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A Phase 2 Study of Multiparametric Magnetic Resonance Imaging-Guided High-Dose Response-Adaptive Radiation Therapy With Concurrent Temozolomide in Patients With Newly Diagnosed Glioblastoma: Results From an Interim Analysis.

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Title: A Phase 2 Study of Multiparametric Magnetic Resonance Imaging-Guided High-Dose Response-Adaptive Radiation Therapy With Concurrent Temozolomide in Patients With Newly Diagnosed Glioblastoma: Results From an Interim Analysis.
Authors: Kim MM; Department of Radiation Oncology, The University of Michigan, Ann Arbor, Michigan. Electronic address: michekim@med.umich.edu., Aryal MP; Department of Radiation Oncology, The University of Michigan, Ann Arbor, Michigan., Suresh K; Department of Radiation Oncology, The University of Michigan, Ann Arbor, Michigan; Department of Biostatistics, The University of Michigan, Ann Arbor, Michigan., Rosen BS; Department of Radiation Oncology, The University of Michigan, Ann Arbor, Michigan., Parmar H; Department of Radiology, The University of Michigan, Ann Arbor, Michigan., You D; Department of Radiation Oncology, The University of Michigan, Ann Arbor, Michigan., Leung D; Department of Neurology, The University of Michigan, Ann Arbor, Michigan., Clarke N; Department of Neurology, The University of Michigan, Ann Arbor, Michigan., Fortunato J; Department of Neurology, The University of Michigan, Ann Arbor, Michigan., Al-Holou W; Department of Neurosurgery, The University of Michigan, Ann Arbor, Michigan., Heth J; Department of Neurosurgery, The University of Michigan, Ann Arbor, Michigan., Altshuler D; Department of Neurosurgery, The University of Michigan, Ann Arbor, Michigan., Hollon T; Department of Neurosurgery, The University of Michigan, Ann Arbor, Michigan., Edwards DM; Department of Radiation Oncology, The University of Michigan, Ann Arbor, Michigan., Wahl DR; Department of Radiation Oncology, The University of Michigan, Ann Arbor, Michigan; Department of Neurosurgery, The University of Michigan, Ann Arbor, Michigan., Lawrence TS; Department of Radiation Oncology, The University of Michigan, Ann Arbor, Michigan., Cao Y; Department of Radiation Oncology, The University of Michigan, Ann Arbor, Michigan; Department of Radiology, The University of Michigan, Ann Arbor, Michigan; Department of Biomedical Engineering, The University of Michigan, Ann Arbor, Michigan.
Source: International journal of radiation oncology, biology, physics [Int J Radiat Oncol Biol Phys] 2025 Jul 01; Vol. 122 (3), pp. 605-610. Date of Electronic Publication: 2025 Mar 08.
Publication Type: Journal Article; Clinical Trial, Phase II
Journal Info: Publisher: Elsevier, Inc Country of Publication: United States NLM ID: 7603616 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-355X (Electronic) Linking ISSN: 03603016 NLM ISO Abbreviation: Int J Radiat Oncol Biol Phys Subsets: MEDLINE
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  Data: A Phase 2 Study of Multiparametric Magnetic Resonance Imaging-Guided High-Dose Response-Adaptive Radiation Therapy With Concurrent Temozolomide in Patients With Newly Diagnosed Glioblastoma: Results From an Interim Analysis.
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  Data: <searchLink fieldCode="AU" term="%22Kim+MM%22">Kim MM</searchLink>; Department of Radiation Oncology, The University of Michigan, Ann Arbor, Michigan. Electronic address: michekim@med.umich.edu.<br /><searchLink fieldCode="AU" term="%22Aryal+MP%22">Aryal MP</searchLink>; Department of Radiation Oncology, The University of Michigan, Ann Arbor, Michigan.<br /><searchLink fieldCode="AU" term="%22Suresh+K%22">Suresh K</searchLink>; Department of Radiation Oncology, The University of Michigan, Ann Arbor, Michigan; Department of Biostatistics, The University of Michigan, Ann Arbor, Michigan.<br /><searchLink fieldCode="AU" term="%22Rosen+BS%22">Rosen BS</searchLink>; Department of Radiation Oncology, The University of Michigan, Ann Arbor, Michigan.<br /><searchLink fieldCode="AU" term="%22Parmar+H%22">Parmar H</searchLink>; Department of Radiology, The University of Michigan, Ann Arbor, Michigan.<br /><searchLink fieldCode="AU" term="%22You+D%22">You D</searchLink>; Department of Radiation Oncology, The University of Michigan, Ann Arbor, Michigan.<br /><searchLink fieldCode="AU" term="%22Leung+D%22">Leung D</searchLink>; Department of Neurology, The University of Michigan, Ann Arbor, Michigan.<br /><searchLink fieldCode="AU" term="%22Clarke+N%22">Clarke N</searchLink>; Department of Neurology, The University of Michigan, Ann Arbor, Michigan.<br /><searchLink fieldCode="AU" term="%22Fortunato+J%22">Fortunato J</searchLink>; Department of Neurology, The University of Michigan, Ann Arbor, Michigan.<br /><searchLink fieldCode="AU" term="%22Al-Holou+W%22">Al-Holou W</searchLink>; Department of Neurosurgery, The University of Michigan, Ann Arbor, Michigan.<br /><searchLink fieldCode="AU" term="%22Heth+J%22">Heth J</searchLink>; Department of Neurosurgery, The University of Michigan, Ann Arbor, Michigan.<br /><searchLink fieldCode="AU" term="%22Altshuler+D%22">Altshuler D</searchLink>; Department of Neurosurgery, The University of Michigan, Ann Arbor, Michigan.<br /><searchLink fieldCode="AU" term="%22Hollon+T%22">Hollon T</searchLink>; Department of Neurosurgery, The University of Michigan, Ann Arbor, Michigan.<br /><searchLink fieldCode="AU" term="%22Edwards+DM%22">Edwards DM</searchLink>; Department of Radiation Oncology, The University of Michigan, Ann Arbor, Michigan.<br /><searchLink fieldCode="AU" term="%22Wahl+DR%22">Wahl DR</searchLink>; Department of Radiation Oncology, The University of Michigan, Ann Arbor, Michigan; Department of Neurosurgery, The University of Michigan, Ann Arbor, Michigan.<br /><searchLink fieldCode="AU" term="%22Lawrence+TS%22">Lawrence TS</searchLink>; Department of Radiation Oncology, The University of Michigan, Ann Arbor, Michigan.<br /><searchLink fieldCode="AU" term="%22Cao+Y%22">Cao Y</searchLink>; Department of Radiation Oncology, The University of Michigan, Ann Arbor, Michigan; Department of Radiology, The University of Michigan, Ann Arbor, Michigan; Department of Biomedical Engineering, The University of Michigan, Ann Arbor, Michigan.
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  Data: <searchLink fieldCode="JN" term="%227603616%22">International journal of radiation oncology, biology, physics</searchLink> [Int J Radiat Oncol Biol Phys] 2025 Jul 01; Vol. 122 (3), pp. 605-610. <i>Date of Electronic Publication: </i>2025 Mar 08.
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  Data: Journal Article; Clinical Trial, Phase II
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%2C+Inc%22">Elsevier, Inc </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7603616 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1879-355X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203603016%22">03603016 </searchLink><i>NLM ISO Abbreviation: </i>Int J Radiat Oncol Biol Phys <i>Subsets: </i>MEDLINE
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