hospital at Keelung, and Chang Gung University, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Ho+HY%22">Ho HY</searchLink>; Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan.; Metabolomics Core Laboratory, Healthy Aging Research Center, Chang Gung University, Taoyuan, Taiwan.; Clinical Metabolomics Core Laboratory, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.; Department of Medical Biotechnology and Laboratory Science, College of Medicine, Chang Gung University, Taoyuan, Taiwan.; Research Center for Emerging Viral Infections, Chang Gung University, Taoyuan, Taiwan.
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  Data: <searchLink fieldCode="JN" term="%22101130839%22">Aging cell</searchLink> [Aging Cell] 2025 Apr; Vol. 24 (4), pp. e70037. <i>Date of Electronic Publication: </i>2025 Mar 05.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley-Blackwell%22">Wiley-Blackwell </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101130839 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1474-9726 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214749718%22">14749718 </searchLink><i>NLM ISO Abbreviation: </i>Aging Cell <i>Subsets: </i>MEDLINE
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        Value: 10.1111/acel.70037
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      – Code: eng
        Text: English
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              Text: 2025 Apr
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              Y: 2025
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