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Enhanced mitochondrial function and delivery from adipose-derived stem cell spheres via the EZH2-H3K27me3-PPARγ pathway for advanced therapy.

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Title: Enhanced mitochondrial function and delivery from adipose-derived stem cell spheres via the EZH2-H3K27me3-PPARγ pathway for advanced therapy.
Authors: Chang MM; Department of Cell Biology and Anatomy, College of Medicine, National Cheng Kung University, No. 1, University Road, Tainan, 70101, Taiwan.; Medical Device Innovation Center, National Cheng Kung University, Tainan, 70101, Taiwan., Chu DT; Faculty of Applied Sciences, International School, Vietnam National University, Hanoi, 1000, Vietnam., Lin SC; Division of Plastic and Reconstructive Surgery, Tainan Municipal An-Nan Hospital-China Medical University, Tainan, 70965, Taiwan., Lee JS; Department of Cell Biology and Anatomy, College of Medicine, National Cheng Kung University, No. 1, University Road, Tainan, 70101, Taiwan.; Division of Neurosurgery, Department of Surgery, National Cheng Kung University Hospital, Tainan, 701401, Taiwan.; Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, 70101, Taiwan., Vu TD; Faculty of Applied Sciences, International School, Vietnam National University, Hanoi, 1000, Vietnam., Vu HT; Faculty of Applied Sciences, International School, Vietnam National University, Hanoi, 1000, Vietnam., Ramasamy TS; Stem Cell Biology Laboratory, Department of Molecular Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, 50603, Malaysia., Lin SP; Institute of Biotechnology, College of Bio-Resources and Agriculture, National Taiwan University, Taipei, 10672, Taiwan., Wu CC; Department of Cell Biology and Anatomy, College of Medicine, National Cheng Kung University, No. 1, University Road, Tainan, 70101, Taiwan. joshccwu@mail.ncku.edu.tw.; Medical Device Innovation Center, National Cheng Kung University, Tainan, 70101, Taiwan. joshccwu@mail.ncku.edu.tw.; Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, 70101, Taiwan. joshccwu@mail.ncku.edu.tw.; Department of Biomedical Engineering, National Cheng Kung University, Tainan, 70101, Taiwan. joshccwu@mail.ncku.edu.tw.; International Center for Wound Repair and Regeneration, National Cheng Kung University, Tainan, 70101, Taiwan. joshccwu@mail.ncku.edu.tw.
Source: Stem cell research & therapy [Stem Cell Res Ther] 2025 Mar 11; Vol. 16 (1), pp. 129. Date of Electronic Publication: 2025 Mar 11.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101527581 Publication Model: Electronic Cited Medium: Internet ISSN: 1757-6512 (Electronic) Linking ISSN: 17576512 NLM ISO Abbreviation: Stem Cell Res Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Enhanced mitochondrial function and delivery from adipose-derived stem cell spheres via the EZH2-H3K27me3-PPARγ pathway for advanced therapy.
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  Data: <searchLink fieldCode="AU" term="%22Chang+MM%22">Chang MM</searchLink>; Department of Cell Biology and Anatomy, College of Medicine, National Cheng Kung University, No. 1, University Road, Tainan, 70101, Taiwan.; Medical Device Innovation Center, National Cheng Kung University, Tainan, 70101, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chu+DT%22">Chu DT</searchLink>; Faculty of Applied Sciences, International School, Vietnam National University, Hanoi, 1000, Vietnam.<br /><searchLink fieldCode="AU" term="%22Lin+SC%22">Lin SC</searchLink>; Division of Plastic and Reconstructive Surgery, Tainan Municipal An-Nan Hospital-China Medical University, Tainan, 70965, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lee+JS%22">Lee JS</searchLink>; Department of Cell Biology and Anatomy, College of Medicine, National Cheng Kung University, No. 1, University Road, Tainan, 70101, Taiwan.; Division of Neurosurgery, Department of Surgery, National Cheng Kung University Hospital, Tainan, 701401, Taiwan.; Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, 70101, Taiwan.<br /><searchLink fieldCode="AU" term="%22Vu+TD%22">Vu TD</searchLink>; Faculty of Applied Sciences, International School, Vietnam National University, Hanoi, 1000, Vietnam.<br /><searchLink fieldCode="AU" term="%22Vu+HT%22">Vu HT</searchLink>; Faculty of Applied Sciences, International School, Vietnam National University, Hanoi, 1000, Vietnam.<br /><searchLink fieldCode="AU" term="%22Ramasamy+TS%22">Ramasamy TS</searchLink>; Stem Cell Biology Laboratory, Department of Molecular Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, 50603, Malaysia.<br /><searchLink fieldCode="AU" term="%22Lin+SP%22">Lin SP</searchLink>; Institute of Biotechnology, College of Bio-Resources and Agriculture, National Taiwan University, Taipei, 10672, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wu+CC%22">Wu CC</searchLink>; Department of Cell Biology and Anatomy, College of Medicine, National Cheng Kung University, No. 1, University Road, Tainan, 70101, Taiwan. joshccwu@mail.ncku.edu.tw.; Medical Device Innovation Center, National Cheng Kung University, Tainan, 70101, Taiwan. joshccwu@mail.ncku.edu.tw.; Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, 70101, Taiwan. joshccwu@mail.ncku.edu.tw.; Department of Biomedical Engineering, National Cheng Kung University, Tainan, 70101, Taiwan. joshccwu@mail.ncku.edu.tw.; International Center for Wound Repair and Regeneration, National Cheng Kung University, Tainan, 70101, Taiwan. joshccwu@mail.ncku.edu.tw.
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  Data: <searchLink fieldCode="JN" term="%22101527581%22">Stem cell research & therapy</searchLink> [Stem Cell Res Ther] 2025 Mar 11; Vol. 16 (1), pp. 129. <i>Date of Electronic Publication: </i>2025 Mar 11.
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              Text: 2025 Mar 11
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