An engineered Treg selective immunocytokine induces sustained immune modulation in a preclinical model of hemophilia A.
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| Title: | An engineered Treg selective immunocytokine induces sustained immune modulation in a preclinical model of hemophilia A. |
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| Authors: | Rana J; Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, USA., VanDyke D; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, Maryland, USA; Translational Tissue Engineering Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Muñoz-Melero M; Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, USA., Fabilane CS; Translational Tissue Engineering Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; Program in Molecular Biophysics, Johns Hopkins University, Baltimore, Maryland, USA., Thirumurugan S; Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, USA., Arisa S; Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, USA., Zhou B; Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, USA., Spangler JB; Program in Molecular Biophysics, Johns Hopkins University, Baltimore, Maryland, USA; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; Bloomberg∼Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University, Baltimore, Maryland, USA; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland, USA; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; Department of Molecular Microbiology and Immunology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USA. Electronic address: jamie.spangler@jhu.edu., Biswas M; Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, USA. Electronic address: nbiswas@iu.edu. |
| Source: | Journal of thrombosis and haemostasis : JTH [J Thromb Haemost] 2025 Jun; Vol. 23 (6), pp. 1800-1809. Date of Electronic Publication: 2025 Mar 06. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: Elsevier Country of Publication: England NLM ID: 101170508 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7836 (Electronic) Linking ISSN: 15387836 NLM ISO Abbreviation: J Thromb Haemost Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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