Targeting CXCR2 signaling in inflammatory lung diseases: neutrophil-driven inflammation and emerging therapies.

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Title: Targeting CXCR2 signaling in inflammatory lung diseases: neutrophil-driven inflammation and emerging therapies.
Authors: Hussain MS; Uttaranchal Institute of Pharmaceutical Sciences, Uttaranchal University, Dehradun, India., Goyal A; Institute of Pharmaceutical Research, GLA University, Mathura, U.P, India., Goyal K; Department of Biotechnology, Graphic Era (Deemed to Be University), Clement Town, 248002, Dehradun, India., S RJ; Department of Biotechnology and Genetics, Jain (Deemed-to-Be) University, Bengaluru, Karnataka, 560069, India., Nellore J; Department of Biotechnology, Sathyabama Institute of Science and Technology, Chennai, Tamil Nadu, India., Shahwan M; Centre of Medical and Bio-Allied Health Sciences Research, Ajman University, Ajman, United Arab Emirates., Rekha A; Dr. D. Y. Patil Medical College, Hospital and Research Centre, Pimpri, Pune, India., Ali H; Centre for Global Health Research, Saveetha Medical College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India., Dhanasekaran M; Department of Drug Discovery and Development, Harrison College of Pharmacy, Auburn University, Auburn, AL, USA., MacLoughlin R; Aerogen Ltd, Galway Business Park, Galway, Ireland.; School of Pharmacy & Biomolecular Sciences, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.; School of Pharmacy & Pharmaceutical Sciences, Trinity College, Dublin, D02 PN40, Ireland., Dua K; Faculty of Health, Australian Research Centre in Complementary and Integrative Medicine, University of Technology Sydney, Ultimo, Australia.; Discipline of Pharmacy, Graduate School of Health, The University of Technology Sydney, Ultimo, NSW, 2007, Australia., Gupta G; Centre of Medical and Bio-Allied Health Sciences Research, Ajman University, Ajman, United Arab Emirates. gaurav.gupta@chitkara.edu.in.; Centre for Research Impact & Outcome, Chitkara College of Pharmacy, Chitkara University, Rajpura, Punjab, 140401, India. gaurav.gupta@chitkara.edu.in.
Source: Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2025 Aug; Vol. 398 (8), pp. 9583-9607. Date of Electronic Publication: 2025 Mar 06.
Publication Type: Journal Article; Review
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1912 (Electronic) Linking ISSN: 00281298 NLM ISO Abbreviation: Naunyn Schmiedebergs Arch Pharmacol Subsets: MEDLINE
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  Data: Targeting CXCR2 signaling in inflammatory lung diseases: neutrophil-driven inflammation and emerging therapies.
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  Data: <searchLink fieldCode="AU" term="%22Hussain+MS%22">Hussain MS</searchLink>; Uttaranchal Institute of Pharmaceutical Sciences, Uttaranchal University, Dehradun, India.<br /><searchLink fieldCode="AU" term="%22Goyal+A%22">Goyal A</searchLink>; Institute of Pharmaceutical Research, GLA University, Mathura, U.P, India.<br /><searchLink fieldCode="AU" term="%22Goyal+K%22">Goyal K</searchLink>; Department of Biotechnology, Graphic Era (Deemed to Be University), Clement Town, 248002, Dehradun, India.<br /><searchLink fieldCode="AU" term="%22S+RJ%22">S RJ</searchLink>; Department of Biotechnology and Genetics, Jain (Deemed-to-Be) University, Bengaluru, Karnataka, 560069, India.<br /><searchLink fieldCode="AU" term="%22Nellore+J%22">Nellore J</searchLink>; Department of Biotechnology, Sathyabama Institute of Science and Technology, Chennai, Tamil Nadu, India.<br /><searchLink fieldCode="AU" term="%22Shahwan+M%22">Shahwan M</searchLink>; Centre of Medical and Bio-Allied Health Sciences Research, Ajman University, Ajman, United Arab Emirates.<br /><searchLink fieldCode="AU" term="%22Rekha+A%22">Rekha A</searchLink>; Dr. D. Y. Patil Medical College, Hospital and Research Centre, Pimpri, Pune, India.<br /><searchLink fieldCode="AU" term="%22Ali+H%22">Ali H</searchLink>; Centre for Global Health Research, Saveetha Medical College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India.<br /><searchLink fieldCode="AU" term="%22Dhanasekaran+M%22">Dhanasekaran M</searchLink>; Department of Drug Discovery and Development, Harrison College of Pharmacy, Auburn University, Auburn, AL, USA.<br /><searchLink fieldCode="AU" term="%22MacLoughlin+R%22">MacLoughlin R</searchLink>; Aerogen Ltd, Galway Business Park, Galway, Ireland.; School of Pharmacy & Biomolecular Sciences, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.; School of Pharmacy & Pharmaceutical Sciences, Trinity College, Dublin, D02 PN40, Ireland.<br /><searchLink fieldCode="AU" term="%22Dua+K%22">Dua K</searchLink>; Faculty of Health, Australian Research Centre in Complementary and Integrative Medicine, University of Technology Sydney, Ultimo, Australia.; Discipline of Pharmacy, Graduate School of Health, The University of Technology Sydney, Ultimo, NSW, 2007, Australia.<br /><searchLink fieldCode="AU" term="%22Gupta+G%22">Gupta G</searchLink>; Centre of Medical and Bio-Allied Health Sciences Research, Ajman University, Ajman, United Arab Emirates. gaurav.gupta@chitkara.edu.in.; Centre for Research Impact & Outcome, Chitkara College of Pharmacy, Chitkara University, Rajpura, Punjab, 140401, India. gaurav.gupta@chitkara.edu.in.
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