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Interleukin-11 expressed in the polyp-enriched fibroblast subset is a potential therapeutic target in Peutz-Jeghers syndrome.

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Title: Interleukin-11 expressed in the polyp-enriched fibroblast subset is a potential therapeutic target in Peutz-Jeghers syndrome.
Authors: Domènech-Moreno E; HiLIFE-Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland.; iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, Helsinki, Finland., Lim WW; National Heart Research Institute Singapore, National Heart Centre Singapore, Singapore, Singapore.; Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, Singapore, Singapore., Montrose MG; HiLIFE-Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland.; iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, Helsinki, Finland., Sévigny M; Translational Cancer Medicine Program, University of Helsinki, Helsinki, Finland.; Faculty of Biological and Environmental Sciences, Molecular and Integrative Biosciences Research Program, University of Helsinki, Helsinki, Finland., Brandt A; HiLIFE-Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland.; iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, Helsinki, Finland., Lemmetyinen TT; Translational Cancer Medicine Program, University of Helsinki, Helsinki, Finland.; Faculty of Biological and Environmental Sciences, Molecular and Integrative Biosciences Research Program, University of Helsinki, Helsinki, Finland., Viitala EW; Translational Cancer Medicine Program, University of Helsinki, Helsinki, Finland.; Faculty of Biological and Environmental Sciences, Molecular and Integrative Biosciences Research Program, University of Helsinki, Helsinki, Finland., Mäkelä TP; HiLIFE-Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland.; iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, Helsinki, Finland., Cook SA; National Heart Research Institute Singapore, National Heart Centre Singapore, Singapore, Singapore.; Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, Singapore, Singapore.; MRC-London Institute of Medical Sciences, Hammersmith Hospital Campus, London, UK., Ollila S; Translational Cancer Medicine Program, University of Helsinki, Helsinki, Finland.; Faculty of Biological and Environmental Sciences, Molecular and Integrative Biosciences Research Program, University of Helsinki, Helsinki, Finland.
Source: The Journal of pathology [J Pathol] 2025 May; Vol. 266 (1), pp. 66-80. Date of Electronic Publication: 2025 Mar 11.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: John Wiley And Sons Country of Publication: England NLM ID: 0204634 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-9896 (Electronic) Linking ISSN: 00223417 NLM ISO Abbreviation: J Pathol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Interleukin-11 expressed in the polyp-enriched fibroblast subset is a potential therapeutic target in Peutz-Jeghers syndrome.
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  Data: <searchLink fieldCode="AU" term="%22Domènech-Moreno+E%22">Domènech-Moreno E</searchLink>; HiLIFE-Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland.; iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Lim+WW%22">Lim WW</searchLink>; National Heart Research Institute Singapore, National Heart Centre Singapore, Singapore, Singapore.; Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Montrose+MG%22">Montrose MG</searchLink>; HiLIFE-Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland.; iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Sévigny+M%22">Sévigny M</searchLink>; Translational Cancer Medicine Program, University of Helsinki, Helsinki, Finland.; Faculty of Biological and Environmental Sciences, Molecular and Integrative Biosciences Research Program, University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Brandt+A%22">Brandt A</searchLink>; HiLIFE-Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland.; iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Lemmetyinen+TT%22">Lemmetyinen TT</searchLink>; Translational Cancer Medicine Program, University of Helsinki, Helsinki, Finland.; Faculty of Biological and Environmental Sciences, Molecular and Integrative Biosciences Research Program, University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Viitala+EW%22">Viitala EW</searchLink>; Translational Cancer Medicine Program, University of Helsinki, Helsinki, Finland.; Faculty of Biological and Environmental Sciences, Molecular and Integrative Biosciences Research Program, University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Mäkelä+TP%22">Mäkelä TP</searchLink>; HiLIFE-Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland.; iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Cook+SA%22">Cook SA</searchLink>; National Heart Research Institute Singapore, National Heart Centre Singapore, Singapore, Singapore.; Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, Singapore, Singapore.; MRC-London Institute of Medical Sciences, Hammersmith Hospital Campus, London, UK.<br /><searchLink fieldCode="AU" term="%22Ollila+S%22">Ollila S</searchLink>; Translational Cancer Medicine Program, University of Helsinki, Helsinki, Finland.; Faculty of Biological and Environmental Sciences, Molecular and Integrative Biosciences Research Program, University of Helsinki, Helsinki, Finland.
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  Data: <searchLink fieldCode="JN" term="%220204634%22">The Journal of pathology</searchLink> [J Pathol] 2025 May; Vol. 266 (1), pp. 66-80. <i>Date of Electronic Publication: </i>2025 Mar 11.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22John+Wiley+And+Sons%22">John Wiley And Sons </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>0204634 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1096-9896 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200223417%22">00223417 </searchLink><i>NLM ISO Abbreviation: </i>J Pathol <i>Subsets: </i>MEDLINE
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              Text: 2025 May
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