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Estrogen influences class-switched memory B cell frequency only in humans with two X chromosomes.

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Title: Estrogen influences class-switched memory B cell frequency only in humans with two X chromosomes.
Authors: Peckham H; Centre for Adolescent Rheumatology Versus Arthritis at UCL, UCLH and GOSH , London, UK.; Centre for Rheumatology, University College London , London, UK.; Infection, Immunity and Inflammation Research and Teaching Department - UCL Great Ormond Street Institute of Child Health , London, UK., Radziszewska A; Centre for Adolescent Rheumatology Versus Arthritis at UCL, UCLH and GOSH , London, UK.; Centre for Rheumatology, University College London , London, UK., Sikora J; Centre for Immunobiology, Blizard Institute, Queen Mary University of London , London, UK., de Gruijter NM; Centre for Adolescent Rheumatology Versus Arthritis at UCL, UCLH and GOSH , London, UK.; Centre for Rheumatology, University College London , London, UK., Restuadi R; Centre for Adolescent Rheumatology Versus Arthritis at UCL, UCLH and GOSH , London, UK.; Infection, Immunity and Inflammation Research and Teaching Department - UCL Great Ormond Street Institute of Child Health , London, UK., Kartawinata M; Centre for Adolescent Rheumatology Versus Arthritis at UCL, UCLH and GOSH , London, UK.; Infection, Immunity and Inflammation Research and Teaching Department - UCL Great Ormond Street Institute of Child Health , London, UK., Martin-Gutierrez L; Centre for Adolescent Rheumatology Versus Arthritis at UCL, UCLH and GOSH , London, UK.; Centre for Rheumatology, University College London , London, UK., Robinson GA; Centre for Adolescent Rheumatology Versus Arthritis at UCL, UCLH and GOSH , London, UK.; Centre for Rheumatology, University College London , London, UK., Deakin CT; Centre for Adolescent Rheumatology Versus Arthritis at UCL, UCLH and GOSH , London, UK.; Infection, Immunity and Inflammation Research and Teaching Department - UCL Great Ormond Street Institute of Child Health , London, UK.; NIHR Biomedical Research Centre at Great Ormond Street Hospital , London, UK.; School of Population Health, Faculty of Medicine and Health, University of New South Wales, Sydney, Australia., Wedderburn LR; Centre for Adolescent Rheumatology Versus Arthritis at UCL, UCLH and GOSH , London, UK.; Infection, Immunity and Inflammation Research and Teaching Department - UCL Great Ormond Street Institute of Child Health , London, UK.; NIHR Biomedical Research Centre at Great Ormond Street Hospital , London, UK., Jury EC; Centre for Adolescent Rheumatology Versus Arthritis at UCL, UCLH and GOSH , London, UK.; Centre for Rheumatology, University College London , London, UK., Butler G; Infection, Immunity and Inflammation Research and Teaching Department - UCL Great Ormond Street Institute of Child Health , London, UK.; University College London Hospital , London, UK., Chambers ES; Centre for Immunobiology, Blizard Institute, Queen Mary University of London , London, UK., Rosser EC; Centre for Adolescent Rheumatology Versus Arthritis at UCL, UCLH and GOSH , London, UK.; Centre for Rheumatology, University College London , London, UK., Ciurtin C; Centre for Adolescent Rheumatology Versus Arthritis at UCL, UCLH and GOSH , London, UK.; Centre for Rheumatology, University College London , London, UK.; University College London Hospital , London, UK.
Source: The Journal of experimental medicine [J Exp Med] 2025 Apr 07; Vol. 222 (4). Date of Electronic Publication: 2025 Mar 06.
Publication Type: Journal Article
Journal Info: Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 2985109R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1540-9538 (Electronic) Linking ISSN: 00221007 NLM ISO Abbreviation: J Exp Med Subsets: MEDLINE
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  Data: Estrogen influences class-switched memory B cell frequency only in humans with two X chromosomes.
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  Data: <searchLink fieldCode="AU" term="%22Peckham+H%22">Peckham H</searchLink>; Centre for Adolescent Rheumatology Versus Arthritis at UCL, UCLH and GOSH , London, UK.; Centre for Rheumatology, University College London , London, UK.; Infection, Immunity and Inflammation Research and Teaching Department - UCL Great Ormond Street Institute of Child Health , London, UK.<br /><searchLink fieldCode="AU" term="%22Radziszewska+A%22">Radziszewska A</searchLink>; Centre for Adolescent Rheumatology Versus Arthritis at UCL, UCLH and GOSH , London, UK.; Centre for Rheumatology, University College London , London, UK.<br /><searchLink fieldCode="AU" term="%22Sikora+J%22">Sikora J</searchLink>; Centre for Immunobiology, Blizard Institute, Queen Mary University of London , London, UK.<br /><searchLink fieldCode="AU" term="%22de+Gruijter+NM%22">de Gruijter NM</searchLink>; Centre for Adolescent Rheumatology Versus Arthritis at UCL, UCLH and GOSH , London, UK.; Centre for Rheumatology, University College London , London, UK.<br /><searchLink fieldCode="AU" term="%22Restuadi+R%22">Restuadi R</searchLink>; Centre for Adolescent Rheumatology Versus Arthritis at UCL, UCLH and GOSH , London, UK.; Infection, Immunity and Inflammation Research and Teaching Department - UCL Great Ormond Street Institute of Child Health , London, UK.<br /><searchLink fieldCode="AU" term="%22Kartawinata+M%22">Kartawinata M</searchLink>; Centre for Adolescent Rheumatology Versus Arthritis at UCL, UCLH and GOSH , London, UK.; Infection, Immunity and Inflammation Research and Teaching Department - UCL Great Ormond Street Institute of Child Health , London, UK.<br /><searchLink fieldCode="AU" term="%22Martin-Gutierrez+L%22">Martin-Gutierrez L</searchLink>; Centre for Adolescent Rheumatology Versus Arthritis at UCL, UCLH and GOSH , London, UK.; Centre for Rheumatology, University College London , London, UK.<br /><searchLink fieldCode="AU" term="%22Robinson+GA%22">Robinson GA</searchLink>; Centre for Adolescent Rheumatology Versus Arthritis at UCL, UCLH and GOSH , London, UK.; Centre for Rheumatology, University College London , London, UK.<br /><searchLink fieldCode="AU" term="%22Deakin+CT%22">Deakin CT</searchLink>; Centre for Adolescent Rheumatology Versus Arthritis at UCL, UCLH and GOSH , London, UK.; Infection, Immunity and Inflammation Research and Teaching Department - UCL Great Ormond Street Institute of Child Health , London, UK.; NIHR Biomedical Research Centre at Great Ormond Street Hospital , London, UK.; School of Population Health, Faculty of Medicine and Health, University of New South Wales, Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22Wedderburn+LR%22">Wedderburn LR</searchLink>; Centre for Adolescent Rheumatology Versus Arthritis at UCL, UCLH and GOSH , London, UK.; Infection, Immunity and Inflammation Research and Teaching Department - UCL Great Ormond Street Institute of Child Health , London, UK.; NIHR Biomedical Research Centre at Great Ormond Street Hospital , London, UK.<br /><searchLink fieldCode="AU" term="%22Jury+EC%22">Jury EC</searchLink>; Centre for Adolescent Rheumatology Versus Arthritis at UCL, UCLH and GOSH , London, UK.; Centre for Rheumatology, University College London , London, UK.<br /><searchLink fieldCode="AU" term="%22Butler+G%22">Butler G</searchLink>; Infection, Immunity and Inflammation Research and Teaching Department - UCL Great Ormond Street Institute of Child Health , London, UK.; University College London Hospital , London, UK.<br /><searchLink fieldCode="AU" term="%22Chambers+ES%22">Chambers ES</searchLink>; Centre for Immunobiology, Blizard Institute, Queen Mary University of London , London, UK.<br /><searchLink fieldCode="AU" term="%22Rosser+EC%22">Rosser EC</searchLink>; Centre for Adolescent Rheumatology Versus Arthritis at UCL, UCLH and GOSH , London, UK.; Centre for Rheumatology, University College London , London, UK.<br /><searchLink fieldCode="AU" term="%22Ciurtin+C%22">Ciurtin C</searchLink>; Centre for Adolescent Rheumatology Versus Arthritis at UCL, UCLH and GOSH , London, UK.; Centre for Rheumatology, University College London , London, UK.; University College London Hospital , London, UK.
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  Data: <searchLink fieldCode="JN" term="%222985109R%22">The Journal of experimental medicine</searchLink> [J Exp Med] 2025 Apr 07; Vol. 222 (4). <i>Date of Electronic Publication: </i>2025 Mar 06.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Rockefeller+University+Press%22">Rockefeller University Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>2985109R <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1540-9538 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200221007%22">00221007 </searchLink><i>NLM ISO Abbreviation: </i>J Exp Med <i>Subsets: </i>MEDLINE
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        Value: 10.1084/jem.20241253
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