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Tau levels in platelets isolated from Huntington's disease patients serve as a biomarker of disease severity.

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Title: Tau levels in platelets isolated from Huntington's disease patients serve as a biomarker of disease severity.
Authors: Alpaugh M; Department of Molecular and Cellular Biology, University of Guelph, Guelph, Canada. alpaughm@uoguelph.ca., Lantero-Rodriguez J; Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy at University of Gothenburg, Mölndal, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden., Benedet AL; Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy at University of Gothenburg, Mölndal, Sweden.; Translational Neuroimaging Laboratory, McGill University Research Centre for Studies in Aging, Douglas Research Institute, Le Centre Intégré Universitaire de Santé et de Services Sociaux (CIUSSS) de l'Ouest-de-L'Île-de-Montréal, Montreal, Canada., Manseau U; Department of Mathematical and Industrial Engineering, Polytechnique Montreal, Montreal, Canada., Boutin M; Département de Psychiatrie & Neurosciences, Faculté de Médecine, Université Laval, Quebec, Canada., Maiuri M; Department of Molecular and Cellular Biology, University of Guelph, Guelph, Canada., Denis HL; Département de Psychiatrie & Neurosciences, Faculté de Médecine, Université Laval, Quebec, Canada., Masnata M; Département de Psychiatrie & Neurosciences, Faculté de Médecine, Université Laval, Quebec, Canada., Fazal SV; Department of Clinical Neurosciences, John Van Geest Centre for Brain Repair, University of Cambridge, Cambridge, UK., Chouinard S; Department of Movement Disorders, Centre Hospitalier Universitaire de Montréal-Hôtel Dieu, CHUM, Montréal, Canada., Rosa-Neto P; Translational Neuroimaging Laboratory, McGill University Research Centre for Studies in Aging, Douglas Research Institute, Le Centre Intégré Universitaire de Santé et de Services Sociaux (CIUSSS) de l'Ouest-de-L'Île-de-Montréal, Montreal, Canada.; Montreal Neurological Institute, Montreal, Canada.; Peter O'Donnell Jr. Brain Institute (OBI), University of Texas Southwestern Medical Centre (UTSW), Dallas, USA., Barker RA; Department of Clinical Neurosciences, John Van Geest Centre for Brain Repair, University of Cambridge, Cambridge, UK., Blennow K; Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy at University of Gothenburg, Mölndal, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden., Zetterberg H; Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy at University of Gothenburg, Mölndal, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.; Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London, UK.; UK Dementia Research Institute at UCL, London, UK.; Hong Kong Center for Neurodegenerative Diseases, Hong Kong, China.; Wisconsin Alzheimer's Disease Research Center, University of Wisconsin School of Medicine and Public Health, University of Wisconsin-Madison, Madison, USA., Labib R; Department of Mathematical and Industrial Engineering, Polytechnique Montreal, Montreal, Canada., Cicchetti F; Département de Psychiatrie & Neurosciences, Faculté de Médecine, Université Laval, Quebec, Canada. francesca.cicchetti@crchudequebec.ulaval.ca.; Centre de Recherche du CHU de Québec - Université Laval, Axe Neurosciences, Québec, Canada. francesca.cicchetti@crchudequebec.ulaval.ca.
Source: Journal of neurology [J Neurol] 2025 Mar 06; Vol. 272 (3), pp. 254. Date of Electronic Publication: 2025 Mar 06.
Publication Type: Journal Article
Journal Info: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0423161 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-1459 (Electronic) Linking ISSN: 03405354 NLM ISO Abbreviation: J Neurol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Tau levels in platelets isolated from Huntington's disease patients serve as a biomarker of disease severity.
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  Data: <searchLink fieldCode="AU" term="%22Alpaugh+M%22">Alpaugh M</searchLink>; Department of Molecular and Cellular Biology, University of Guelph, Guelph, Canada. alpaughm@uoguelph.ca.<br /><searchLink fieldCode="AU" term="%22Lantero-Rodriguez+J%22">Lantero-Rodriguez J</searchLink>; Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy at University of Gothenburg, Mölndal, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.<br /><searchLink fieldCode="AU" term="%22Benedet+AL%22">Benedet AL</searchLink>; Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy at University of Gothenburg, Mölndal, Sweden.; Translational Neuroimaging Laboratory, McGill University Research Centre for Studies in Aging, Douglas Research Institute, Le Centre Intégré Universitaire de Santé et de Services Sociaux (CIUSSS) de l'Ouest-de-L'Île-de-Montréal, Montreal, Canada.<br /><searchLink fieldCode="AU" term="%22Manseau+U%22">Manseau U</searchLink>; Department of Mathematical and Industrial Engineering, Polytechnique Montreal, Montreal, Canada.<br /><searchLink fieldCode="AU" term="%22Boutin+M%22">Boutin M</searchLink>; Département de Psychiatrie & Neurosciences, Faculté de Médecine, Université Laval, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Maiuri+M%22">Maiuri M</searchLink>; Department of Molecular and Cellular Biology, University of Guelph, Guelph, Canada.<br /><searchLink fieldCode="AU" term="%22Denis+HL%22">Denis HL</searchLink>; Département de Psychiatrie & Neurosciences, Faculté de Médecine, Université Laval, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Masnata+M%22">Masnata M</searchLink>; Département de Psychiatrie & Neurosciences, Faculté de Médecine, Université Laval, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Fazal+SV%22">Fazal SV</searchLink>; Department of Clinical Neurosciences, John Van Geest Centre for Brain Repair, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Chouinard+S%22">Chouinard S</searchLink>; Department of Movement Disorders, Centre Hospitalier Universitaire de Montréal-Hôtel Dieu, CHUM, Montréal, Canada.<br /><searchLink fieldCode="AU" term="%22Rosa-Neto+P%22">Rosa-Neto P</searchLink>; Translational Neuroimaging Laboratory, McGill University Research Centre for Studies in Aging, Douglas Research Institute, Le Centre Intégré Universitaire de Santé et de Services Sociaux (CIUSSS) de l'Ouest-de-L'Île-de-Montréal, Montreal, Canada.; Montreal Neurological Institute, Montreal, Canada.; Peter O'Donnell Jr. Brain Institute (OBI), University of Texas Southwestern Medical Centre (UTSW), Dallas, USA.<br /><searchLink fieldCode="AU" term="%22Barker+RA%22">Barker RA</searchLink>; Department of Clinical Neurosciences, John Van Geest Centre for Brain Repair, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Blennow+K%22">Blennow K</searchLink>; Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy at University of Gothenburg, Mölndal, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.<br /><searchLink fieldCode="AU" term="%22Zetterberg+H%22">Zetterberg H</searchLink>; Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy at University of Gothenburg, Mölndal, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.; Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London, UK.; UK Dementia Research Institute at UCL, London, UK.; Hong Kong Center for Neurodegenerative Diseases, Hong Kong, China.; Wisconsin Alzheimer's Disease Research Center, University of Wisconsin School of Medicine and Public Health, University of Wisconsin-Madison, Madison, USA.<br /><searchLink fieldCode="AU" term="%22Labib+R%22">Labib R</searchLink>; Department of Mathematical and Industrial Engineering, Polytechnique Montreal, Montreal, Canada.<br /><searchLink fieldCode="AU" term="%22Cicchetti+F%22">Cicchetti F</searchLink>; Département de Psychiatrie & Neurosciences, Faculté de Médecine, Université Laval, Quebec, Canada. francesca.cicchetti@crchudequebec.ulaval.ca.; Centre de Recherche du CHU de Québec - Université Laval, Axe Neurosciences, Québec, Canada. francesca.cicchetti@crchudequebec.ulaval.ca.
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