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Adjuvant PD-1 Blockade With Camrelizumab for Nasopharyngeal Carcinoma: The DIPPER Randomized Clinical Trial.

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Title: Adjuvant PD-1 Blockade With Camrelizumab for Nasopharyngeal Carcinoma: The DIPPER Randomized Clinical Trial.
Authors: Liang YL; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China., Liu X; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.; Chinese Society of Clinical Oncology, Beijing, China., Shen LF; Department of Oncology, Xiangya Hospital, Central South University, Changsha, China., Hu GY; Tongji Hospital, Huazhong University of Science and Technology, Wuhan, China., Zou GR; Department of Oncology, Panyu Central Hospital, Guangzhou, China., Zhang N; Department of Radiation Oncology, First People's Hospital of Foshan, Foshan, China., Chen CB; Department of Radiation Oncology, Fujian Medical University Cancer Hospital, Fuzhou, China., Chen XZ; Department of Radiation Oncology, Zhejiang Cancer Hospital, Hangzhou, China., Zhu XD; Department of Radiation Oncology, Affiliated Tumor Hospital of Guangxi Medical University, Nanning, China., Yuan YW; Department of Radiation Oncology, Affiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou, China., Yang KY; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China., Jin F; Department of Oncology, The Affiliated Hospital of Guizhou Medical University, Guiyang, China.; Department of Oncology, The Affiliated Cancer Hospital of Guizhou Medical University, Guiyang, China., Hu WH; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China., Xie FY; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.; Chinese Society of Clinical Oncology, Beijing, China., Huang Y; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China., Han F; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China., Tang LL; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.; Chinese Society of Clinical Oncology, Beijing, China., Mao YP; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.; Chinese Society of Clinical Oncology, Beijing, China., Lu LX; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China., Sun R; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China., He YX; Department of Oncology, Xiangya Hospital, Central South University, Changsha, China., Zhou YY; Department of Oncology, Xiangya Hospital, Central South University, Changsha, China., Long GX; Tongji Hospital, Huazhong University of Science and Technology, Wuhan, China., Tang J; Department of Oncology, Panyu Central Hospital, Guangzhou, China., Chen LS; Department of Radiation Oncology, First People's Hospital of Foshan, Foshan, China., Zong JF; Department of Radiation Oncology, Fujian Medical University Cancer Hospital, Fuzhou, China., Jin T; Department of Radiation Oncology, Zhejiang Cancer Hospital, Hangzhou, China., Li L; Department of Radiation Oncology, Affiliated Tumor Hospital of Guangxi Medical University, Nanning, China., Lin J; Department of Radiation Oncology, Affiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou, China., Huang J; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China., Gong XY; Department of Oncology, The Affiliated Hospital of Guizhou Medical University, Guiyang, China.; Department of Oncology, The Affiliated Cancer Hospital of Guizhou Medical University, Guiyang, China., Zhou GQ; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China., Chen L; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China., Li WF; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China., Chen YP; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.; Chinese Society of Clinical Oncology, Beijing, China., Xu C; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China., Lin L; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China., Huang SH; Department of Radiation Oncology, Princess Margaret Cancer Center, Toronto, Ontario, Canada.; University of Toronto, Toronto, Ontario, Canada., Huang SW; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China., Wang YQ; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China., Huang CL; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China., Feng HX; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China., Hou M; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China., Chen CH; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China., Zheng SF; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China., Li YQ; Emergency Department, Sun Yat-sen University Cancer Center, Guangzhou, China., Hong SB; Department of Endocrinology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China., Jie YS; Department of Infectious Diseases, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China., Li H; Department of Rheumatology and Immunology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China., Yun JP; Department of Pathology, Sun Yat-sen University Cancer Center, Guangzhou, China., Zang SB; Department of Pathology, Sun Yat-sen University Cancer Center, Guangzhou, China., Liu SR; Department of Pathology, Sun Yat-sen University Cancer Center, Guangzhou, China., Lin QG; Department of Ultrasound, Sun Yat-sen University Cancer Center, Guangzhou, China., Li HJ; Department of Radiology, Sun Yat-sen University Cancer Center, Guangzhou, China., Tian L; Department of Radiology, Sun Yat-sen University Cancer Center, Guangzhou, China., Liu LZ; Department of Radiology, Sun Yat-sen University Cancer Center, Guangzhou, China., Zhao HY; Department of Medical Oncology, Sun Yat-sen University Cancer Center, Guangzhou, China., Li JB; Clinical Trials Center, Sun Yat-sen University Cancer Center, Guangzhou, China., Lin AH; Department of Medical Statistics, School of Public Health, Sun Yat-sen University, Guangzhou, China., Liu N; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.; Chinese Society of Clinical Oncology, Beijing, China., Zhang Y; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China., Guo R; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China., Ma J; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.; Chinese Society of Clinical Oncology, Beijing, China., Sun Y; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.; Chinese Society of Clinical Oncology, Beijing, China.
Source: JAMA [JAMA] 2025 May 13; Vol. 333 (18), pp. 1589-1598.
Publication Type: Clinical Trial, Phase III; Journal Article; Multicenter Study; Randomized Controlled Trial
Journal Info: Publisher: American Medical Association Country of Publication: United States NLM ID: 7501160 Publication Model: Print Cited Medium: Internet ISSN: 1538-3598 (Electronic) Linking ISSN: 00987484 NLM ISO Abbreviation: JAMA Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Adjuvant PD-1 Blockade With Camrelizumab for Nasopharyngeal Carcinoma: The DIPPER Randomized Clinical Trial.
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  Data: <searchLink fieldCode="AU" term="%22Liang+YL%22">Liang YL</searchLink>; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Liu+X%22">Liu X</searchLink>; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.; Chinese Society of Clinical Oncology, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Shen+LF%22">Shen LF</searchLink>; Department of Oncology, Xiangya Hospital, Central South University, Changsha, China.<br /><searchLink fieldCode="AU" term="%22Hu+GY%22">Hu GY</searchLink>; Tongji Hospital, Huazhong University of Science and Technology, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Zou+GR%22">Zou GR</searchLink>; Department of Oncology, Panyu Central Hospital, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhang+N%22">Zhang N</searchLink>; Department of Radiation Oncology, First People's Hospital of Foshan, Foshan, China.<br /><searchLink fieldCode="AU" term="%22Chen+CB%22">Chen CB</searchLink>; Department of Radiation Oncology, Fujian Medical University Cancer Hospital, Fuzhou, China.<br /><searchLink fieldCode="AU" term="%22Chen+XZ%22">Chen XZ</searchLink>; Department of Radiation Oncology, Zhejiang Cancer Hospital, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhu+XD%22">Zhu XD</searchLink>; Department of Radiation Oncology, Affiliated Tumor Hospital of Guangxi Medical University, Nanning, China.<br /><searchLink fieldCode="AU" term="%22Yuan+YW%22">Yuan YW</searchLink>; Department of Radiation Oncology, Affiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Yang+KY%22">Yang KY</searchLink>; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Jin+F%22">Jin F</searchLink>; Department of Oncology, The Affiliated Hospital of Guizhou Medical University, Guiyang, China.; Department of Oncology, The Affiliated Cancer Hospital of Guizhou Medical University, Guiyang, China.<br /><searchLink fieldCode="AU" term="%22Hu+WH%22">Hu WH</searchLink>; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Xie+FY%22">Xie FY</searchLink>; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.; Chinese Society of Clinical Oncology, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Huang+Y%22">Huang Y</searchLink>; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Han+F%22">Han F</searchLink>; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Tang+LL%22">Tang LL</searchLink>; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.; Chinese Society of Clinical Oncology, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Mao+YP%22">Mao YP</searchLink>; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.; Chinese Society of Clinical Oncology, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Lu+LX%22">Lu LX</searchLink>; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Sun+R%22">Sun R</searchLink>; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22He+YX%22">He YX</searchLink>; Department of Oncology, Xiangya Hospital, Central South University, Changsha, China.<br /><searchLink fieldCode="AU" term="%22Zhou+YY%22">Zhou YY</searchLink>; Department of Oncology, Xiangya Hospital, Central South University, Changsha, China.<br /><searchLink fieldCode="AU" term="%22Long+GX%22">Long GX</searchLink>; Tongji Hospital, Huazhong University of Science and Technology, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Tang+J%22">Tang J</searchLink>; Department of Oncology, Panyu Central Hospital, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Chen+LS%22">Chen LS</searchLink>; Department of Radiation Oncology, First People's Hospital of Foshan, Foshan, China.<br /><searchLink fieldCode="AU" term="%22Zong+JF%22">Zong JF</searchLink>; Department of Radiation Oncology, Fujian Medical University Cancer Hospital, Fuzhou, China.<br /><searchLink fieldCode="AU" term="%22Jin+T%22">Jin T</searchLink>; Department of Radiation Oncology, Zhejiang Cancer Hospital, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Li+L%22">Li L</searchLink>; Department of Radiation Oncology, Affiliated Tumor Hospital of Guangxi Medical University, Nanning, China.<br /><searchLink fieldCode="AU" term="%22Lin+J%22">Lin J</searchLink>; Department of Radiation Oncology, Affiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Huang+J%22">Huang J</searchLink>; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Gong+XY%22">Gong XY</searchLink>; Department of Oncology, The Affiliated Hospital of Guizhou Medical University, Guiyang, China.; Department of Oncology, The Affiliated Cancer Hospital of Guizhou Medical University, Guiyang, China.<br /><searchLink fieldCode="AU" term="%22Zhou+GQ%22">Zhou GQ</searchLink>; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Chen+L%22">Chen L</searchLink>; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Li+WF%22">Li WF</searchLink>; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Chen+YP%22">Chen YP</searchLink>; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.; Chinese Society of Clinical Oncology, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Xu+C%22">Xu C</searchLink>; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Lin+L%22">Lin L</searchLink>; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Huang+SH%22">Huang SH</searchLink>; Department of Radiation Oncology, Princess Margaret Cancer Center, Toronto, Ontario, Canada.; University of Toronto, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Huang+SW%22">Huang SW</searchLink>; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Wang+YQ%22">Wang YQ</searchLink>; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Huang+CL%22">Huang CL</searchLink>; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Feng+HX%22">Feng HX</searchLink>; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Hou+M%22">Hou M</searchLink>; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Chen+CH%22">Chen CH</searchLink>; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Zheng+SF%22">Zheng SF</searchLink>; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Li+YQ%22">Li YQ</searchLink>; Emergency Department, Sun Yat-sen University Cancer Center, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Hong+SB%22">Hong SB</searchLink>; Department of Endocrinology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Jie+YS%22">Jie YS</searchLink>; Department of Infectious Diseases, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Li+H%22">Li H</searchLink>; Department of Rheumatology and Immunology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Yun+JP%22">Yun JP</searchLink>; Department of Pathology, Sun Yat-sen University Cancer Center, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Zang+SB%22">Zang SB</searchLink>; Department of Pathology, Sun Yat-sen University Cancer Center, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Liu+SR%22">Liu SR</searchLink>; Department of Pathology, Sun Yat-sen University Cancer Center, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Lin+QG%22">Lin QG</searchLink>; Department of Ultrasound, Sun Yat-sen University Cancer Center, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Li+HJ%22">Li HJ</searchLink>; Department of Radiology, Sun Yat-sen University Cancer Center, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Tian+L%22">Tian L</searchLink>; Department of Radiology, Sun Yat-sen University Cancer Center, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Liu+LZ%22">Liu LZ</searchLink>; Department of Radiology, Sun Yat-sen University Cancer Center, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhao+HY%22">Zhao HY</searchLink>; Department of Medical Oncology, Sun Yat-sen University Cancer Center, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Li+JB%22">Li JB</searchLink>; Clinical Trials Center, Sun Yat-sen University Cancer Center, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Lin+AH%22">Lin AH</searchLink>; Department of Medical Statistics, School of Public Health, Sun Yat-sen University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Liu+N%22">Liu N</searchLink>; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.; Chinese Society of Clinical Oncology, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Guo+R%22">Guo R</searchLink>; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Ma+J%22">Ma J</searchLink>; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.; Chinese Society of Clinical Oncology, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Sun+Y%22">Sun Y</searchLink>; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.; Chinese Society of Clinical Oncology, Beijing, China.
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  Data: <searchLink fieldCode="JN" term="%227501160%22">JAMA</searchLink> [JAMA] 2025 May 13; Vol. 333 (18), pp. 1589-1598.
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      – TitleFull: Adjuvant PD-1 Blockade With Camrelizumab for Nasopharyngeal Carcinoma: The DIPPER Randomized Clinical Trial.
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            NameFull: Zhu XD
      – PersonEntity:
          Name:
            NameFull: Yuan YW
      – PersonEntity:
          Name:
            NameFull: Yang KY
      – PersonEntity:
          Name:
            NameFull: Jin F
      – PersonEntity:
          Name:
            NameFull: Hu WH
      – PersonEntity:
          Name:
            NameFull: Xie FY
      – PersonEntity:
          Name:
            NameFull: Huang Y
      – PersonEntity:
          Name:
            NameFull: Han F
      – PersonEntity:
          Name:
            NameFull: Tang LL
      – PersonEntity:
          Name:
            NameFull: Mao YP
      – PersonEntity:
          Name:
            NameFull: Lu LX
      – PersonEntity:
          Name:
            NameFull: Sun R
      – PersonEntity:
          Name:
            NameFull: He YX
      – PersonEntity:
          Name:
            NameFull: Zhou YY
      – PersonEntity:
          Name:
            NameFull: Long GX
      – PersonEntity:
          Name:
            NameFull: Tang J
      – PersonEntity:
          Name:
            NameFull: Chen LS
      – PersonEntity:
          Name:
            NameFull: Zong JF
      – PersonEntity:
          Name:
            NameFull: Jin T
      – PersonEntity:
          Name:
            NameFull: Li L
      – PersonEntity:
          Name:
            NameFull: Lin J
      – PersonEntity:
          Name:
            NameFull: Huang J
      – PersonEntity:
          Name:
            NameFull: Gong XY
      – PersonEntity:
          Name:
            NameFull: Zhou GQ
      – PersonEntity:
          Name:
            NameFull: Chen L
      – PersonEntity:
          Name:
            NameFull: Li WF
      – PersonEntity:
          Name:
            NameFull: Chen YP
      – PersonEntity:
          Name:
            NameFull: Xu C
      – PersonEntity:
          Name:
            NameFull: Lin L
      – PersonEntity:
          Name:
            NameFull: Huang SH
      – PersonEntity:
          Name:
            NameFull: Huang SW
      – PersonEntity:
          Name:
            NameFull: Wang YQ
      – PersonEntity:
          Name:
            NameFull: Huang CL
      – PersonEntity:
          Name:
            NameFull: Feng HX
      – PersonEntity:
          Name:
            NameFull: Hou M
      – PersonEntity:
          Name:
            NameFull: Chen CH
      – PersonEntity:
          Name:
            NameFull: Zheng SF
      – PersonEntity:
          Name:
            NameFull: Li YQ
      – PersonEntity:
          Name:
            NameFull: Hong SB
      – PersonEntity:
          Name:
            NameFull: Jie YS
      – PersonEntity:
          Name:
            NameFull: Li H
      – PersonEntity:
          Name:
            NameFull: Yun JP
      – PersonEntity:
          Name:
            NameFull: Zang SB
      – PersonEntity:
          Name:
            NameFull: Liu SR
      – PersonEntity:
          Name:
            NameFull: Lin QG
      – PersonEntity:
          Name:
            NameFull: Li HJ
      – PersonEntity:
          Name:
            NameFull: Tian L
      – PersonEntity:
          Name:
            NameFull: Liu LZ
      – PersonEntity:
          Name:
            NameFull: Zhao HY
      – PersonEntity:
          Name:
            NameFull: Li JB
      – PersonEntity:
          Name:
            NameFull: Lin AH
      – PersonEntity:
          Name:
            NameFull: Liu N
      – PersonEntity:
          Name:
            NameFull: Zhang Y
      – PersonEntity:
          Name:
            NameFull: Guo R
      – PersonEntity:
          Name:
            NameFull: Ma J
      – PersonEntity:
          Name:
            NameFull: Sun Y
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 13
              M: 05
              Text: 2025 May 13
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 1538-3598
          Numbering:
            – Type: volume
              Value: 333
            – Type: issue
              Value: 18
          Titles:
            – TitleFull: JAMA
              Type: main
ResultId 1