Genetic evidence of methotrexate's protective role against Parkinson's disease: A Mendelian randomization and co-localization study.

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Title: Genetic evidence of methotrexate's protective role against Parkinson's disease: A Mendelian randomization and co-localization study.
Authors: Zou FS; State Key Laboratory of Traditional Chinese Medicine Syndrome, The First Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou 510405, China; Department of Rheumatology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, China; Guangdong Clinical Research Academy of Chinese Medicine, Guangzhou, China., Liu MY; State Key Laboratory of Traditional Chinese Medicine Syndrome, The First Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou 510405, China; Department of Rheumatology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, China; Guangdong Clinical Research Academy of Chinese Medicine, Guangzhou, China. Electronic address: 343991629@qq.com., Ma XN; State Key Laboratory of Traditional Chinese Medicine Syndrome, The First Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou 510405, China; Department of Rheumatology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, China; Guangdong Clinical Research Academy of Chinese Medicine, Guangzhou, China., Shi MF; State Key Laboratory of Traditional Chinese Medicine Syndrome, The First Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou 510405, China; Department of Rheumatology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, China; Guangdong Clinical Research Academy of Chinese Medicine, Guangzhou, China., Feng W; The second Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou 510006, China; Joint Immunology Program, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510006, China., Xu Q; State Key Laboratory of Traditional Chinese Medicine Syndrome, The First Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou 510405, China; Department of Rheumatology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, China; Guangdong Clinical Research Academy of Chinese Medicine, Guangzhou, China. Electronic address: fjksg@163.com.
Source: International immunopharmacology [Int Immunopharmacol] 2025 Apr 16; Vol. 152, pp. 114386. Date of Electronic Publication: 2025 Mar 09.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1705 (Electronic) Linking ISSN: 15675769 NLM ISO Abbreviation: Int Immunopharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Genetic evidence of methotrexate's protective role against Parkinson's disease: A Mendelian randomization and co-localization study.
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  Data: <searchLink fieldCode="AU" term="%22Zou+FS%22">Zou FS</searchLink>; State Key Laboratory of Traditional Chinese Medicine Syndrome, The First Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou 510405, China; Department of Rheumatology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, China; Guangdong Clinical Research Academy of Chinese Medicine, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Liu+MY%22">Liu MY</searchLink>; State Key Laboratory of Traditional Chinese Medicine Syndrome, The First Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou 510405, China; Department of Rheumatology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, China; Guangdong Clinical Research Academy of Chinese Medicine, Guangzhou, China. Electronic address: 343991629@qq.com.<br /><searchLink fieldCode="AU" term="%22Ma+XN%22">Ma XN</searchLink>; State Key Laboratory of Traditional Chinese Medicine Syndrome, The First Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou 510405, China; Department of Rheumatology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, China; Guangdong Clinical Research Academy of Chinese Medicine, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Shi+MF%22">Shi MF</searchLink>; State Key Laboratory of Traditional Chinese Medicine Syndrome, The First Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou 510405, China; Department of Rheumatology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, China; Guangdong Clinical Research Academy of Chinese Medicine, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Feng+W%22">Feng W</searchLink>; The second Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou 510006, China; Joint Immunology Program, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510006, China.<br /><searchLink fieldCode="AU" term="%22Xu+Q%22">Xu Q</searchLink>; State Key Laboratory of Traditional Chinese Medicine Syndrome, The First Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou 510405, China; Department of Rheumatology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, China; Guangdong Clinical Research Academy of Chinese Medicine, Guangzhou, China. Electronic address: fjksg@163.com.
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  Data: <searchLink fieldCode="JN" term="%22100965259%22">International immunopharmacology</searchLink> [Int Immunopharmacol] 2025 Apr 16; Vol. 152, pp. 114386. <i>Date of Electronic Publication: </i>2025 Mar 09.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science%22">Elsevier Science </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>100965259 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1878-1705 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215675769%22">15675769 </searchLink><i>NLM ISO Abbreviation: </i>Int Immunopharmacol <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.intimp.2025.114386
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        Text: English
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      – TitleFull: Genetic evidence of methotrexate's protective role against Parkinson's disease: A Mendelian randomization and co-localization study.
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              Text: 2025 Apr 16
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